Streptomyces roseirectus

General Information

Streptomyces roseirectus is a fascinating microorganism belonging to the genus Streptomyces, which is renowned for its prolific production of secondary metabolites. One of the most notable characteristics of S. roseirectus is its ability to produce a variety of bioactive compounds, including antibiotics, antifungals, and antitumor agents. This makes it a valuable organism in pharmaceutical research and biotechnology. Streptomyces species are known for their complex life cycle, which includes the formation of a mycelium and spore chains, contributing to their adaptability and survival in diverse environments. S. roseirectus is particularly interesting due to its unique pigmentation, which can range from pink to red, providing a visual marker that can be useful in laboratory settings for identification and study. The genome of S. roseirectus is also of significant interest. Like other Streptomyces species, it has a large, linear chromosome with a high G+C content, which is associated with the organism's ability to produce a wide array of secondary metabolites. This genetic complexity offers numerous opportunities for genetic and metabolic engineering, aiming to enhance the production of existing compounds or to discover new ones. In summary, Streptomyces roseirectus is a microorganism of great interest due to its prolific production of bioactive compounds, unique pigmentation, and complex genetic makeup, making it a valuable subject for research in natural product discovery and biotechnology.

Streptomyces roseirectus is a fascinating actinobacterium known for its remarkable ability to produce a variety of bioactive compounds, making it a valuable organism in pharmaceutical research. This species is particularly interesting due to its unique metabolic pathways that allow it to synthesize secondary metabolites, which have potential applications in drug development, especially in the fight against antibiotic-resistant bacteria. One of the standout features of S. roseirectus is its production of antibiotics and antifungal agents, which are derived from its complex biosynthetic capabilities. These compounds are not only crucial for the organism's survival in competitive environments but also hold promise for therapeutic use in human medicine. Additionally, S. roseirectus has been studied for its role in soil health and plant growth promotion. Its interactions with plant roots can enhance nutrient availability and stimulate plant defenses, making it a candidate for use in sustainable agriculture practices. The organism's ability to thrive in diverse environments, coupled with its genetic tractability, makes S. roseirectus an excellent model for studying the genetics of secondary metabolite production. Researchers are particularly interested in its genome, which contains numerous gene clusters responsible for the biosynthesis of various natural products. This genomic information can provide insights into the evolutionary adaptations of actinobacteria and their ecological roles. In summary, Streptomyces roseirectus stands out not only for its biotechnological potential but also for its contributions to our understanding of microbial ecology and natural product chemistry. Its unique characteristics and capabilities make it a subject of ongoing research in both microbiology and pharmacology.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Kitasatosporales

Family: Streptomycetaceae

Genus: Streptomyces

Species: Streptomyces roseirectus

NCBI ID

2768066

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/014/489/635/GCA_014489635.1_ASM1448963v1

File for sequence-based predictions:
GCA_014489635.1_ASM1448963v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Streptomyces roseirectus is a member of the genus Streptomyces, which is known for its significant role in the production of antibiotics and other bioactive compounds. While S. roseirectus itself is not commonly associated with human disease, its relatives have been implicated in various clinical contexts. Antibiotic production is one of the most notable aspects of this genus, with many species contributing to the development of clinically important antibiotics such as streptomycin and tetracycline. This highlights the potential of S. roseirectus in therapeutic applications and its relevance in the pharmaceutical industry. In terms of pathogenicity, members of the Streptomyces genus are generally considered non-pathogenic to humans; however, they can occasionally be involved in opportunistic infections, particularly in immunocompromised individuals. The ability of some Streptomyces species to produce a variety of secondary metabolites may also play a role in immune evasion, although specific mechanisms related to S. roseirectus are not well-documented. Furthermore, the potential for antimicrobial resistance is a critical area of concern, as the overuse of antibiotics derived from Streptomyces can lead to the emergence of resistant strains. Understanding the resistance mechanisms in this genus is essential for developing effective treatment strategies. Overall, while Streptomyces roseirectus may not have direct clinical implications as a pathogen, its contributions to antibiotic production and the broader implications of its relatives in human health and disease make it a significant organism in microbiological and pharmaceutical research.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Streptomyces roseirectus is a species of actinobacteria commonly found in soil ecosystems and decaying organic matter. This microorganism thrives in environments rich in organic material, where it plays a crucial role in the decomposition process. Its ability to break down complex organic compounds contributes to nutrient cycling within the ecosystem, making it an essential player in maintaining soil health and fertility. In particular, Streptomyces roseirectus is often associated with terrestrial biomes, where it can be found in both temperate and tropical regions. The organism exhibits a remarkable capacity for environmental adaptation, allowing it to survive in varying conditions, including changes in moisture and nutrient availability. Notably, Streptomyces roseirectus engages in symbiotic relationships with plants, promoting plant growth through the production of bioactive compounds. These interactions can enhance plant resistance to pathogens and improve overall plant health, showcasing the organism's importance in agricultural ecosystems. Furthermore, this species is known for its production of various secondary metabolites, which can have antimicrobial properties. This characteristic not only aids in its survival by inhibiting competing microorganisms but also highlights its potential applications in biotechnology and pharmaceuticals. Overall, Streptomyces roseirectus exemplifies the intricate relationships within soil biomes, contributing to ecological balance and offering benefits that extend to agricultural practices and human health.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Streptomyces roseirectus is known for its significant contributions to various industrial applications, particularly in the fields of biotechnology, pharmaceutical development, and waste management. This actinobacterium is recognized for its ability to produce a wide range of bioactive compounds, including antibiotics, which are crucial in the development of new pharmaceuticals. For instance, it has been documented to produce compounds that exhibit antimicrobial properties, making it a valuable resource in the search for new drugs to combat resistant bacterial strains. In the realm of biotechnology, Streptomyces roseirectus is involved in fermentation processes that can lead to the production of secondary metabolites. These metabolites are not only important for their medicinal properties but also have applications in agriculture as biopesticides and biofertilizers, promoting sustainable farming practices. Moreover, this microorganism plays a role in waste management through its ability to degrade complex organic materials. Its enzymatic activity allows it to break down pollutants in contaminated environments, making it a candidate for bioremediation efforts aimed at cleaning up hazardous waste sites. Additionally, Streptomyces roseirectus has potential in biofuel production. Its metabolic pathways can be harnessed to convert biomass into biofuels, contributing to renewable energy solutions. The organism's ability to ferment various substrates can be utilized in the production of bioethanol, providing an alternative to fossil fuels. Overall, Streptomyces roseirectus exemplifies the versatility of microorganisms in industrial applications, showcasing its importance in pharmaceutical development, biotechnology, waste management, and biofuel production.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	google/gemini-flash-1.5	meta-llama/llama-3-70b-instruct:nitro	google/gemma-7b-it	google/gemini-pro	meta-llama/llama-3-8b-instruct:nitro	anthropic/claude-3-haiku:beta	openchat/openchat-7b	microsoft/phi-3-mini-128k-instruct	mistralai/mixtral-8x7b-instruct:nitro	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	anthropic/claude-3.5-sonnet	anthropic/claude-3.5-sonnet	google/gemini-pro-1.5	google/gemini-pro-1.5	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	perplexity/llama-3-sonar-small-32k-chat	perplexity/llama-3-sonar-small-32k-chat	mistralai/mistral-7b-instruct	mistralai/mistral-7b-instruct
Motility	FALSE	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain negative ✗	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain variable ✗
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	N/A	aerobic ✓	N/A	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	true ✗	true ✗	false ✓	true ✗	true ✗	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗
Biofilm formation	N/A	true	true	true	true	true	true	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	false	true	true	true	true	true	false	false	true	false	false	true	true	false	false	true	true	true	true	false	false	true	true	true	true	false	false
Host association	FALSE	true ✗	true ✗	false ✓	false ✓	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗
Plant pathogenicity	N/A	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false
Spore formation	TRUE	true ✓	true ✓	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Hemolysis	N/A	gamma	N/A	alpha	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	tail	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗

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