Gulosibacter hominis

General Information

Source: gpt-4o-2024-05-13

Gulosibacter hominis is a fascinating microorganism that has garnered attention due to its unique habitat and potential applications. This bacterium was first isolated from human clinical specimens, which makes it particularly interesting for medical microbiology. One of the key characteristics of Gulosibacter hominis is its ability to thrive in the human body, suggesting it may play a role in human health or disease. From a research perspective, Gulosibacter hominis is valuable because it belongs to the family Microbacteriaceae, a group known for their diverse metabolic capabilities. This opens up possibilities for studying its metabolic pathways and potential biotechnological applications. For instance, members of this family are often involved in the degradation of complex organic compounds, which could be harnessed for environmental or industrial processes. Another noteworthy aspect of Gulosibacter hominis is its genetic makeup. The genome of this bacterium can provide insights into its adaptability and survival mechanisms within the human host. Understanding these genetic traits can lead to the development of new therapeutic strategies or diagnostic tools. In summary, Gulosibacter hominis stands out due to its human-associated habitat, diverse metabolic potential, and intriguing genetic characteristics. These features make it a valuable subject for ongoing and future research in both medical and environmental microbiology.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Micrococcales

Family: Microbacteriaceae

Genus: Gulosibacter

Species: Gulosibacter hominis

NCBI ID

2770504

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/904/848/455/GCA_904848455.1_401468-18.fasta

File for sequence-based predictions:
GCA_904848455.1_401468-18.fasta_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The microorganism Gulosibacter hominis is a member of the human gut microbiota, and its clinical implications are still being explored. It has been associated with the maintenance of gut health and may play a role in the fermentation of dietary fibers, contributing to the production of short-chain fatty acids (SCFAs) that are beneficial for intestinal health. However, the specific pathogenicity of Gulosibacter hominis is not well-documented, and it is not currently recognized as a significant pathogen in human disease. Emerging research suggests that alterations in the gut microbiome, including the presence or absence of Gulosibacter hominis, may be linked to various metabolic disorders and inflammatory conditions. Its role in immune modulation is also under investigation, as gut bacteria can influence the host's immune response and potentially affect susceptibility to infections. In terms of antimicrobial resistance, there is limited information available regarding Gulosibacter hominis. However, the study of gut microbiota often reveals complex interactions with antibiotic treatments, which can lead to shifts in microbial populations and the emergence of resistant strains. Currently, there are no established medical applications such as probiotics, vaccines, or therapeutics specifically involving Gulosibacter hominis. Further research is needed to fully understand its role in human health and disease, as well as its potential therapeutic applications.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Gulosibacter hominis is a bacterium that is primarily associated with the human gastrointestinal tract. This microorganism thrives in the anaerobic environments of the gut, where it plays a significant role in the digestion of complex carbohydrates and the fermentation of dietary fibers. Its presence is crucial for maintaining a balanced gut microbiome, contributing to the overall health of the host by aiding in nutrient absorption and producing short-chain fatty acids, which are beneficial for intestinal health. In terms of ecological niches, Gulosibacter hominis is often found in association with other gut microbiota, engaging in symbiotic relationships that enhance the metabolic capabilities of the gut ecosystem. This bacterium can adapt to varying conditions within the gut, such as changes in pH and the availability of nutrients, showcasing its resilience and ecological versatility. Furthermore, Gulosibacter hominis may also interact with the host's immune system, potentially influencing immune responses and contributing to the prevention of pathogenic infections. Its role in the gut microbiome underscores the importance of microbial diversity in maintaining host health and homeostasis.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Gulosibacter hominis has shown potential in various industrial applications, particularly in the fields of biotechnology, waste management, and pharmaceutical development. This organism is known for its ability to participate in fermentation processes, which can be harnessed for the production of valuable metabolites and bioactive compounds. For instance, Gulosibacter hominis can be utilized in the fermentation of organic substrates to produce organic acids, which are important in the food and chemical industries. In the realm of waste management, Gulosibacter hominis has demonstrated capabilities in biodegradation, particularly in the breakdown of complex organic materials. This property can be leveraged for the treatment of wastewater and the remediation of contaminated environments, making it a valuable asset in environmental biotechnology. Moreover, the enzymatic activity of Gulosibacter hominis is noteworthy, as it can produce specific enzymes that are useful in various industrial processes, including the textile and paper industries, where enzymes are employed to enhance the efficiency of production processes. In pharmaceutical development, the metabolites produced during the fermentation process by Gulosibacter hominis may have therapeutic properties, leading to the discovery of new drugs or health supplements. Overall, the diverse applications of Gulosibacter hominis highlight its significance in advancing sustainable industrial practices and developing innovative biotechnological solutions.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 8

LLM predicted phenotypes: 5

Phenotype	High-quality annotation	google/palm-2-chat-bison-32k	google/gemini-flash-1.5	anthropic/claude-3-haiku:beta	mistralai/mixtral-8x7b-instruct:nitro	google/gemini-pro	meta-llama/llama-3-70b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	openchat/openchat-7b	google/gemma-7b-it	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	anthropic/claude-3.5-sonnet	anthropic/claude-3.5-sonnet	google/gemini-pro-1.5	google/gemini-pro-1.5	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	mistralai/mistral-7b-instruct	mistralai/mistral-7b-instruct	meta-llama/llama-3-8b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct
Motility	FALSE	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	true ✗	false ✓	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Gram staining	gram stain positive	gram stain negative ✗	gram stain negative ✗	gram stain negative ✗	gram stain negative ✗	gram stain negative ✗	gram stain positive ✓	gram stain negative ✗	gram stain positive ✓	gram stain negative ✗	N/A	gram stain negative ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain variable ✗	N/A	gram stain negative ✗	N/A	gram stain negative ✗
Aerophilicity	aerobic	anaerobic ✗	N/A	N/A	facultatively anaerobic ✗	anaerobic ✗	N/A	N/A	N/A	N/A	facultatively anaerobic ✗	facultatively anaerobic ✗	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	anaerobic ✗	anaerobic ✗	aerobic ✓	aerobic ✓	aerotolerant ✗	aerotolerant ✗	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Biofilm formation	N/A	false	true	true	true	false	true	true	false	true	true	true	false	false	false	false	false	false	false	false	true	true	false	false	true	true	false	false
Animal pathogenicity	N/A	false	true	true	false	false	true	false	false	false	false	false	false	false	false	false	true	true	false	false	true	true	false	false	false	false	false	false
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	true	true	true	true	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false
Host association	N/A	false	true	true	true	true	true	true	true	false	false	false	true	true	true	true	true	true	false	false	true	true	true	true	true	true	false	false
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	N/A	N/A	gamma	alpha	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗

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