Mycobacterium senriense

General Information

Mycobacterium senriense is a species of bacteria within the genus Mycobacterium, which is known for its complex cell wall structure and slow growth rate. This organism is particularly interesting due to its unique genetic makeup and its potential implications in both environmental and clinical settings. One of the most notable characteristics of M. senriense is its ability to survive in diverse environments, which makes it a subject of interest for studies on microbial ecology and environmental microbiology. Its resilience and adaptability are thought to be linked to its robust cell wall, which provides protection against various environmental stresses. From a clinical perspective, Mycobacterium senriense has been isolated in cases of human infections, although it is not as well-known or as widely studied as other pathogenic mycobacteria like Mycobacterium tuberculosis or Mycobacterium leprae. This makes it a valuable organism for research into emerging mycobacterial infections and the development of new diagnostic and therapeutic approaches. Additionally, the study of M. senriense can provide insights into the evolutionary biology of mycobacteria, given its distinct phylogenetic position within the genus. Understanding its genetic and phenotypic traits can help elucidate the evolutionary pathways that have led to the diversity observed in mycobacterial species. Overall, Mycobacterium senriense is a fascinating organism that holds significant potential for advancing our knowledge in various fields of microbiology, from environmental studies to clinical research and evolutionary biology.

Mycobacterium senriense is a species of the genus Mycobacterium that has garnered interest due to its unique ecological niche and potential implications in environmental microbiology. This organism is primarily isolated from soil and has been identified in various environmental samples, indicating its role in nutrient cycling and soil health. One of the most intriguing aspects of M. senriense is its ability to degrade complex organic compounds, which positions it as a potential candidate for bioremediation efforts, particularly in contaminated environments. The metabolic pathways utilized by M. senriense are of significant interest, as they may provide insights into the mechanisms of biodegradation and the organism's adaptation to diverse ecological conditions. Research into this species could lead to advancements in our understanding of microbial ecology and the development of sustainable practices for environmental cleanup. Furthermore, the genetic and biochemical characteristics of M. senriense may reveal novel enzymes or metabolic processes that could be harnessed in biotechnology applications. Overall, Mycobacterium senriense represents a fascinating subject for research, with its potential contributions to both environmental science and biotechnology making it a valuable organism for further study.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Mycobacteriales

Family: Mycobacteriaceae

Genus: Mycobacterium

Species: Mycobacterium senriense

NCBI ID

2775496

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/019/668/465/GCA_019668465.1_ASM1966846v1

File for sequence-based predictions:
GCA_019668465.1_ASM1966846v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Mycobacterium senriense is a member of the Mycobacterium genus, which is known for its clinical significance primarily in relation to tuberculosis and other mycobacterial infections. Although M. senriense is less commonly discussed than its more notorious relatives, it has been associated with pulmonary infections and can be a cause of nontuberculous mycobacterial (NTM) diseases in immunocompromised individuals. Clinical implications of M. senriense include its potential role in chronic lung disease, particularly in patients with underlying conditions such as chronic obstructive pulmonary disease (COPD) or cystic fibrosis. In terms of pathogenicity, M. senriense exhibits characteristics typical of mycobacteria, including a robust cell wall that contributes to its virulence and ability to evade the immune response. This organism can survive within macrophages, a key component of the human immune system, by inhibiting phagosome-lysosome fusion, thus allowing it to persist and replicate within host cells. Regarding antimicrobial resistance, there is limited data on the specific resistance patterns of M. senriense, but like other mycobacteria, it may exhibit resistance to common antitubercular drugs. This poses challenges in treatment, particularly in cases where the organism is misidentified or not adequately tested for drug susceptibility. While M. senriense is not typically used in medical applications such as probiotics or vaccines, understanding its role in human health and disease is crucial for developing effective treatment strategies. Continued research is necessary to fully elucidate its clinical relevance and to improve diagnostic and therapeutic approaches for infections caused by this organism.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Mycobacterium senriense is a species of bacteria that is primarily associated with soil environments and aerosolized particles. This microorganism thrives in terrestrial biomes, particularly in regions with a high organic matter content, such as decaying plant material and humus-rich soils. Its presence is often linked to areas with significant microbial diversity, where it plays a crucial role in nutrient cycling and organic matter decomposition. In these soil habitats, Mycobacterium senriense contributes to the breakdown of complex organic compounds, facilitating the release of nutrients that are essential for plant growth. This process underscores its importance in maintaining soil health and fertility. Additionally, it has been observed in aerosolized environments, where it can be found in dust particles, potentially influencing air quality and human health. The organism exhibits notable symbiotic relationships with other soil microorganisms, enhancing its survival and adaptability in various ecological niches. Its ability to withstand harsh environmental conditions, such as drought and nutrient-poor soils, further exemplifies its ecological resilience. Overall, Mycobacterium senriense plays a significant role in the soil microbiome, contributing to ecosystem stability and functioning.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Mycobacterium senriense has shown potential in various industrial applications, particularly in the fields of biotechnology and waste management. This organism is known for its ability to degrade complex organic compounds, making it a candidate for biodegradation processes in contaminated environments. Its enzymatic activity can facilitate the breakdown of pollutants, thus contributing to effective waste treatment solutions. In the realm of biofuel production, Mycobacterium senriense may play a role in the conversion of biomass into biofuels through fermentation processes. By utilizing its metabolic pathways, this microorganism can potentially enhance the efficiency of biofuel generation from organic waste materials. Furthermore, there is interest in the pharmaceutical development sector, where Mycobacterium senriense could be explored for its unique metabolic products. These metabolites may have therapeutic properties, leading to the discovery of new drugs or treatments. Overall, the versatility of Mycobacterium senriense in biodegradation, fermentation, and potential pharmaceutical applications highlights its significance in sustainable industrial practices.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	google/gemini-pro-1.5	anthropic/claude-3.5-sonnet	google/gemini-flash-1.5	meta-llama/llama-3-70b-instruct:nitro	google/gemma-7b-it	google/gemini-pro	anthropic/claude-3-haiku:beta	openchat/openchat-7b	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mistral-7b-instruct	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	meta-llama/llama-3-8b-instruct:nitro	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	perplexity/llama-3-sonar-small-32k-chat	perplexity/llama-3-sonar-small-32k-chat	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct
Motility	FALSE	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain negative ✗	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain variable ✗	N/A	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	aerobic ✓	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A
Extreme environment tolerance	N/A	false	false	true	false	true	false	true	false	false	true	false	false	true	true	true	false	false	false	false	false	false	true	true	true	true
Biofilm formation	N/A	true	true	true	true	true	true	true	false	true	true	true	true	true	true	true	true	true	false	false	true	true	true	true	true	true
Animal pathogenicity	TRUE	true ✓	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	true ✓	false ✗	false ✗	true ✓	true ✓	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗
Biosafety level	biosafety level 2	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 3 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 3 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓
Health association	N/A	true	true	true	true	true	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true	true
Host association	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Hemolysis	N/A	N/A	N/A	N/A	N/A	alpha	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗

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