Streptomyces durocortorensis

General Information

Streptomyces durocortorensis is a fascinating microorganism belonging to the genus Streptomyces, which is renowned for its prolific production of secondary metabolites. One of the most intriguing aspects of S. durocortorensis is its ability to produce a wide array of bioactive compounds, including antibiotics, antifungals, and antitumor agents. This makes it a valuable subject of study in pharmaceutical research and biotechnology. Streptomyces species are known for their complex life cycle and filamentous growth, which is reminiscent of fungal mycelia. This characteristic allows them to thrive in diverse environments, particularly in soil where they play a crucial role in decomposing organic matter. The production of geosmin, a compound responsible for the earthy smell of soil, is another notable feature of Streptomyces species, including S. durocortorensis. From a genetic perspective, S. durocortorensis possesses a large genome with a high G+C content, typical of the genus. This genetic richness provides a vast reservoir of biosynthetic gene clusters that can be harnessed for the discovery of new natural products. The potential for novel drug discovery is particularly high with S. durocortorensis, given its unique metabolic capabilities and the ongoing interest in mining Streptomyces genomes for new therapeutic agents. In summary, Streptomyces durocortorensis stands out due to its remarkable ability to produce diverse and potent bioactive compounds, its complex and adaptive life cycle, and its significant genetic potential for biotechnological applications. These attributes make it a microorganism of great interest to researchers in various fields, particularly those focused on natural product discovery and environmental microbiology.

Streptomyces durocortorensis is a fascinating species of actinobacteria known for its remarkable ability to produce a variety of bioactive compounds, including antibiotics and antifungal agents. This organism is part of the Streptomyces genus, which is renowned for its prolific secondary metabolite production, making it a valuable resource in pharmaceutical research and development. One of the most interesting aspects of S. durocortorensis is its ecological role in soil environments, where it contributes to the decomposition of organic matter and the cycling of nutrients. This capability not only aids in soil health but also highlights the organism's potential in bioremediation efforts, where it could be utilized to degrade pollutants or enhance soil fertility. Unique to S. durocortorensis is its genetic makeup, which has been studied for insights into the biosynthesis of its secondary metabolites. Researchers are particularly interested in the pathways that lead to the production of novel compounds, which could have significant implications for drug discovery. The genetic diversity within this species may also provide opportunities for the development of new strains with enhanced properties or capabilities. Furthermore, S. durocortorensis has been shown to exhibit a range of antimicrobial activities, making it a candidate for further exploration in the fight against antibiotic-resistant pathogens. Its ability to produce compounds that inhibit the growth of various bacteria and fungi underscores its potential as a source of new therapeutic agents. In summary, Streptomyces durocortorensis stands out not only for its ecological importance but also for its contributions to biotechnology and medicine. Its rich repertoire of bioactive compounds and the genetic insights it offers make it a subject of ongoing research, with the potential to yield significant benefits in various fields.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Kitasatosporales

Family: Streptomycetaceae

Genus: Streptomyces

Species: Streptomyces durocortorensis

NCBI ID

2811104

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/031/760/065/GCA_031760065.1_ASM3176006v1

File for sequence-based predictions:
GCA_031760065.1_ASM3176006v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Streptomyces durocortorensis is a member of the genus Streptomyces, which is known for its significant role in the production of antibiotics and other bioactive compounds. While specific clinical implications of Streptomyces durocortorensis are not extensively documented, its relatives have been associated with various important clinical aspects. Antibiotic production is a key feature of this genus, with many species contributing to the development of clinically relevant antibiotics such as streptomycin and tetracycline. This highlights the potential of Streptomyces durocortorensis in therapeutics and the ongoing search for new antimicrobial agents in the face of rising antimicrobial resistance. In terms of pathogenicity, members of the Streptomyces genus are generally considered non-pathogenic to humans; however, they can occasionally be implicated in opportunistic infections, particularly in immunocompromised individuals. The ability of some Streptomyces species to produce a variety of secondary metabolites may also play a role in immune evasion strategies, although specific mechanisms for Streptomyces durocortorensis have not been well characterized. Furthermore, the ecological role of Streptomyces durocortorensis in soil and its interactions with plants suggest potential applications in agriculture and biocontrol, which could indirectly influence human health by promoting sustainable practices. Overall, while direct clinical implications of Streptomyces durocortorensis remain to be fully elucidated, its association with antibiotic production and potential roles in human health and disease underscore its relevance in microbiological and medical research.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Streptomyces durocortorensis is a species of actinobacteria that is primarily found in soil ecosystems and decaying organic matter. This microorganism thrives in environments rich in organic material, where it plays a crucial role in the decomposition process. Its ability to break down complex organic compounds contributes significantly to nutrient cycling within these biomes. Soil Biomes: In soil, Streptomyces durocortorensis is often associated with the rhizosphere, the region of soil directly influenced by root secretions and associated soil microorganisms. Here, it engages in nutrient exchange and can promote plant health through the production of bioactive compounds that inhibit pathogenic fungi and bacteria. This interaction exemplifies a form of symbiosis, where the bacterium benefits from the organic compounds released by plants, while simultaneously providing protective benefits to the plants. Decaying Organic Matter: In environments characterized by decaying plant material, Streptomyces durocortorensis contributes to the breakdown of cellulose and lignin, essential processes in the carbon cycle. By decomposing these materials, it helps release nutrients back into the soil, making them available for other organisms. This role is vital for maintaining the health and productivity of terrestrial ecosystems. Overall, Streptomyces durocortorensis is an important player in terrestrial biomes, particularly in nutrient-rich soils and organic matter-rich environments, where it supports both ecological balance and plant health through its various interactions and adaptations.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Streptomyces durocortorensis has shown significant potential in various industrial applications, particularly in the fields of biotechnology, pharmaceutical development, and waste management. This actinobacterium is known for its ability to produce a wide range of bioactive compounds, including antibiotics, which are crucial in the development of new pharmaceuticals. Its role in fermentation processes allows for the production of these valuable metabolites, making it a key player in the pharmaceutical industry. In the realm of biotechnology, Streptomyces durocortorensis is utilized for its enzymatic activities, particularly in the production of enzymes that can be applied in various industrial processes. These enzymes can be harnessed for applications such as biodegradation, where they help break down complex organic materials, thus contributing to waste management efforts. This capability is particularly important in the treatment of agricultural and industrial waste, where the breakdown of pollutants is essential for environmental sustainability. Moreover, the potential of Streptomyces durocortorensis in biofuel production is noteworthy. By participating in fermentation processes, it can aid in the conversion of biomass into biofuels, providing a renewable energy source that can help reduce reliance on fossil fuels. The organism's ability to degrade lignocellulosic materials makes it a candidate for enhancing the efficiency of biofuel production processes. Overall, Streptomyces durocortorensis exemplifies the versatility of microorganisms in industrial applications, particularly through its contributions to fermentation, enzyme production, and biodegradation, making it a valuable asset in the ongoing pursuit of sustainable industrial practices.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	google/gemini-flash-1.5	anthropic/claude-3.5-sonnet	meta-llama/llama-3-8b-instruct:nitro	anthropic/claude-3-haiku:beta	perplexity/llama-3-sonar-small-32k-chat	google/gemma-7b-it	openchat/openchat-7b	mistralai/mixtral-8x7b-instruct:nitro	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	openai/gpt-4	openai/gpt-4	meta-llama/llama-3-70b-instruct:nitro	meta-llama/llama-3-70b-instruct:nitro	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	google/gemini-pro	google/gemini-pro	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	mistralai/mistral-7b-instruct	mistralai/mistral-7b-instruct
Motility	FALSE	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain negative ✗	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain variable ✗	N/A	gram stain positive ✓
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A
Extreme environment tolerance	N/A	true	true	true	true	false	true	false	true	false	false	true	true	true	true	false	false	false	false	true	true	false	false	false	false	true	true	true	true
Biofilm formation	N/A	true	true	true	true	true	true	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false
Animal pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 3 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 3 ✗	biosafety level 3 ✗	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	false	true	true	true	true	true	false	true	false	false	false	false	true	true	true	true	true	true	true	true	true	true	true	true	false	false	false	false
Host association	FALSE	true ✗	true ✗	true ✗	false ✓	true ✗	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Hemolysis	N/A	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	tail	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗

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