Nocardiopsis eucommiae

General Information

Nocardiopsis eucommiae is a fascinating microorganism belonging to the genus Nocardiopsis, which is known for its diverse metabolic capabilities and ecological versatility. This species was first isolated from the bark of the Chinese medicinal plant Eucommia ulmoides, which is notable because it suggests a potential symbiotic relationship or specialized adaptation to this unique niche. One of the most intriguing aspects of Nocardiopsis eucommiae is its ability to produce a variety of bioactive compounds. These compounds have shown potential in pharmaceutical applications, particularly as antibiotics and antifungal agents. The production of these secondary metabolites makes Nocardiopsis eucommiae a valuable subject for biotechnological research, especially in the search for new drugs to combat resistant pathogens. Additionally, Nocardiopsis eucommiae exhibits a remarkable ability to degrade complex organic materials. This characteristic is particularly valuable in environmental biotechnology, where it can be utilized for the bioremediation of contaminated sites. The organism's enzymatic machinery allows it to break down pollutants, making it a potential candidate for cleaning up environmental toxins. From a genetic perspective, Nocardiopsis eucommiae is interesting due to its relatively large genome, which encodes a wide array of enzymes and metabolic pathways. This genetic diversity underpins its adaptability and metabolic flexibility, allowing it to thrive in various environments and utilize different substrates for growth. In summary, Nocardiopsis eucommiae is a microorganism of significant interest due to its bioactive compound production, environmental bioremediation potential, and genetic diversity. These characteristics make it a valuable organism for both pharmaceutical and environmental research, highlighting its potential contributions to science and industry.

Nocardiopsis eucommiae is a fascinating actinobacterium that has garnered attention due to its unique ecological niche and potential biotechnological applications. This microorganism is primarily isolated from soil and is known for its ability to degrade complex organic compounds, making it an important player in soil health and nutrient cycling. Its capacity to produce a variety of secondary metabolites is particularly noteworthy, as these compounds can have significant pharmaceutical implications, including antimicrobial and antifungal properties. One of the most interesting aspects of Nocardiopsis eucommiae is its association with the plant Eucommia ulmoides, which is known for its medicinal properties in traditional Chinese medicine. This symbiotic relationship suggests that N. eucommiae may contribute to the plant's health and resilience, potentially leading to the discovery of novel bioactive compounds that could be harnessed for therapeutic use. Furthermore, the organism's ability to thrive in extreme environments, such as those with high salinity or aridity, makes it a valuable subject for research in extremophiles. Understanding the mechanisms behind its resilience could provide insights into bioremediation strategies and the development of stress-resistant crops. Overall, Nocardiopsis eucommiae stands out not only for its ecological significance but also for its potential contributions to medicine and agriculture.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Streptosporangiales

Family: Nocardiopsaceae

Genus: Nocardiopsis

Species: Nocardiopsis eucommiae

NCBI ID

2831970

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/018/388/625/GCA_018388625.1_ASM1838862v1

File for sequence-based predictions:
GCA_018388625.1_ASM1838862v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The microorganism Nocardiopsis eucommiae is a member of the actinobacteria group and has garnered attention for its potential clinical implications. It is primarily known for its role in the degradation of complex organic materials, which can be beneficial in bioremediation processes. However, its relevance in human health is not as well-established as other members of the Nocardiopsis genus. In terms of pathogenicity, Nocardiopsis eucommiae has been associated with rare cases of infections, particularly in immunocompromised individuals. These infections can manifest as cutaneous lesions or pulmonary infections, although such occurrences are infrequent. The organism's ability to produce various bioactive compounds may also contribute to its pathogenic potential, although specific mechanisms of immune evasion remain largely unexplored. Furthermore, there is emerging interest in the antimicrobial properties of Nocardiopsis eucommiae, particularly in its ability to produce secondary metabolites that may exhibit antimicrobial resistance against certain pathogens. This characteristic could have implications for the development of new therapeutic agents. While there are no widely recognized medical applications such as probiotics or vaccines directly linked to Nocardiopsis eucommiae, its role in natural product chemistry and potential for biotechnological applications in drug discovery make it a subject of ongoing research. Overall, while Nocardiopsis eucommiae is not a common pathogen, its unique properties warrant further investigation to fully understand its clinical relevance.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Nocardiopsis eucommiae is a filamentous bacterium commonly found in soil and decaying organic matter, particularly in tropical and subtropical regions. This microorganism thrives in environments rich in organic material, where it plays a crucial role in the decomposition process. Its ability to degrade complex organic compounds makes it an important contributor to nutrient cycling within these ecosystems. Soil Biomes: In soil biomes, Nocardiopsis eucommiae is often associated with the rhizosphere of plants, where it can engage in mutualistic relationships. This bacterium can enhance soil fertility by breaking down organic matter, thus releasing essential nutrients that are beneficial for plant growth. Its presence can improve soil structure and promote the health of the surrounding flora. Decaying Organic Matter: In environments characterized by decaying organic matter, such as leaf litter or compost, Nocardiopsis eucommiae plays a vital role in the breakdown of complex organic substances. This process not only aids in nutrient recycling but also contributes to the formation of humus, which is essential for maintaining soil health. Additionally, Nocardiopsis eucommiae has been noted for its potential in bioremediation, where it can help in the degradation of pollutants, thus showcasing its adaptability to various environmental stresses. Its ability to thrive in diverse habitats underscores its ecological significance and adaptability to changing environmental conditions.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Nocardiopsis eucommiae has shown significant potential in various industrial applications. One of the most notable areas is in biotechnology, where Nocardiopsis eucommiae is utilized for its ability to produce a range of bioactive compounds, including antibiotics and enzymes. This organism is particularly effective in fermentation processes, where it can be harnessed to synthesize valuable metabolites that have pharmaceutical applications. In the realm of waste management, Nocardiopsis eucommiae has demonstrated capabilities in biodegradation, particularly in the breakdown of complex organic materials. This makes it a candidate for use in bioremediation efforts, where it can help in the detoxification of contaminated environments, such as soil and water polluted with industrial waste. Furthermore, the organism is being explored for its role in biofuel production. Its enzymatic activity can facilitate the conversion of biomass into fermentable sugars, which can then be transformed into biofuels through subsequent fermentation processes. This positions Nocardiopsis eucommiae as a valuable player in the development of sustainable energy sources. In summary, Nocardiopsis eucommiae is a versatile microorganism with applications spanning pharmaceutical development, biotechnology, waste management, and biofuel production, showcasing its importance in modern industrial processes.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 8

LLM predicted phenotypes: 5

Phenotype	High-quality annotation	anthropic/claude-3.5-sonnet	google/gemini-pro-1.5	meta-llama/llama-3-8b-instruct:nitro	google/palm-2-chat-bison-32k	google/gemini-flash-1.5	anthropic/claude-3-haiku:beta	perplexity/llama-3-sonar-small-32k-chat	openchat/openchat-7b	mistralai/mixtral-8x7b-instruct:nitro	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	openai/gpt-4	openai/gpt-4	meta-llama/llama-3-70b-instruct:nitro	meta-llama/llama-3-70b-instruct:nitro	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	google/gemini-pro	google/gemini-pro	google/gemma-7b-it	google/gemma-7b-it	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	mistralai/mistral-7b-instruct	mistralai/mistral-7b-instruct
Motility	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain negative ✗	N/A	gram stain variable ✗
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerotolerant ✗	aerobic ✓	N/A	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	TRUE	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	true ✓	false ✗	true ✓	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Biofilm formation	N/A	true	false	true	true	true	true	true	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	true	true	false	true	false	true	true	false	false	false	false	false	false	false	false	false	false	true	true	true	true	true	true	false	false	false	false
Host association	N/A	false	false	false	false	true	true	true	false	false	false	false	false	false	false	false	false	false	true	true	false	false	false	false	true	true	false	false
Plant pathogenicity	FALSE	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	TRUE	true ✓	true ✓	true ✓	false ✗	true ✓	true ✓	true ✓	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗
Hemolysis	N/A	N/A	N/A	N/A	N/A	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	N/A	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	coccus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	coccus	coccus	bacillus	bacillus

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