Streptomyces flavovariabilis

General Information

Streptomyces flavovariabilis is a fascinating microorganism belonging to the genus Streptomyces, which is renowned for its prolific production of secondary metabolites. One of the most notable characteristics of S. flavovariabilis is its ability to produce a wide array of antibiotics and bioactive compounds. This makes it a valuable subject of study in pharmaceutical research and biotechnology. The genus Streptomyces is well-known for its complex life cycle and filamentous growth, which resembles that of fungi. S. flavovariabilis forms a dense, branched mycelium and produces spores that are instrumental in its reproduction and dissemination. Another intriguing aspect of S. flavovariabilis is its potential in bioremediation. This organism has been studied for its ability to degrade various environmental pollutants, making it a candidate for cleaning up contaminated sites. In addition to its antibiotic production and bioremediation capabilities, S. flavovariabilis is also of interest due to its unique metabolic pathways. Researchers are keen on exploring these pathways to understand how this organism synthesizes complex molecules, which could lead to the discovery of new drugs and industrial enzymes. Overall, Streptomyces flavovariabilis stands out due to its diverse metabolic capabilities, antibiotic production, and potential applications in environmental and pharmaceutical fields. Its study not only contributes to our understanding of microbial ecology and evolution but also holds promise for practical applications that can benefit human health and the environment.

Streptomyces flavovariabilis is a fascinating actinobacterium known for its remarkable ability to produce a variety of bioactive compounds, making it a valuable organism in pharmaceutical research. This species is particularly interesting due to its capacity to synthesize antibiotics, which are crucial in the fight against bacterial infections. The unique metabolic pathways of S. flavovariabilis allow it to generate compounds that exhibit antimicrobial, antifungal, and antitumor activities, highlighting its potential in drug discovery and development. One of the standout features of S. flavovariabilis is its ability to thrive in diverse environments, which contributes to its genetic diversity and the production of novel secondary metabolites. This adaptability not only enhances its survival but also increases the likelihood of discovering new compounds with therapeutic potential. Researchers are particularly interested in the genomic and biochemical pathways of this organism, as they may reveal insights into the mechanisms of natural product biosynthesis. Furthermore, S. flavovariabilis has been studied for its role in soil health and plant growth promotion, showcasing its ecological importance. Its interactions with plants and other microorganisms can lead to enhanced nutrient availability and disease resistance, making it a candidate for use in sustainable agriculture practices. In summary, Streptomyces flavovariabilis stands out due to its antibiotic production, genetic diversity, and ecological significance, making it a key player in both medical and environmental research.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Kitasatosporales

Family: Streptomycetaceae

Genus: Streptomyces

Species: Streptomyces flavovariabilis

NCBI ID

284031

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/000/725/785/GCA_000725785.1_Doro.v1.0

File for sequence-based predictions:
GCA_000725785.1_Doro.v1.0_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Streptomyces flavovariabilis is a member of the genus Streptomyces, which is known for its significant role in the production of antibiotics and other bioactive compounds. This species has been studied for its potential in antimicrobial resistance due to its ability to produce various secondary metabolites that can inhibit the growth of pathogenic bacteria. Clinical implications of S. flavovariabilis include its potential use in the development of new therapeutics against resistant strains of bacteria, making it a candidate for further research in the field of antibiotic discovery. In addition to its antimicrobial properties, S. flavovariabilis has been investigated for its role in human health through its potential applications in probiotics. Some studies suggest that certain strains of Streptomyces may contribute to gut health and modulate the immune response, although specific clinical data on S. flavovariabilis is limited. Furthermore, the organism's ability to produce enzymes and metabolites may have implications in bioremediation and environmental health, which indirectly affects human health by reducing the burden of pathogens in the environment. However, it is essential to note that while S. flavovariabilis shows promise, more research is needed to fully understand its clinical relevance and potential applications in medicine.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Streptomyces flavovariabilis is a species of actinobacteria commonly found in soil and decaying organic matter. This microorganism thrives in a variety of terrestrial ecosystems, particularly in nutrient-rich environments where organic decomposition occurs. Its presence is often associated with agricultural soils, where it plays a crucial role in the breakdown of complex organic materials, contributing to nutrient cycling and soil health. In these soil ecosystems, S. flavovariabilis exhibits antibiotic production, which is significant for its ecological niche. This ability allows it to compete effectively with other microorganisms, inhibiting the growth of potential pathogens and thus maintaining a balanced microbial community. The production of antibiotics also highlights its role in biocontrol, making it a valuable organism in sustainable agriculture practices. Additionally, S. flavovariabilis can be found in compost heaps and forest floors, where it contributes to the decomposition process of plant materials. Its interactions with other soil microorganisms can lead to symbiotic relationships, enhancing the overall health of the ecosystem. The adaptability of S. flavovariabilis to varying soil conditions, including pH and moisture levels, further underscores its ecological significance in diverse environments. Overall, Streptomyces flavovariabilis is an essential component of soil biomes, playing a vital role in nutrient cycling, disease suppression, and maintaining ecological balance.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Streptomyces flavovariabilis has shown significant potential in various industrial applications. One of the most notable areas is in biotechnology, where it is utilized for its ability to produce a wide range of bioactive compounds, including antibiotics and enzymes. This organism is particularly known for its role in fermentation, which is a critical process in the production of pharmaceuticals and other bioactive substances. In the realm of waste management, Streptomyces flavovariabilis has demonstrated capabilities in biodegradation, where it can break down complex organic materials, thus aiding in the treatment of waste and reducing environmental pollution. Its enzymatic activity allows it to degrade various pollutants, making it a valuable asset in bioremediation efforts. Furthermore, this microorganism is being explored for its potential in biofuel production. Through fermentation processes, it can convert biomass into biofuels, contributing to sustainable energy solutions. The enzymes produced by Streptomyces flavovariabilis can also enhance the efficiency of biomass conversion, making it a promising candidate in the bioenergy sector. Overall, Streptomyces flavovariabilis is a versatile microorganism with applications spanning pharmaceutical development, waste treatment, and biofuel production, showcasing its importance in modern industrial biotechnology.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 10

LLM predicted phenotypes: 3

Phenotype	High-quality annotation	google/gemini-flash-1.5	anthropic/claude-3.5-sonnet	meta-llama/llama-3-8b-instruct:nitro	google/palm-2-chat-bison-32k	meta-llama/llama-3-70b-instruct:nitro	anthropic/claude-3-haiku:beta	perplexity/llama-3-sonar-small-32k-chat	openchat/openchat-7b	microsoft/phi-3-mini-128k-instruct	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	google/gemma-7b-it	google/gemma-7b-it	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mistral-7b-instruct	mistralai/mistral-7b-instruct	google/gemini-pro	google/gemini-pro
Motility	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain variable ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerotolerant ✗	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	true ✗	true ✗	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓
Biofilm formation	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false	true	true
Animal pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 3 ✗	biosafety level 3 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	false	true	false	true	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true	false	false	true	true
Host association	FALSE	true ✗	true ✗	false ✓	false ✓	true ✗	false ✓	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Hemolysis	N/A	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	tail	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗

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