Streptomyces mutomycini

General Information

Streptomyces mutomycini is a fascinating microorganism belonging to the genus Streptomyces, which is renowned for its prolific production of secondary metabolites. One of the most notable characteristics of S. mutomycini is its ability to produce mutomycins, a group of antibiotics with significant therapeutic potential. These compounds have shown activity against a variety of bacterial pathogens, making S. mutomycini a valuable subject of study in the field of antibiotic research. Another intriguing aspect of S. mutomycini is its complex life cycle, which includes the formation of a mycelial network and the production of spores. This life cycle is not only interesting from a biological standpoint but also has practical implications for the cultivation and harvesting of its antibiotic products. Streptomyces species, including S. mutomycini, are also known for their ability to degrade a wide range of organic materials, contributing to soil health and nutrient cycling. This makes them important players in natural ecosystems and potential candidates for bioremediation efforts. In summary, Streptomyces mutomycini stands out due to its antibiotic production capabilities, complex life cycle, and ecological significance. These characteristics make it a valuable organism for both scientific research and practical applications in medicine and environmental management.

Streptomyces mutomycini is a fascinating actinobacterium known for its remarkable ability to produce a diverse array of bioactive compounds, including antibiotics and other secondary metabolites. This organism is particularly interesting due to its unique ecological niche, often found in soil and decaying organic matter, where it plays a crucial role in nutrient cycling and decomposition processes. One of the standout features of S. mutomycini is its capacity for natural product biosynthesis. It has been shown to produce several novel compounds that exhibit antimicrobial, antifungal, and even anticancer properties, making it a valuable resource for pharmaceutical research. The genetic and metabolic pathways involved in the synthesis of these compounds are of great interest to researchers aiming to discover new drugs and therapeutic agents. Additionally, S. mutomycini is notable for its genetic tractability, which allows scientists to manipulate its genome to enhance the production of desired metabolites or to study the functions of specific genes. This characteristic positions it as a model organism in the field of microbial biotechnology. Furthermore, the organism's ability to thrive in various environmental conditions makes it a subject of study in understanding microbial adaptation and resilience. Its interactions with other microorganisms in the soil ecosystem can provide insights into microbial ecology and the dynamics of microbial communities. In summary, Streptomyces mutomycini stands out not only for its biotechnological potential but also for its ecological significance, making it a valuable organism for ongoing research in microbiology, pharmacology, and environmental science.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Kitasatosporales

Family: Streptomycetaceae

Genus: Streptomyces

Species: Streptomyces mutomycini

NCBI ID

284036

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCF/001/700/505/GCF_001700505.1_ASM170050v1

File for sequence-based predictions:
GCF_001700505.1_ASM170050v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Streptomyces mutomycini is a member of the genus Streptomyces, which is known for its significant role in the production of antibiotics and other bioactive compounds. While S. mutomycini itself is not widely studied in clinical settings, its relatives have been implicated in various infections and have shown potential in antimicrobial resistance research. Clinical implications of this organism may include its potential use in the development of novel therapeutics due to its ability to produce secondary metabolites that can inhibit pathogenic bacteria. In terms of immune evasion, members of the Streptomyces genus have developed mechanisms to survive in hostile environments, which may include the production of biofilms or the secretion of enzymes that degrade host immune factors. This characteristic could be relevant in understanding how certain strains might contribute to chronic infections or biofilm-associated diseases. Furthermore, the exploration of Streptomyces mutomycini in the context of probiotics or vaccine development is an area of interest, as the genus is known for its beneficial interactions with human health. However, more research is needed to fully elucidate the specific clinical relevance of S. mutomycini and its potential applications in medicine.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Streptomyces mutomycini is a species of actinobacteria that is primarily associated with soil ecosystems and decaying organic matter. This microorganism thrives in environments rich in organic material, where it plays a crucial role in the decomposition process. Its presence is often linked to the breakdown of complex organic compounds, contributing to nutrient cycling within the ecosystem. Soil Biomes: In soil biomes, Streptomyces mutomycini is commonly found in the upper layers of the soil, where it interacts with other microorganisms and plant roots. It is known for its ability to produce a variety of bioactive compounds, including antibiotics, which can inhibit the growth of competing bacteria. This not only helps it to establish itself in the soil but also contributes to the overall health of the soil microbiome by controlling pathogenic organisms. Symbiotic Relationships: This microorganism often engages in symbiotic relationships with plants, aiding in nutrient uptake, particularly in nutrient-poor soils. By breaking down organic matter, it releases essential nutrients such as nitrogen and phosphorus, which are vital for plant growth. In return, plants may provide Streptomyces mutomycini with carbohydrates and other organic compounds, creating a mutually beneficial relationship. Adaptation to Environmental Conditions: Streptomyces mutomycini exhibits remarkable adaptability to varying environmental conditions, including changes in moisture and temperature. It can form spores that allow it to survive in harsh conditions, ensuring its persistence in the soil even during unfavorable periods. This resilience is crucial for maintaining its role in the ecosystem, particularly in terrestrial biomes where seasonal changes can significantly impact microbial communities. Overall, Streptomyces mutomycini is an essential component of terrestrial ecosystems, contributing to soil health, nutrient cycling, and plant growth through its various ecological interactions.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Streptomyces mutomycini is known for its significant contributions to various industrial applications, particularly in the fields of biotechnology and pharmaceutical development. This organism is a member of the genus Streptomyces, which is renowned for its ability to produce a wide array of bioactive compounds, including antibiotics and other pharmaceuticals. For instance, Streptomyces mutomycini has been documented to produce unique secondary metabolites that can be harnessed in the development of new drugs, showcasing its potential in pharmaceutical development. In addition to its pharmaceutical applications, Streptomyces mutomycini plays a role in biodegradation processes, where it can break down complex organic materials. This capability is particularly valuable in waste management, as it can be utilized to remediate contaminated environments by degrading pollutants and organic waste through biodegradation processes. Moreover, the enzymatic activities of Streptomyces mutomycini can be exploited in biotechnology for the production of enzymes that are used in various industrial processes. These enzymes can facilitate fermentation processes, which are essential in the production of biofuels and other bioproducts. The ability of this microorganism to thrive in diverse environments further enhances its utility in industrial applications, making it a promising candidate for future research and development in these fields.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	anthropic/claude-3.5-sonnet	google/palm-2-chat-bison-32k	google/gemini-flash-1.5	google/gemini-flash-1.5	meta-llama/llama-3-70b-instruct:nitro	google/gemini-pro	meta-llama/llama-3-8b-instruct:nitro	anthropic/claude-3-haiku:beta	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mistral-7b-instruct	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	perplexity/llama-3-sonar-small-32k-chat	perplexity/llama-3-sonar-small-32k-chat	google/gemma-7b-it	google/gemma-7b-it	openchat/openchat-7b	openchat/openchat-7b	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct
Motility	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	N/A	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	N/A	true	false	true	true	true	false	true	true	true	true	false	false	true	true	true	true	false	false	false	false	true	true	true	true	true	true	true	true
Biofilm formation	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 3 ✗	biosafety level 3 ✗	biosafety level 3 ✗	biosafety level 3 ✗	biosafety level 3 ✗	biosafety level 3 ✗
Health association	N/A	true	true	false	false	true	true	true	true	true	false	false	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false
Host association	FALSE	true ✗	false ✓	true ✗	true ✗	true ✗	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓
Spore formation	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Hemolysis	N/A	N/A	N/A	gamma	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	tail	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	coccus ✗	coccus ✗

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