Streptomyces spinoverrucosus

General Information

Streptomyces spinoverrucosus is a fascinating microorganism belonging to the genus Streptomyces, which is renowned for its prolific production of secondary metabolites. One of the most notable characteristics of S. spinoverrucosus is its ability to produce a wide array of bioactive compounds, including antibiotics, antifungals, and antitumor agents. This makes it a valuable organism in pharmaceutical research and biotechnology. Streptomyces species are known for their complex life cycle, which includes the formation of a mycelium and spore chains, contributing to their unique colony morphology. The production of geosmin, a compound responsible for the earthy smell of soil, is another interesting feature of S. spinoverrucosus, highlighting its ecological role in soil environments. From a genetic perspective, S. spinoverrucosus has a large and complex genome, which encodes numerous biosynthetic gene clusters. These clusters are responsible for the synthesis of its diverse secondary metabolites. The study of these gene clusters can provide insights into novel pathways for drug discovery and development. In summary, Streptomyces spinoverrucosus is a microorganism of significant interest due to its extensive secondary metabolite production, complex life cycle, and ecological importance. Its potential in biotechnological applications and pharmaceutical research continues to make it a subject of extensive scientific study.

Streptomyces spinoverrucosus is a fascinating actinobacterium known for its remarkable ability to produce a diverse array of bioactive compounds, including antibiotics and antifungal agents. This species is part of the larger genus Streptomyces, which is renowned for its role in natural product biosynthesis. What makes S. spinoverrucosus particularly interesting is its unique metabolic pathways that allow it to synthesize compounds with potential pharmaceutical applications. One of the standout features of S. spinoverrucosus is its ability to thrive in extreme environments, which may contribute to its production of novel secondary metabolites. This adaptability not only enhances its survival but also increases the likelihood of discovering new compounds that could be beneficial in medicine. Research into this organism could lead to the identification of new antibiotics, especially in the face of rising antibiotic resistance. Additionally, S. spinoverrucosus has been studied for its ecological role in soil health and nutrient cycling. Its interactions with other microorganisms and plants can provide insights into sustainable agricultural practices. The potential for biotechnological applications, such as bioremediation and the development of natural pesticides, further underscores the value of this organism in research. In summary, Streptomyces spinoverrucosus stands out not only for its biochemical capabilities but also for its ecological significance, making it a valuable subject for ongoing scientific investigation.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Kitasatosporales

Family: Streptomycetaceae

Genus: Streptomyces

Species: Streptomyces spinoverrucosus

NCBI ID

284043

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/014/651/195/GCA_014651195.1_ASM1465119v1

File for sequence-based predictions:
GCA_014651195.1_ASM1465119v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Streptomyces spinoverrucosus is a member of the genus Streptomyces, which is known for its significant role in the production of antibiotics and other bioactive compounds. While Streptomyces spinoverrucosus itself is not commonly associated with human disease, its relatives have been implicated in various clinical contexts. Antibiotic production is one of the most notable aspects of this genus, with many species contributing to the development of clinically important antibiotics such as streptomycin and tetracycline. This highlights the potential of Streptomyces spinoverrucosus in therapeutics and the ongoing search for new antimicrobial agents to combat antimicrobial resistance. In terms of pathogenicity, members of the Streptomyces genus are generally considered non-pathogenic to humans; however, they can occasionally be involved in opportunistic infections, particularly in immunocompromised individuals. The ability of some Streptomyces species to produce a variety of secondary metabolites may also play a role in their interactions with the human microbiome, potentially influencing immune responses. Furthermore, the ecological role of Streptomyces spinoverrucosus in soil and its interactions with plants can have indirect implications for human health, particularly in agriculture and food safety. The use of Streptomyces species in biocontrol and bioremediation underscores their importance in environmental health, which can ultimately affect human health outcomes. Overall, while Streptomyces spinoverrucosus may not have direct clinical implications as a pathogen, its contributions to antibiotic production and its ecological roles are significant in the broader context of human health and disease management.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Streptomyces spinoverrucosus is a species of actinobacteria commonly found in soil and decaying organic matter. This microorganism thrives in a variety of terrestrial biomes, particularly in regions with rich nutrient availability and moisture. Its ecological niche is often associated with the breakdown of complex organic materials, contributing significantly to nutrient cycling within the ecosystem. Soil Biomes: In soil environments, Streptomyces spinoverrucosus plays a crucial role in the decomposition process, breaking down organic compounds and facilitating the release of nutrients back into the soil. This process not only enriches the soil but also supports plant growth, making the organism vital for maintaining soil health and fertility. Symbiotic Relationships: This microorganism is known for its ability to form symbiotic relationships with various plants. It can enhance plant growth by producing phytohormones and other beneficial compounds, which help in nutrient uptake and stress resistance. Such interactions underscore its importance in agricultural ecosystems, where it can be utilized as a natural biofertilizer. Adaptation to Environmental Conditions: Streptomyces spinoverrucosus exhibits remarkable adaptability to varying environmental conditions, including changes in moisture and nutrient levels. Its ability to produce a wide range of secondary metabolites, including antibiotics, allows it to compete effectively with other microorganisms in its habitat, further solidifying its role in the microbial community. In summary, Streptomyces spinoverrucosus is a key player in soil ecosystems, contributing to nutrient cycling, supporting plant health through symbiosis, and demonstrating adaptability to diverse environmental conditions.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Streptomyces spinoverrucosus is known for its significant contributions to various industrial applications. One of the most notable areas is in biotechnology, where it is utilized for the production of antibiotics and other bioactive compounds. This organism is part of the larger genus Streptomyces, which is renowned for its ability to produce a wide range of secondary metabolites through fermentation. For instance, Streptomyces spinoverrucosus has been studied for its potential to synthesize novel antimicrobial agents, which can be crucial in pharmaceutical development. In the realm of waste management, Streptomyces spinoverrucosus has demonstrated capabilities in biodegradation processes. It can break down complex organic materials, making it useful in the treatment of contaminated soils and wastewater. This biodegradation ability is particularly valuable in the remediation of environments polluted with hazardous compounds, showcasing the organism's role in environmental biotechnology. Furthermore, the enzymatic activities of Streptomyces spinoverrucosus are of great interest in biofuel production. The organism can produce enzymes that facilitate the breakdown of lignocellulosic biomass, which is a critical step in the conversion of plant materials into fermentable sugars for bioethanol production. This enzymatic action supports the development of sustainable energy sources, aligning with global efforts to reduce reliance on fossil fuels. Overall, Streptomyces spinoverrucosus exemplifies the potential of microorganisms in various industries, particularly in pharmaceutical development, waste management, and biofuel production, through its unique metabolic capabilities and enzymatic functions.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	google/gemini-flash-1.5	anthropic/claude-3.5-sonnet	meta-llama/llama-3-70b-instruct:nitro	mistralai/mistral-7b-instruct	google/gemini-pro	anthropic/claude-3-haiku:beta	perplexity/llama-3-sonar-small-32k-chat	microsoft/phi-3-mini-128k-instruct	mistralai/mixtral-8x7b-instruct:nitro	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	meta-llama/llama-3-8b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	google/gemma-7b-it	google/gemma-7b-it	openchat/openchat-7b	openchat/openchat-7b
Motility	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain positive ✓
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerotolerant ✗	aerotolerant ✗	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓
Biofilm formation	N/A	true	true	true	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false
Animal pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 3 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 3 ✗	biosafety level 3 ✗	biosafety level 2 ✗	biosafety level 2 ✗
Health association	N/A	false	false	true	false	true	true	true	false	true	false	false	true	true	true	true	false	false	true	true	false	false	true	true	true	true	false	false
Host association	FALSE	true ✗	false ✓	true ✗	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓
Plant pathogenicity	FALSE	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Spore formation	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Hemolysis	N/A	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	N/A	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus

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