Streptomyces gelaticus

General Information

Streptomyces gelaticus is a fascinating microorganism belonging to the genus Streptomyces, which is renowned for its prolific production of secondary metabolites. These metabolites often have significant pharmaceutical applications, including antibiotics, antifungals, and antitumor agents. One of the most noteworthy aspects of S. gelaticus is its ability to produce gelatinase, an enzyme that hydrolyzes gelatin. This characteristic is particularly valuable in industrial and biotechnological applications where gelatin degradation is required. Additionally, Streptomyces species are known for their complex life cycle, which includes the formation of a mycelium and spore chains, contributing to their adaptability and survival in various environments. The genus is also recognized for its soil-dwelling nature, playing a crucial role in the decomposition of organic materials and nutrient cycling in ecosystems. From a research perspective, S. gelaticus is of great interest due to its potential in bioremediation and natural product discovery. The exploration of its genome and metabolic pathways can lead to the identification of novel compounds with therapeutic potential. Furthermore, the study of its enzymatic activities can provide insights into new biocatalysts for industrial processes. In summary, Streptomyces gelaticus stands out for its enzymatic capabilities, ecological significance, and potential in drug discovery and industrial applications, making it a valuable subject of scientific research.*

Streptomyces gelaticus is a fascinating actinobacterium known for its unique ecological niche and biotechnological potential. This species is primarily isolated from cold environments, such as polar regions and high-altitude locations, which contributes to its remarkable ability to thrive in low-temperature conditions. This adaptation not only makes it a subject of interest for studying microbial life in extreme environments but also offers insights into the mechanisms of cold adaptation at a molecular level. One of the most intriguing aspects of S. gelaticus is its capacity to produce a variety of bioactive compounds, including antibiotics and enzymes. The discovery of novel secondary metabolites from this organism could lead to the development of new pharmaceuticals, particularly in the fight against antibiotic-resistant bacteria. Researchers are particularly interested in its potential to yield compounds that can be utilized in agriculture, such as natural pesticides or growth promoters, which could reduce reliance on synthetic chemicals. Furthermore, S. gelaticus has been studied for its role in bioremediation, particularly in the degradation of environmental pollutants. Its ability to break down complex organic compounds makes it a valuable candidate for cleaning up contaminated sites, thus contributing to environmental sustainability. In summary, Streptomyces gelaticus stands out due to its cold-adapted lifestyle, potential for producing novel bioactive compounds, and its applications in bioremediation, making it a significant organism for both ecological and biotechnological research.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Kitasatosporales

Family: Streptomycetaceae

Genus: Streptomyces

Species: Streptomyces gelaticus

NCBI ID

285446

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/014/649/535/GCA_014649535.1_ASM1464953v1

File for sequence-based predictions:
GCA_014649535.1_ASM1464953v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Streptomyces gelaticus is a member of the genus Streptomyces, which is known for its significant role in the production of antibiotics and other bioactive compounds. While S. gelaticus itself is not commonly associated with human disease, its relatives have been implicated in various clinical contexts. Antimicrobial resistance is a notable concern, as some Streptomyces species can harbor genes that confer resistance to multiple classes of antibiotics, complicating treatment options for infections caused by other pathogens. In terms of human health, S. gelaticus may have potential applications in the development of novel therapeutics due to its ability to produce secondary metabolites. These metabolites can exhibit antimicrobial properties, making them candidates for drug development against resistant bacterial strains. Furthermore, the genus Streptomyces is also studied for its role in probiotics, where certain strains may contribute positively to gut health and the overall immune response of the host. However, the specific contributions of S. gelaticus in these areas require further investigation. Overall, while Streptomyces gelaticus may not be directly linked to specific outbreaks or infections, its potential in biotechnology and pharmaceutical applications underscores its relevance in the clinical landscape.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Streptomyces gelaticus is a species of actinobacteria commonly found in soil and marine environments. This microorganism thrives in nutrient-rich substrates, often associated with decaying organic matter, where it plays a crucial role in the decomposition process. Its ability to produce a variety of bioactive compounds makes it significant in the soil ecosystem, contributing to nutrient cycling and the suppression of plant pathogens through its antagonistic properties. In marine biomes, Streptomyces gelaticus has been isolated from sediments and is known to interact with other microorganisms, forming complex communities that enhance the overall health of the marine ecosystem. This species exhibits symbiotic relationships with various marine organisms, potentially aiding in their growth and resilience against environmental stressors. Furthermore, Streptomyces gelaticus is adapted to thrive in extreme environments, such as those with high salinity or varying temperatures, showcasing its ecological versatility. Its metabolic capabilities allow it to utilize a wide range of substrates, making it a key player in the biogeochemical cycles of both terrestrial and aquatic ecosystems. Overall, this microorganism exemplifies the intricate connections within its habitats, highlighting its importance in maintaining ecological balance.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Streptomyces gelaticus has shown significant potential in various industrial applications. One of the most notable areas is in biotechnology, where Streptomyces gelaticus is utilized for its ability to produce a range of bioactive compounds, including antibiotics and enzymes. This organism is particularly valuable in the fermentation process, where it can be harnessed to synthesize secondary metabolites that have pharmaceutical significance. In the realm of waste management, Streptomyces gelaticus has demonstrated capabilities in biodegradation, particularly in the breakdown of complex organic materials. This makes it a candidate for use in bioremediation efforts, where it can help in the detoxification of contaminated environments by degrading pollutants. Furthermore, the enzymatic activity of Streptomyces gelaticus is noteworthy, as it can produce various enzymes that are useful in industrial processes, such as in the production of biofuels. The organism's ability to degrade lignocellulosic biomass through enzyme production can facilitate the conversion of agricultural waste into fermentable sugars, which can then be transformed into bioethanol. Overall, Streptomyces gelaticus holds promise in pharmaceutical development, biofuel production, and waste treatment, making it a versatile microorganism with multiple industrial applications.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	google/gemini-flash-1.5	anthropic/claude-3.5-sonnet	google/gemini-pro-1.5	google/palm-2-chat-bison-32k	meta-llama/llama-3-70b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	anthropic/claude-3-haiku:beta	google/gemma-7b-it	openchat/openchat-7b	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mistral-7b-instruct	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	openai/gpt-4	openai/gpt-4	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	google/gemini-pro	google/gemini-pro	perplexity/llama-3-sonar-small-32k-chat	perplexity/llama-3-sonar-small-32k-chat
Motility	FALSE	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain variable ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	facultatively anaerobic ✗	facultatively anaerobic ✗	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	false ✓	true ✗	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗
Biofilm formation	N/A	true	true	true	true	true	true	true	true	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 3 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	false	false	true	true	false	true	true	true	false	true	false	false	false	true	true	false	false	false	false	true	true	true	true	true	true
Host association	FALSE	true ✗	true ✗	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Hemolysis	N/A	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	tail	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗

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