Micromonospora lupini

General Information

Micromonospora lupini is a fascinating microorganism belonging to the genus Micromonospora. This bacterium is particularly interesting due to its ability to form symbiotic relationships with plants, specifically lupins. It is known for its role in biological nitrogen fixation, which is a critical process for converting atmospheric nitrogen into a form that plants can utilize for growth. This makes M. lupini valuable in agricultural settings, especially in sustainable farming practices where reducing the need for chemical fertilizers is a priority. One of the unique aspects of Micromonospora lupini is its production of bioactive compounds. These compounds have potential applications in pharmaceuticals, including antibiotics and anti-cancer agents. The genus Micromonospora is well-known for its secondary metabolites, and M. lupini is no exception, contributing to the discovery of new drugs and therapeutic agents. Additionally, M. lupini has been studied for its genomic characteristics, which provide insights into its metabolic pathways and symbiotic mechanisms. The genome of M. lupini reveals genes involved in plant-microbe interactions, stress responses, and the synthesis of secondary metabolites. This genomic information is invaluable for biotechnological applications and for understanding the evolutionary adaptations that enable its symbiotic lifestyle. In summary, Micromonospora lupini is a microorganism of significant interest due to its symbiotic relationship with plants, nitrogen-fixing capabilities, and production of bioactive compounds. Its potential applications in agriculture and medicine make it a valuable subject of ongoing research.

Micromonospora lupini is a fascinating actinobacterium that has garnered attention due to its unique ecological niche and potential biotechnological applications. This microorganism is primarily isolated from the rhizosphere of Lupinus species, particularly in leguminous plants, which highlights its role in plant-microbe interactions and soil health. Its ability to thrive in such environments suggests a symbiotic relationship that may enhance nutrient availability for plants, particularly nitrogen fixation. One of the most interesting aspects of Micromonospora lupini is its production of bioactive compounds, including antibiotics and other secondary metabolites. These compounds have been shown to exhibit antimicrobial properties, making this organism a valuable candidate for pharmaceutical research. The potential for discovering novel antibiotics from Micromonospora lupini is particularly significant in the context of rising antibiotic resistance, as it may lead to the development of new therapeutic agents. Additionally, Micromonospora lupini is known for its ability to degrade complex organic materials, which positions it as a potential player in bioremediation efforts. This characteristic not only contributes to environmental sustainability but also opens avenues for research into the mechanisms of biodegradation and the development of bioprocesses for waste management. Overall, Micromonospora lupini stands out as a microorganism of interest due to its ecological significance, potential for antibiotic discovery, and capabilities in bioremediation, making it a valuable subject for further research in microbiology and biotechnology.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Micromonosporales

Family: Micromonosporaceae

Genus: Micromonospora

Species: Micromonospora lupini

NCBI ID

285679

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCF/026/342/015/GCF_026342015.1_ASM2634201v1

File for sequence-based predictions:
GCF_026342015.1_ASM2634201v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Micromonospora lupini is a member of the actinobacteria group and has garnered attention for its potential clinical implications. It is primarily known for its role in the environment, particularly in soil and plant interactions, but its relevance in human health is emerging. Clinical studies have indicated that Micromonospora lupini can produce bioactive compounds, which may have therapeutic potential, including antimicrobial properties. This suggests a possible role in the development of new antibiotics or antimicrobial agents to combat resistant pathogens. In terms of pathogenicity, there is limited documentation of Micromonospora lupini being directly associated with human infections. However, its close relatives in the Micromonospora genus have been implicated in various infections, particularly in immunocompromised individuals. This raises questions about the potential for opportunistic infections, although specific cases involving M. lupini remain under-researched. Furthermore, the organism's ability to produce secondary metabolites may also indicate a role in immune evasion strategies, although detailed mechanisms are not well-characterized. The exploration of its metabolites could lead to insights into how it interacts with the human immune system. Overall, while Micromonospora lupini is not currently recognized as a major pathogen, its potential for antimicrobial resistance and therapeutic applications makes it a subject of interest in microbiological and pharmaceutical research. Continued investigation into its properties and interactions with human health is warranted to fully understand its clinical relevance.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Micromonospora lupini is a species of actinobacteria commonly found in soil environments and associated with leguminous plants, particularly in the genus Lupinus. This microorganism thrives in nutrient-rich soils that are often characterized by a high organic matter content, which supports its growth and metabolic activities. Soil Biome: In the soil biome, Micromonospora lupini plays a crucial role in the decomposition of organic materials, contributing to nutrient cycling. It is known for its ability to degrade complex organic compounds, thus enhancing soil fertility and structure. The presence of this microorganism can improve the availability of nutrients for plants, particularly in agricultural settings where leguminous crops are cultivated. Symbiotic Relationships: This actinobacterium is often found in close association with the roots of Lupinus species, where it may engage in mutualistic interactions. These relationships can enhance the plant's growth by promoting nutrient uptake and providing protection against soil-borne pathogens. The interaction between Micromonospora lupini and its host plants exemplifies the importance of microbial communities in plant health and soil ecology. Environmental Adaptations: Micromonospora lupini exhibits adaptations that allow it to thrive in various soil conditions, including alkaline and acidic soils. Its metabolic versatility enables it to utilize a range of substrates, making it a resilient inhabitant of diverse terrestrial ecosystems. This adaptability is crucial for its survival in fluctuating environmental conditions, such as changes in moisture and temperature. In summary, Micromonospora lupini is an essential component of the soil biome, contributing to nutrient cycling, engaging in beneficial symbiotic relationships with leguminous plants, and demonstrating remarkable environmental adaptability.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Micromonospora lupini has shown significant potential in various industrial applications. One of the most notable areas is in biotechnology, where it is utilized for its ability to produce a range of bioactive compounds, including antibiotics. This makes Micromonospora lupini a valuable organism in the development of new pharmaceuticals, particularly in the fight against antibiotic-resistant bacteria. The organism's fermentation processes are crucial for the extraction and production of these compounds, allowing for the development of novel therapeutic agents. In the realm of waste management, Micromonospora lupini has demonstrated capabilities in biodegradation, particularly in the breakdown of complex organic materials. This property can be harnessed in bioremediation efforts, where the microorganism is employed to clean up contaminated environments, such as soil and water, by degrading pollutants and organic waste. Additionally, Micromonospora lupini has potential applications in biofuel production. Its metabolic pathways can be exploited to convert biomass into biofuels through fermentation processes, contributing to sustainable energy solutions. The efficiency of this microorganism in breaking down lignocellulosic materials makes it a candidate for enhancing biofuel yield. Overall, Micromonospora lupini stands out as a versatile microorganism with applications spanning pharmaceutical development, biotechnology, waste management, and biofuel production, showcasing its importance in various industrial sectors.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	openai/gpt-3.5-turbo-0125	anthropic/claude-3.5-sonnet	meta-llama/llama-3-70b-instruct:nitro	google/gemini-pro	anthropic/claude-3-haiku:beta	perplexity/llama-3-sonar-small-32k-chat	google/gemma-7b-it	openchat/openchat-7b	mistralai/mixtral-8x7b-instruct:nitro	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	openai/gpt-4	openai/gpt-4	google/gemini-flash-1.5	google/gemini-flash-1.5	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	meta-llama/llama-3-8b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	mistralai/mistral-7b-instruct	mistralai/mistral-7b-instruct
Motility	FALSE	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain positive ✓
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗
Biofilm formation	N/A	true	true	false	true	true	true	true	false	true	true	true	false	false	true	true	false	false	true	true	true	true	true	true	false	false	false	false
Animal pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	false	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false	false	false
Host association	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗
Plant pathogenicity	FALSE	false ✓	false ✓	true ✗	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓
Hemolysis	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	gamma	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	N/A	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	coccus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	coccus	coccus	bacillus	bacillus

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