Streptomyces coriariae

General Information

Streptomyces coriariae is a fascinating microorganism belonging to the genus Streptomyces, which is renowned for its prolific production of secondary metabolites. One of the most notable characteristics of S. coriariae is its ability to produce a wide array of bioactive compounds, including antibiotics, antifungals, and antitumor agents. This makes it an invaluable resource in pharmaceutical research and biotechnology. Streptomyces species are known for their complex life cycle, which includes the formation of a mycelium and spore chains, contributing to their adaptability and survival in various environments. S. coriariae is no exception and exhibits a robust ability to thrive in diverse ecological niches, often isolated from soil samples. The metabolic versatility of S. coriariae is another key feature, enabling it to degrade a variety of organic materials. This trait is particularly interesting for environmental applications, such as bioremediation, where it can be employed to break down pollutants and recycle nutrients in the soil. In addition to its practical applications, S. coriariae is also of significant interest in basic scientific research. Its genome harbors numerous gene clusters responsible for the biosynthesis of its diverse secondary metabolites. Studying these gene clusters can provide insights into the genetic and enzymatic pathways involved in natural product synthesis, potentially leading to the discovery of novel compounds with therapeutic potential. Overall, Streptomyces coriariae stands out as a microorganism of great interest due to its prolific production of bioactive compounds, metabolic versatility, and potential applications in medicine and environmental science.

Streptomyces coriariae is a fascinating actinobacterium known for its remarkable ability to produce a variety of bioactive compounds, making it a valuable organism in pharmaceutical research. This species is part of the larger genus Streptomyces, which is renowned for its role in natural antibiotic production. What sets S. coriariae apart is its unique metabolic pathways that allow it to synthesize novel secondary metabolites, which have potential applications in medicine and agriculture. One of the most interesting aspects of S. coriariae is its ability to thrive in diverse environments, particularly in soil rich in organic matter. This adaptability not only contributes to its ecological significance but also enhances its potential for biotechnological applications. Researchers are particularly interested in the genetic and enzymatic mechanisms that enable S. coriariae to produce these compounds, as understanding these processes could lead to the discovery of new drugs. Additionally, S. coriariae has been studied for its role in bioremediation, where its metabolic capabilities can be harnessed to degrade environmental pollutants. This characteristic underscores its potential utility in addressing environmental challenges. Overall, the unique biosynthetic capabilities and ecological versatility of Streptomyces coriariae make it a subject of significant interest in microbiology and biotechnology.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Kitasatosporales

Family: Streptomycetaceae

Genus: Streptomyces

Species: Streptomyces coriariae

NCBI ID

2864460

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/913/919/575/GCA_913919575.1_CMBFB

File for sequence-based predictions:
GCA_913919575.1_CMBFB_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Streptomyces coriariae is a member of the genus Streptomyces, which is known for its significant role in the production of antibiotics and other bioactive compounds. While S. coriariae itself is not widely recognized as a human pathogen, its relatives have been implicated in various infections and have clinical relevance due to their potential to produce antimicrobial agents. Clinical implications of S. coriariae include its potential use in the development of novel therapeutics, particularly in the fight against antibiotic-resistant bacteria. The genus Streptomyces is known for its complex life cycle and ability to produce a wide array of secondary metabolites, which can have profound effects on human health. Some species are utilized in probiotics and have been studied for their beneficial effects on gut health. However, the specific interactions of S. coriariae with the human microbiome and its immune system are not well-documented. In terms of immune evasion strategies, while S. coriariae may not exhibit pathogenicity, understanding the mechanisms of its relatives can provide insights into how these organisms survive in hostile environments, including the human body. Overall, while Streptomyces coriariae may not be directly associated with specific diseases or outbreaks, its potential in therapeutics and the broader implications of the Streptomyces genus in medicine underscore its relevance in clinical microbiology.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Streptomyces coriariae is a species of actinobacteria commonly found in soil and decaying organic matter. This microorganism thrives in a variety of terrestrial biomes, particularly in regions with rich nutrient availability and moisture. Its ecological niche is primarily associated with the decomposition of organic materials, where it plays a crucial role in nutrient cycling and soil health. Soil Ecosystems: In soil environments, Streptomyces coriariae contributes to the breakdown of complex organic compounds, facilitating the release of nutrients that are essential for plant growth. This process not only enriches the soil but also supports a diverse community of microorganisms, creating a balanced ecosystem. Symbiotic Relationships: This bacterium is known for its ability to form symbiotic relationships with various plants. It can enhance plant growth by producing phytohormones and other beneficial compounds, which promote root development and increase resistance to pathogens. Such interactions underscore its importance in agricultural ecosystems, where it can be utilized as a natural biofertilizer. Adaptation to Environmental Conditions: Streptomyces coriariae exhibits remarkable adaptability to varying environmental conditions, including changes in pH, temperature, and moisture levels. This adaptability allows it to thrive in diverse habitats, from temperate forests to tropical regions, making it a versatile organism in the microbial world. In summary, Streptomyces coriariae is a vital component of soil ecosystems, contributing to nutrient cycling, supporting plant health through symbiotic relationships, and demonstrating adaptability to various environmental conditions.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Streptomyces coriariae is known for its significant contributions to various industrial applications, particularly in the fields of biotechnology, pharmaceutical development, and waste management. This actinobacterium is recognized for its ability to produce a range of bioactive compounds, including antibiotics, which are crucial in the development of new medications. Its role in fermentation processes allows for the production of these valuable metabolites, making it a key player in the pharmaceutical industry. In addition to its pharmaceutical applications, Streptomyces coriariae has demonstrated potential in biodegradation processes, where it can break down complex organic materials, thus contributing to waste treatment and environmental remediation efforts. This capability is particularly important in managing waste from agricultural and industrial sources, where the breakdown of pollutants can lead to cleaner ecosystems. Moreover, the enzymatic activities of Streptomyces coriariae are being explored for their potential in biofuel production. The organism can produce enzymes that facilitate the breakdown of lignocellulosic biomass, which is a critical step in the conversion of plant materials into fermentable sugars for bioethanol production. This positions Streptomyces coriariae as a valuable asset in the pursuit of sustainable energy solutions. Overall, the diverse applications of Streptomyces coriariae in fermentation, biodegradation, and enzyme production highlight its importance in advancing industrial biotechnology and environmental sustainability.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	google/gemini-flash-1.5	google/gemini-pro-1.5	anthropic/claude-3.5-sonnet	google/palm-2-chat-bison-32k	meta-llama/llama-3-70b-instruct:nitro	google/gemini-pro	meta-llama/llama-3-8b-instruct:nitro	anthropic/claude-3-haiku:beta	openchat/openchat-7b	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	perplexity/llama-3-sonar-small-32k-chat	perplexity/llama-3-sonar-small-32k-chat	google/gemma-7b-it	google/gemma-7b-it	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mistral-7b-instruct	mistralai/mistral-7b-instruct
Motility	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain variable ✗
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	true ✗	true ✗	false ✓	true ✗	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗
Biofilm formation	N/A	true	true	true	true	true	true	true	true	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	N/A	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	true	true	false	false	false	false	false	false
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 3 ✗	biosafety level 3 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	false	true	false	true	false	true	true	true	false	false	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false
Host association	FALSE	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓
Spore formation	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Hemolysis	N/A	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	tail	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗

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