Streptomyces longhuiensis

General Information

Streptomyces longhuiensis is a fascinating microorganism belonging to the genus Streptomyces, which is renowned for its prolific production of bioactive compounds. This species was first isolated from soil, a common habitat for many Streptomyces species, which are known for their complex life cycles and ability to produce a wide array of secondary metabolites. One of the most noteworthy characteristics of Streptomyces longhuiensis is its potential in the field of natural product discovery. Members of the Streptomyces genus are responsible for the production of over two-thirds of the clinically useful antibiotics of natural origin, and S. longhuiensis is no exception. It has been identified as a producer of several novel compounds with potential pharmaceutical applications. Additionally, Streptomyces longhuiensis exhibits a unique morphological differentiation, forming a mycelium that can differentiate into spores. This complex life cycle is not only interesting from a biological standpoint but also provides insights into the development and regulation of secondary metabolism, which is often linked to the organism's developmental stages. From a research perspective, the study of Streptomyces longhuiensis can contribute to a better understanding of the genetic and biochemical pathways involved in the synthesis of antibiotics and other secondary metabolites. This knowledge is crucial for the development of new drugs, especially in the face of rising antibiotic resistance. In summary, Streptomyces longhuiensis is a valuable microorganism for scientific research due to its ability to produce novel bioactive compounds, its complex life cycle, and its potential contributions to the field of natural product chemistry and drug discovery.

Streptomyces longhuiensis is a fascinating actinobacterium that was first isolated from soil samples in Longhui County, Hunan Province, China. This organism is particularly noteworthy due to its ability to produce a diverse array of bioactive compounds, which makes it a valuable resource in pharmaceutical research. The genus Streptomyces is renowned for its role in the production of over two-thirds of naturally derived antibiotics, and S. longhuiensis contributes to this legacy with its unique metabolic capabilities. One of the most interesting aspects of S. longhuiensis is its potential for antimicrobial activity. Research has indicated that it produces several secondary metabolites that exhibit significant antibacterial and antifungal properties. This characteristic positions S. longhuiensis as a promising candidate for the discovery of new therapeutic agents, especially in the face of rising antibiotic resistance. Additionally, the genomic analysis of S. longhuiensis has revealed a rich biosynthetic gene cluster repertoire, suggesting that this organism may be capable of synthesizing novel compounds that have yet to be characterized. This genetic diversity not only enhances its potential for drug discovery but also provides insights into the evolutionary adaptations of soil-dwelling microorganisms. Furthermore, the ecological role of S. longhuiensis in soil environments is of great interest. As a member of the Streptomyces genus, it likely participates in the degradation of organic matter and contributes to nutrient cycling, which is essential for maintaining soil health. Understanding its ecological interactions can shed light on the complex relationships within microbial communities. In summary, Streptomyces longhuiensis stands out due to its bioactive compound production, genomic potential for novel drug discovery, and its ecological significance in soil ecosystems, making it a valuable subject for ongoing research in microbiology and biotechnology.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Kitasatosporales

Family: Streptomycetaceae

Genus: Streptomyces

Species: Streptomyces longhuiensis

NCBI ID

2880933

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/020/616/555/GCA_020616555.1_ASM2061655v1

File for sequence-based predictions:
GCA_020616555.1_ASM2061655v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Streptomyces longhuiensis is a member of the genus Streptomyces, which is known for its significant role in the production of antibiotics and other bioactive compounds. While specific clinical implications of Streptomyces longhuiensis are still being explored, its relatives have been extensively studied for their antimicrobial properties. This organism may contribute to the development of new therapeutics against various bacterial infections, particularly in the context of rising antimicrobial resistance seen in many pathogens today. In terms of human health, members of the Streptomyces genus are often found in soil and are not typically associated with pathogenicity in humans. However, they can occasionally be implicated in opportunistic infections, especially in immunocompromised individuals. The potential for Streptomyces longhuiensis to produce novel compounds could lead to advancements in probiotics or other beneficial applications in microbiome research. Furthermore, the ability of Streptomyces species to evade the immune response through various mechanisms, such as the production of secondary metabolites, highlights their complex interactions with the human body. Continued research into Streptomyces longhuiensis may uncover more about its role in disease associations and its potential as a source of new drugs, particularly in the fight against resistant bacterial strains.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Streptomyces longhuiensis is a species of actinobacteria that is primarily associated with soil ecosystems and decaying organic matter. This microorganism thrives in nutrient-rich environments, particularly in areas where organic material is abundant, such as forest floors and agricultural soils. Its ability to decompose complex organic compounds makes it a vital player in nutrient cycling within these biomes. In its natural habitat, Streptomyces longhuiensis engages in decomposition, breaking down dead plant and animal matter, which contributes to soil fertility and structure. This process not only recycles nutrients but also enhances the microbial diversity of the soil, creating a more resilient ecosystem. Additionally, Streptomyces longhuiensis is known for its role in antibiotic production, which can inhibit the growth of competing microorganisms. This characteristic allows it to establish a niche in competitive environments, where it can thrive by suppressing potential pathogens. Its interactions with other soil microbes can lead to symbiotic relationships, where it may provide benefits to plants through enhanced nutrient availability while receiving organic carbon in return. Overall, the ecological role of Streptomyces longhuiensis in terrestrial biomes is significant, as it contributes to both the health of the soil and the overall functioning of the ecosystem.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Streptomyces longhuiensis has shown significant potential in various industrial applications due to its unique metabolic capabilities. One of the most notable areas is in biotechnology, where Streptomyces longhuiensis is utilized for its ability to produce a wide range of bioactive compounds, including antibiotics and enzymes. This makes it a valuable organism in the development of new pharmaceuticals, particularly in the search for novel antimicrobial agents. In the realm of waste management, Streptomyces longhuiensis has demonstrated effective biodegradation capabilities, particularly in the breakdown of complex organic pollutants. This property is crucial for the treatment of contaminated environments, as it can help in the remediation of soil and water by degrading harmful substances. Furthermore, the organism is also being explored for its role in biofuel production. Through fermentation processes, Streptomyces longhuiensis can contribute to the conversion of biomass into biofuels, enhancing the efficiency of biofuel production systems. Overall, the diverse enzymatic activities and metabolic pathways of Streptomyces longhuiensis position it as a promising candidate in various industries, including pharmaceutical development, biotechnology, and environmental management, making it a key player in the advancement of sustainable industrial practices.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 8

LLM predicted phenotypes: 5

Phenotype	High-quality annotation	anthropic/claude-3.5-sonnet	google/gemini-flash-1.5	google/gemini-flash-1.5	meta-llama/llama-3-70b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	anthropic/claude-3-haiku:beta	perplexity/llama-3-sonar-small-32k-chat	google/gemma-7b-it	openchat/openchat-7b	microsoft/phi-3-mini-128k-instruct	mistralai/mistral-7b-instruct	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mixtral-8x7b-instruct:nitro	google/gemini-pro	google/gemini-pro
Motility	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	N/A	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Biofilm formation	N/A	true	true	true	true	true	true	true	true	true	true	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	N/A	false	false	false	false	false	false	false	true	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 3 ✗	biosafety level 2 ✗	biosafety level 3 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	false	false	false	true	true	true	true	true	true	true	false	false	false	true	true	true	true	true	true	false	false	true	true	true	true	true	true
Host association	N/A	true	true	true	true	true	false	true	false	true	false	true	false	false	false	false	false	false	false	false	false	false	true	true	true	true	true	true
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Hemolysis	N/A	N/A	gamma	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	tail	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗

Back to Search