Streptomyces guryensis

General Information

Streptomyces guryensis is a fascinating microorganism belonging to the genus Streptomyces, which is renowned for its prolific production of bioactive compounds. One of the most notable characteristics of S. guryensis is its ability to produce a wide array of secondary metabolites, many of which have significant pharmaceutical applications. These metabolites include antibiotics, antifungals, and antitumor agents, making S. guryensis a valuable resource in drug discovery and development. Streptomyces species are also known for their complex life cycle, which includes the formation of a mycelium and spore chains. This complex differentiation process is of great interest to researchers studying bacterial development and gene regulation. The genetic and metabolic pathways involved in the production of secondary metabolites in S. guryensis are a key area of research, as understanding these pathways can lead to the discovery of new drugs and the improvement of existing ones. Additionally, S. guryensis has been studied for its potential in bioremediation. The organism's ability to degrade various environmental pollutants highlights its ecological importance and potential utility in cleaning up contaminated environments. The combination of its pharmaceutical potential and environmental applications makes Streptomyces guryensis a particularly valuable and intriguing subject for scientific research.

Streptomyces guryensis is a fascinating actinobacterium known for its remarkable ability to produce a diverse array of bioactive compounds, including antibiotics and antifungal agents. This species is part of the larger genus Streptomyces, which is renowned for its role in natural product discovery and pharmaceutical applications. What makes S. guryensis particularly interesting is its unique metabolic pathways that allow it to synthesize compounds with potential therapeutic properties. One of the standout features of S. guryensis is its ability to thrive in various environmental conditions, which contributes to its versatility in producing secondary metabolites. This adaptability not only enhances its survival but also increases the likelihood of discovering novel compounds that could lead to new drug development. Research has shown that the metabolites produced by S. guryensis exhibit significant antimicrobial activity, making it a valuable organism in the search for new antibiotics in an era of rising antibiotic resistance. Furthermore, the genomic analysis of S. guryensis has revealed a rich repertoire of biosynthetic gene clusters, indicating its potential to produce a wide range of secondary metabolites. This genetic diversity is a treasure trove for researchers interested in natural product chemistry and drug discovery. The ongoing studies on S. guryensis not only enhance our understanding of microbial ecology but also pave the way for innovative approaches in biotechnology and medicine. Overall, Streptomyces guryensis stands out as a significant player in the field of microbiology, with promising implications for future research and applications.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Kitasatosporales

Family: Streptomycetaceae

Genus: Streptomyces

Species: Streptomyces guryensis

NCBI ID

2886947

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/021/261/325/GCA_021261325.1_ASM2126132v1

File for sequence-based predictions:
GCA_021261325.1_ASM2126132v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Streptomyces guryensis is a member of the genus Streptomyces, which is known for its significant role in the production of antibiotics and other bioactive compounds. While S. guryensis itself is not widely recognized for direct pathogenicity in humans, its relatives are often associated with various clinical implications. Antibiotic production is one of the most notable aspects of this genus, with many species contributing to the development of clinically important antibiotics such as streptomycin and tetracycline. This highlights the potential of S. guryensis in therapeutics and the pharmaceutical industry. In terms of immune response, members of the Streptomyces genus can interact with the human microbiome, potentially influencing health through the modulation of the immune system. However, the specific interactions of S. guryensis with human health are not well-documented, and further research is needed to elucidate its role in human health. Moreover, the genus is known for its ability to produce a variety of secondary metabolites, which may have implications in antimicrobial resistance. The emergence of resistance mechanisms in bacteria can be influenced by the presence of antibiotic-producing organisms, including Streptomyces species. Understanding these dynamics is crucial for addressing the challenges posed by antimicrobial resistance in clinical settings. Overall, while Streptomyces guryensis may not be directly associated with specific diseases or infections, its contributions to antibiotic production and potential interactions with the human microbiome underscore its relevance in the fields of microbiology and pharmacology.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Streptomyces guryensis is a species of actinobacteria that is primarily found in soil ecosystems and decaying organic matter. This microorganism thrives in environments rich in organic material, where it plays a crucial role in the decomposition process. Its ability to break down complex organic compounds contributes significantly to nutrient cycling within these biomes. Soil Biomes: In soil, Streptomyces guryensis is often associated with the rhizosphere, the region of soil directly influenced by plant roots. Here, it engages in nutrient exchange and can promote plant growth through the production of growth-promoting substances. This interaction exemplifies a form of symbiosis, where both the microorganism and the plant benefit from their relationship. Decaying Organic Matter: In environments characterized by decaying plant material, Streptomyces guryensis contributes to the breakdown of cellulose and lignin, essential processes in the decomposition of plant matter. This activity not only aids in the recycling of nutrients back into the soil but also helps in the formation of humus, which is vital for soil health and fertility. Additionally, Streptomyces guryensis is known for its ability to produce a variety of antibiotics and other bioactive compounds, which can inhibit the growth of competing microorganisms. This characteristic allows it to establish a niche in its habitat, often leading to a competitive advantage in nutrient-rich environments. Overall, Streptomyces guryensis is an integral component of its ecosystems, contributing to both the health of the soil and the overall functioning of the ecological community.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Streptomyces guryensis has shown significant potential in various industrial applications due to its unique metabolic capabilities. One of the most notable areas is in biotechnology, where Streptomyces guryensis is utilized for its ability to produce a wide range of bioactive compounds, including antibiotics and enzymes. This organism is particularly valuable in the fermentation process, where it can be harnessed to synthesize secondary metabolites that have pharmaceutical importance. In the realm of waste management, Streptomyces guryensis has demonstrated effective biodegradation capabilities, particularly in the breakdown of complex organic pollutants. This makes it a candidate for bioremediation strategies aimed at cleaning up contaminated environments, such as soil and water bodies affected by industrial waste. Furthermore, the organism's enzymatic activity is crucial in biofuel production, where it can be involved in the conversion of biomass into fermentable sugars through enzyme production. These sugars can then be fermented by other microorganisms to produce bioethanol, contributing to sustainable energy solutions. Overall, Streptomyces guryensis exemplifies the versatility of actinobacteria in various industries, particularly in pharmaceutical development, biotechnology, and environmental management, showcasing its potential to contribute to both economic and ecological sustainability.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	anthropic/claude-3.5-sonnet	google/gemini-flash-1.5	google/gemini-flash-1.5	meta-llama/llama-3-70b-instruct:nitro	google/gemini-pro	anthropic/claude-3-haiku:beta	perplexity/llama-3-sonar-small-32k-chat	google/gemma-7b-it	openchat/openchat-7b	mistralai/mixtral-8x7b-instruct:nitro	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	openai/gpt-4	openai/gpt-4	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	meta-llama/llama-3-8b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	mistralai/mistral-7b-instruct	mistralai/mistral-7b-instruct
Motility	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗
Gram staining	gram stain positive	gram stain positive ✓	N/A	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain variable ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	facultatively anaerobic ✗	facultatively anaerobic ✗	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	true ✗	true ✗	true ✗	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗
Biofilm formation	N/A	true	true	true	true	true	true	true	true	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false
Animal pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 3 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	N/A	N/A
Health association	N/A	true	false	false	true	true	true	true	true	true	true	false	false	false	false	true	true	true	true	false	false	true	true	true	true	true	true	false	false
Host association	FALSE	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Plant pathogenicity	N/A	false	false	false	false	false	false	false	true	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false
Spore formation	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Hemolysis	N/A	N/A	gamma	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	tail	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗

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