Corynebacterium meitnerae

General Information

Corynebacterium meitnerae is a fascinating microorganism that belongs to the genus Corynebacterium. This genus is known for its diverse range of species, many of which have significant roles in both medical and industrial contexts. What makes C. meitnerae particularly interesting is its potential for biotechnological applications and its unique genetic makeup. One of the key characteristics of C. meitnerae is its ability to thrive in various environments, which suggests a high level of adaptability. This adaptability can be leveraged in bioremediation processes, where microorganisms are used to clean up contaminated environments. Additionally, the metabolic pathways of C. meitnerae are of great interest to researchers, as they may offer insights into novel biochemical processes that could be harnessed for industrial applications, such as the production of biofuels or bioplastics. From a genetic perspective, C. meitnerae possesses unique sequences that differentiate it from other members of the Corynebacterium genus. These genetic markers are valuable for phylogenetic studies, helping scientists understand the evolutionary relationships within this diverse group of bacteria. Moreover, the genome of C. meitnerae may contain genes that encode for enzymes with unique properties, which could be exploited in various biotechnological processes. In summary, Corynebacterium meitnerae stands out due to its biotechnological potential, environmental adaptability, and unique genetic features. These characteristics make it a valuable subject for ongoing research and potential industrial applications.

Corynebacterium meitnerae is a fascinating species within the genus Corynebacterium, notable for its unique biochemical properties and ecological significance. This organism is primarily recognized for its ability to degrade complex organic compounds, which positions it as a potential candidate for bioremediation applications. Its metabolic versatility allows it to thrive in diverse environments, including soil and water, where it plays a crucial role in nutrient cycling. One of the most interesting aspects of Corynebacterium meitnerae is its production of specific enzymes that can break down pollutants, making it valuable for environmental cleanup efforts. Researchers are particularly interested in its enzymatic pathways, which could lead to the development of novel biotechnological applications aimed at waste management and pollution reduction. Additionally, Corynebacterium meitnerae has been studied for its interactions with other microorganisms in its habitat. These interactions can provide insights into microbial community dynamics and the role of Corynebacterium species in maintaining ecological balance. The organism's ability to form symbiotic relationships with plants and other microbes further enhances its importance in agricultural and ecological research. In summary, Corynebacterium meitnerae stands out due to its biodegradative capabilities, metabolic diversity, and ecological interactions, making it a valuable subject for ongoing research in microbiology and environmental science.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Mycobacteriales

Family: Corynebacteriaceae

Genus: Corynebacterium

Species: Corynebacterium meitnerae

NCBI ID

2913498

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCF/027/570/075/GCF_027570075.1_ASM2757007v1

File for sequence-based predictions:
GCF_027570075.1_ASM2757007v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Corynebacterium meitnerae is a member of the genus Corynebacterium, which includes several species known for their clinical significance. While Corynebacterium meitnerae itself is less commonly discussed in clinical literature, it is important to consider its potential implications in human health. Corynebacterium species are often associated with opportunistic infections, particularly in immunocompromised individuals. This organism may be involved in skin infections, respiratory infections, and wound infections, although specific cases of Corynebacterium meitnerae infections are rare and not well-documented. One of the notable aspects of Corynebacterium species is their ability to exhibit antimicrobial resistance, particularly to common antibiotics. This resistance can complicate treatment options for infections caused by these organisms. The mechanisms of resistance may include the production of beta-lactamases and alterations in target sites, which can lead to treatment failures. In terms of immune evasion, Corynebacterium species can produce various virulence factors that help them survive in the host environment. These may include the ability to form biofilms, which protect the bacteria from both the host immune response and antibiotic treatment. While Corynebacterium meitnerae has not been directly linked to any major outbreaks, its presence in clinical specimens should not be overlooked, especially in patients with underlying health conditions. Further research is needed to fully understand the clinical implications of this organism and its potential role in human disease.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Corynebacterium meitnerae is a species of bacteria that is primarily associated with the human microbiome, particularly in the skin and mucosal surfaces of the body. This organism thrives in environments that are rich in organic material and moisture, making it well-suited for colonization in areas such as the axillary region, groin, and other skin folds where sweat and sebum are prevalent. In these habitats, Corynebacterium meitnerae plays a crucial role in maintaining the balance of the microbial community. It contributes to the skin's natural flora, which helps to protect against pathogenic organisms by competing for resources and producing antimicrobial substances. This symbiotic relationship is essential for the overall health of the skin, as it aids in the prevention of infections and supports the immune system. Furthermore, Corynebacterium meitnerae has shown adaptability to varying environmental conditions, including changes in pH and temperature, which allows it to thrive in diverse microhabitats within the human body. Its presence is often linked to the breakdown of lipids and proteins, contributing to the metabolic processes that are vital for skin health. Overall, the ecological niche of Corynebacterium meitnerae is characterized by its interactions with the host, its role in microbial diversity, and its ability to adapt to the unique conditions of the human skin environment.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Corynebacterium meitnerae has shown potential in various industrial applications, particularly in the fields of biotechnology and waste management. This organism is known for its ability to participate in fermentation processes, which can be harnessed for the production of valuable metabolites such as amino acids and organic acids. For instance, Corynebacterium meitnerae can be utilized in the fermentation of sugars to produce L-lysine, an essential amino acid widely used in animal feed and human nutrition. In the realm of waste management, Corynebacterium meitnerae has demonstrated capabilities in biodegradation, particularly in the breakdown of complex organic compounds. This property can be leveraged for the treatment of industrial effluents, helping to reduce environmental pollution and recover valuable resources from waste streams. Moreover, the enzymatic activity of Corynebacterium meitnerae can be explored for enzyme production, which is crucial in various industrial processes, including food processing and bioremediation. The organism's ability to produce specific enzymes can facilitate the breakdown of pollutants, making it a candidate for applications in bioremediation efforts aimed at cleaning contaminated sites. Overall, Corynebacterium meitnerae presents a promising avenue for innovation in biotechnology, waste management, and pharmaceutical development, with its unique metabolic capabilities paving the way for sustainable industrial practices.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 8

LLM predicted phenotypes: 5

Phenotype	High-quality annotation	meta-llama/llama-3-8b-instruct:nitro	mistralai/mixtral-8x7b-instruct:nitro	anthropic/claude-3.5-sonnet	google/palm-2-chat-bison-32k	perplexity/llama-3-sonar-small-32k-chat	google/gemma-7b-it	mistralai/mistral-7b-instruct	google/gemini-pro	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	openai/gpt-4	openai/gpt-4	google/gemini-flash-1.5	google/gemini-flash-1.5	anthropic/claude-3-haiku:beta	anthropic/claude-3-haiku:beta	meta-llama/llama-3-70b-instruct:nitro	meta-llama/llama-3-70b-instruct:nitro	openchat/openchat-7b	openchat/openchat-7b	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b
Motility	FALSE	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain positive	gram stain negative ✗	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain variable ✗	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓
Aerophilicity	aerobic	aerotolerant ✗	facultatively anaerobic ✗	N/A	N/A	N/A	N/A	N/A	N/A	facultatively anaerobic ✗	facultatively anaerobic ✗	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	aerotolerant ✗	aerotolerant ✗	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Biofilm formation	N/A	true	true	true	true	true	true	false	true	true	true	true	true	true	true	false	false	true	true	true	true	true	true	false	false	true	true	true	true
Animal pathogenicity	N/A	false	false	false	true	true	true	false	true	false	false	false	false	true	true	false	false	true	true	true	true	false	false	false	false	false	false	true	true
Biosafety level	biosafety level 1	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗
Health association	N/A	true	true	true	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false	true	true
Host association	N/A	true	true	true	true	true	false	true	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false	true	true
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	gamma ✓	gamma ✓	N/A	N/A	N/A	N/A	beta ✗	beta ✗	alpha ✗	alpha ✗	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	N/A	bacillus	bacillus	bacillus	bacillus	coccus	bacillus	coccus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	coccus	coccus	coccus	coccus	bacillus	bacillus

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