Mycolicibacter hiberniae

General Information

Mycolicibacter hiberniae is a fascinating microorganism belonging to the genus Mycolicibacter. This genus is known for its complex and unique cell wall structure, which includes mycolic acids, contributing to its resilience and distinctive characteristics. One of the most intriguing aspects of M. hiberniae is its ability to survive in extreme environments, which makes it a subject of interest for researchers studying extremophiles and their potential applications in biotechnology and astrobiology. Notably, Mycolicibacter hiberniae has been isolated from cold environments, suggesting it possesses mechanisms for cold adaptation. This makes it a valuable model for studying psychrophilic organisms and their metabolic pathways. The organism's ability to thrive in low temperatures could provide insights into novel enzymes and biochemical processes that are stable and active at cold temperatures, which are highly sought after in industrial applications such as bioremediation and the production of cold-active enzymes. Furthermore, the genus Mycolicibacter is closely related to Mycobacterium, which includes significant pathogens like Mycobacterium tuberculosis. Studying M. hiberniae can therefore offer comparative insights into the pathogenic mechanisms and potential vulnerabilities of related pathogenic species. This comparative approach can aid in the development of new therapeutic strategies and diagnostic tools. In summary, Mycolicibacter hiberniae is a microorganism of considerable interest due to its extreme environment adaptability, potential biotechnological applications, and its relevance to understanding pathogenic relatives. Its unique characteristics make it a valuable subject for ongoing and future research endeavors.

Mycolicibacter hiberniae is a fascinating species within the genus Mycolicibacter, which is known for its unique lipid composition and ecological versatility. This microorganism is particularly interesting due to its ability to thrive in cold environments, which has implications for understanding microbial life in extreme conditions. The presence of mycolic acids in its cell wall contributes to its resilience and adaptability, allowing it to survive in low-temperature habitats. One of the most valuable aspects of M. hiberniae is its potential role in biogeochemical cycles, particularly in the degradation of organic matter in cold ecosystems. This capability makes it a subject of interest for researchers studying carbon cycling and climate change impacts on microbial communities. Furthermore, its unique metabolic pathways may offer insights into novel biotechnological applications, such as bioremediation or the production of bioactive compounds. Additionally, M. hiberniae has been isolated from various environmental samples, indicating its widespread distribution and ecological significance. This adaptability to diverse habitats underscores the importance of studying this organism to better understand microbial diversity and ecosystem functioning. Overall, the study of Mycolicibacter hiberniae not only enhances our knowledge of extremophiles but also opens avenues for practical applications in environmental science and biotechnology.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Mycobacteriales

Family: Mycobacteriaceae

Genus: Mycolicibacter

Species: Mycolicibacter hiberniae

NCBI ID

29314

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/010/729/485/GCA_010729485.1_ASM1072948v1

File for sequence-based predictions:
GCA_010729485.1_ASM1072948v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Mycolicibacter hiberniae is a member of the genus Mycolicibacter, which is known for its association with various clinical implications. This microorganism has been identified as a potential pathogen, particularly in immunocompromised individuals. It is associated with infections that can lead to significant morbidity, especially in patients with underlying health conditions such as diabetes or those undergoing immunosuppressive therapy. One of the notable aspects of Mycolicibacter hiberniae is its pathogenicity, which is attributed to its ability to evade the immune response through various mechanisms, including the production of mycolic acids that contribute to its cell wall's structural integrity and resistance to phagocytosis. This characteristic allows it to persist in host tissues and complicate treatment efforts. In terms of antimicrobial resistance, Mycolicibacter hiberniae has shown resistance to several common antibiotics, which poses a challenge for effective treatment. The presence of this organism in clinical samples has raised concerns about its role in nosocomial infections and the need for improved diagnostic methods to identify it promptly. While research is ongoing, there is potential for Mycolicibacter hiberniae to be explored in the context of probiotics or other therapeutic applications, given its unique properties. However, its clinical relevance primarily lies in its association with infections and the challenges it presents in terms of treatment and management.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Mycolicibacter hiberniae has shown significant potential in various industrial applications. One of the primary areas of interest is in biotechnology, where Mycolicibacter hiberniae is utilized for its unique metabolic capabilities. This organism is known for its ability to perform fermentation, which can be harnessed for the production of valuable metabolites, including organic acids and alcohols, that are essential in the food and beverage industry. In the realm of waste management, Mycolicibacter hiberniae has demonstrated effective biodegradation properties, particularly in the breakdown of complex organic compounds. This makes it a candidate for use in bioremediation processes, where it can help in the detoxification of contaminated environments, such as soil and water, by degrading pollutants. Furthermore, the organism's enzymatic activity is of great interest in pharmaceutical development. Mycolicibacter hiberniae can produce specific enzymes that may be utilized in the synthesis of pharmaceutical compounds, enhancing the efficiency of drug production processes. Additionally, there is potential for Mycolicibacter hiberniae in biofuel production. Its metabolic pathways can be explored for the conversion of biomass into biofuels, contributing to sustainable energy solutions. The organism's ability to ferment various substrates can be optimized to increase yield and efficiency in biofuel generation. Overall, Mycolicibacter hiberniae presents a versatile platform for various industrial applications, particularly in biotechnology, waste management, pharmaceutical development, and biofuel production, showcasing its importance in advancing sustainable practices and innovative solutions in these fields.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 8

LLM predicted phenotypes: 5

Phenotype	High-quality annotation	anthropic/claude-3.5-sonnet	meta-llama/llama-3-8b-instruct:nitro	google/gemini-flash-1.5	anthropic/claude-3-haiku:beta	openchat/openchat-7b	microsoft/phi-3-mini-128k-instruct	mistralai/mixtral-8x7b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	openai/gpt-4	openai/gpt-4	meta-llama/llama-3-70b-instruct:nitro	meta-llama/llama-3-70b-instruct:nitro	google/gemma-7b-it	google/gemma-7b-it	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	mistralai/mistral-7b-instruct	mistralai/mistral-7b-instruct
Motility	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain negative ✗	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain negative ✗	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain positive ✓	N/A	gram stain variable ✗
Aerophilicity	aerobic	aerobic ✓	aerotolerant ✗	aerobic ✓	N/A	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	aerobic ✓	aerobic ✓	N/A	N/A
Extreme environment tolerance	N/A	false	true	false	true	false	false	false	true	false	false	true	true	false	false	false	false	false	false	false	false	true	true	false	false	true	true
Biofilm formation	N/A	true	true	true	true	false	true	true	true	true	true	true	true	false	false	true	true	false	false	true	true	true	true	true	true	true	true
Animal pathogenicity	TRUE	false ✗	false ✗	true ✓	false ✗	false ✗	false ✗	false ✗	true ✓	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗
Health association	N/A	false	true	true	true	false	false	true	true	false	false	true	true	true	true	true	true	false	false	true	true	true	true	true	true	false	false
Host association	N/A	false	false	true	true	false	true	true	true	false	false	true	true	true	true	false	false	false	false	true	true	false	false	true	true	false	false
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	true ✗	false ✓	true ✗	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	alpha	alpha	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓

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