Corynebacterium kalidii

General Information

Corynebacterium kalidii is a recently identified species within the genus Corynebacterium. This microorganism is particularly interesting due to its unique genetic makeup and potential applications in biotechnology and medicine. One of the most notable characteristics of C. kalidii is its ability to produce unique secondary metabolites. These compounds have shown promise in preliminary studies for their antimicrobial properties, which could be valuable in the development of new antibiotics. Additionally, C. kalidii has been found to possess distinct enzymatic activities that are not commonly observed in other members of the Corynebacterium genus. These enzymes could be harnessed for various industrial applications, including biocatalysis and the synthesis of complex organic molecules. From a research perspective, C. kalidii offers a fascinating model for studying microbial evolution and adaptation. Its genome reveals several unique gene clusters that may provide insights into how bacteria evolve new functions and survive in diverse environments. Overall, Corynebacterium kalidii stands out as a microorganism with significant potential for scientific discovery and practical applications, making it a valuable subject for ongoing and future research.

Corynebacterium kalidii is a fascinating species within the genus Corynebacterium, known for its unique metabolic capabilities and ecological significance. This organism is particularly interesting due to its ability to degrade a variety of complex organic compounds, which positions it as a potential candidate for bioremediation applications. Its enzymatic pathways allow it to break down pollutants, making it valuable in environmental microbiology. One of the standout features of Corynebacterium kalidii is its role in the nitrogen cycle. It has been observed to participate in nitrogen fixation, which is crucial for soil health and fertility. This ability to convert atmospheric nitrogen into a form usable by plants underscores its importance in agricultural microbiology. The potential for enhancing crop yields through the application of this microorganism is a significant area of research. Additionally, Corynebacterium kalidii has garnered attention for its unique phylogenetic position within the Corynebacterium genus. Its genetic makeup and metabolic pathways are subjects of ongoing studies, providing insights into evolutionary adaptations among soil-dwelling bacteria. Understanding these adaptations can lead to advancements in microbial ecology and evolutionary biology. In summary, Corynebacterium kalidii stands out not only for its ecological roles but also for its potential applications in biotechnology and agriculture, making it a valuable organism for further research and exploration.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Mycobacteriales

Family: Corynebacteriaceae

Genus: Corynebacterium

Species: Corynebacterium kalidii

NCBI ID

2931982

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/022/869/005/GCA_022869005.1_ASM2286900v1

File for sequence-based predictions:
GCA_022869005.1_ASM2286900v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Corynebacterium kalidii is a member of the genus Corynebacterium, which includes several species known for their clinical significance. While Corynebacterium kalidii itself is not as widely studied as some of its relatives, it is important to consider its potential implications in human health. Corynebacterium species are often associated with opportunistic infections, particularly in immunocompromised individuals. This organism may contribute to skin infections, respiratory infections, and other localized infections, especially in patients with underlying health conditions. One of the notable aspects of Corynebacterium kalidii is its potential for antimicrobial resistance. Like many bacteria in the Corynebacterium genus, it may exhibit resistance to common antibiotics, which complicates treatment options. This resistance can be attributed to various mechanisms, including the production of beta-lactamases and alterations in target sites, making it crucial for clinicians to consider susceptibility testing when treating infections caused by this organism. In terms of immune evasion strategies, Corynebacterium kalidii may utilize various tactics to avoid detection and destruction by the host's immune system, such as the production of biofilms and the modulation of inflammatory responses. These strategies can enhance its survival in hostile environments, leading to persistent infections. While there is limited documentation on specific outbreaks directly linked to Corynebacterium kalidii, its presence in clinical specimens suggests that it may play a role in polymicrobial infections, where it could act synergistically with other pathogens. Further research is needed to fully elucidate its clinical relevance and potential applications in medical microbiology, including any roles it may have in probiotics or other therapeutic contexts.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Corynebacterium kalidii is a species of bacteria that is primarily associated with soil environments and plant-associated habitats. This microorganism thrives in nutrient-rich soils, often found in agricultural settings where it plays a significant role in the nitrogen cycle. Its ability to fix nitrogen makes it an important contributor to soil fertility, enhancing the growth of various plants by providing essential nutrients. In addition to its role in soil health, Corynebacterium kalidii is also known to inhabit the rhizosphere, the region of soil that is directly influenced by root secretions and associated soil microorganisms. Here, it engages in symbiotic relationships with plant roots, promoting plant growth and health through the enhancement of nutrient uptake. This interaction is particularly beneficial in agricultural ecosystems, where the presence of such bacteria can lead to improved crop yields. Furthermore, Corynebacterium kalidii exhibits remarkable environmental adaptability, allowing it to thrive in various soil types, including sandy and clay-rich soils. Its resilience to different pH levels and moisture conditions enables it to colonize diverse habitats, making it a versatile organism in terrestrial ecosystems. Overall, Corynebacterium kalidii plays a crucial role in maintaining soil health and supporting plant life, highlighting its importance in both natural and managed ecosystems.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Corynebacterium kalidii has shown significant potential in various industrial applications. One of the primary areas of interest is in biotechnology, where Corynebacterium kalidii is utilized for its ability to produce valuable metabolites through fermentation. This process can lead to the production of amino acids, vitamins, and other bioactive compounds that are essential in food and feed industries. In the realm of waste management, Corynebacterium kalidii has demonstrated capabilities in biodegradation, particularly in the breakdown of complex organic materials. This property can be harnessed for the treatment of wastewater and the remediation of contaminated environments, making it a valuable organism in environmental biotechnology. Furthermore, the organism's enzymatic activity is noteworthy, as it can produce specific enzymes that are useful in various pharmaceutical development processes. These enzymes can facilitate the synthesis of pharmaceutical compounds, enhancing the efficiency and yield of drug production. Additionally, there is potential for Corynebacterium kalidii in biofuel production, where its metabolic pathways can be exploited to convert biomass into biofuels through fermentation processes. This application aligns with the growing demand for sustainable energy sources and the reduction of carbon footprints. Overall, Corynebacterium kalidii presents a multifaceted opportunity across several industries, particularly in biotechnology, waste management, pharmaceuticals, and biofuels, showcasing its versatility and importance in modern industrial applications.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	google/gemini-flash-1.5	meta-llama/llama-3-70b-instruct:nitro	google/gemini-pro	anthropic/claude-3.5-sonnet	meta-llama/llama-3-8b-instruct:nitro	google/palm-2-chat-bison-32k	anthropic/claude-3-haiku:beta	openchat/openchat-7b	mistralai/mixtral-8x7b-instruct:nitro	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	google/gemma-7b-it	google/gemma-7b-it	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	openai/gpt-4	openai/gpt-4	perplexity/llama-3-sonar-small-32k-chat	perplexity/llama-3-sonar-small-32k-chat	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	mistralai/mistral-7b-instruct	mistralai/mistral-7b-instruct
Motility	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain variable ✗	N/A	gram stain variable ✗
Aerophilicity	aerobic	N/A	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	facultatively anaerobic ✗	facultatively anaerobic ✗	N/A	N/A	aerobic ✓	aerobic ✓	N/A	N/A	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Biofilm formation	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	N/A	true	false	true	false	false	true	false	true	false	false	false	true	true	false	false	false	false	true	true	false	false	false	false	false	false	false	false
Biosafety level	biosafety level 1	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	true	true	true	false	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true	false	false	true	true
Host association	TRUE	true ✓	true ✓	true ✓	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	N/A	beta	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	gamma	gamma	N/A	N/A	alpha	alpha	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	bacillus ✓	bacillus ✓	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	coccus ✗	coccus ✗	coccus ✗	coccus ✗

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