Burkholderia orbicola

General Information

Burkholderia orbicola is a fascinating microorganism belonging to the genus Burkholderia, which is known for its diverse metabolic capabilities and ecological versatility. One of the most intriguing aspects of B. orbicola is its potential role in plant-microbe interactions. Members of the Burkholderia genus are often found in soil and rhizosphere environments, where they can engage in beneficial relationships with plants, such as promoting plant growth or providing protection against pathogens. Another noteworthy characteristic of B. orbicola is its ability to degrade a wide range of organic compounds. This metabolic flexibility makes it a valuable candidate for bioremediation efforts, where it can be employed to clean up contaminated environments by breaking down pollutants. From a research perspective, B. orbicola is also of interest due to its potential for producing novel bioactive compounds. The genus Burkholderia is known for its production of secondary metabolites with antimicrobial, antifungal, and anticancer properties. Studying B. orbicola could lead to the discovery of new compounds with significant pharmaceutical applications. In summary, Burkholderia orbicola stands out due to its ecological versatility, metabolic diversity, and potential for biotechnological applications. Its interactions with plants, ability to degrade pollutants, and capacity to produce bioactive compounds make it a valuable subject for ongoing and future research.

Burkholderia orbicola is a fascinating bacterium that has garnered attention due to its unique ecological niche and potential applications in biotechnology. This species is primarily isolated from soil and plant environments, indicating its role in the rhizosphere and its interactions with plant roots. What makes B. orbicola particularly interesting is its ability to thrive in diverse environmental conditions, showcasing a remarkable adaptability that is valuable for studies on microbial ecology and plant-microbe interactions. One of the standout features of B. orbicola is its potential for biocontrol. Research has indicated that this organism may possess antifungal properties, making it a candidate for use in sustainable agriculture to combat plant pathogens. This characteristic not only highlights its ecological importance but also positions it as a valuable tool in the development of environmentally friendly pest management strategies. Additionally, B. orbicola is part of the larger Burkholderia genus, which is known for its metabolic versatility. This versatility allows B. orbicola to degrade a variety of organic compounds, which can be harnessed for bioremediation efforts. The ability to break down pollutants makes it a subject of interest for researchers focused on environmental cleanup and sustainability. In summary, Burkholderia orbicola stands out due to its ecological significance, potential for biocontrol, and capabilities in bioremediation, making it a valuable organism for ongoing research in microbiology and environmental science.

Taxonomy

Superkingdom: Bacteria

Phylum: Pseudomonadota

Class: Betaproteobacteria

Order: Burkholderiales

Family: Burkholderiaceae

Genus: Burkholderia

Species: Burkholderia orbicola

NCBI ID

2978683

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/016/595/145/GCA_016595145.1_ASM1659514v1

File for sequence-based predictions:
GCA_016595145.1_ASM1659514v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Burkholderia orbicola is a member of the Burkholderia genus, which is known for its diverse ecological roles and clinical significance. While B. orbicola is less studied compared to other species in the genus, it has been associated with opportunistic infections in immunocompromised patients. Its relevance in human health is underscored by its potential to cause infections in individuals with underlying health conditions, particularly those with cystic fibrosis or chronic granulomatous disease. One of the notable clinical implications of B. orbicola is its antimicrobial resistance. Like many Burkholderia species, it may exhibit resistance to multiple classes of antibiotics, complicating treatment options for infections. This resistance is often attributed to the organism's ability to produce beta-lactamases and other enzymes that degrade antibiotics, as well as its capacity to form biofilms, which protect it from both the host immune response and antimicrobial agents. In terms of immune evasion, B. orbicola may employ various strategies to avoid detection and destruction by the host's immune system, including the modulation of inflammatory responses and the ability to survive within phagocytic cells. This characteristic is particularly concerning in clinical settings, as it can lead to chronic infections that are difficult to eradicate. While there are no widely recognized medical applications of B. orbicola as a probiotic or therapeutic agent, its close relatives in the Burkholderia genus, such as Burkholderia cepacia, are sometimes studied for their potential benefits in bioremediation and plant growth promotion. However, the pathogenic potential of B. orbicola necessitates caution in its handling and study, particularly in clinical microbiology. Overall, the clinical relevance of Burkholderia orbicola lies in its role as an opportunistic pathogen, its mechanisms of antimicrobial resistance, and its potential to cause serious infections in vulnerable populations.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Burkholderia orbicola is a versatile bacterium commonly associated with various soil environments and plant-associated habitats. This microorganism thrives particularly in nutrient-rich soils, where it plays a crucial role in the cycling of nutrients and organic matter. Its presence is often linked to the rhizosphere of plants, where it engages in symbiotic relationships that can enhance plant growth and health by promoting nutrient uptake and providing protection against pathogens. In addition to its role in agricultural ecosystems, Burkholderia orbicola is also found in wetlands and mangrove ecosystems, where it contributes to the degradation of organic materials and the cycling of carbon. This bacterium exhibits remarkable adaptability to varying environmental conditions, including salinity and moisture levels, which allows it to thrive in diverse habitats. Furthermore, Burkholderia orbicola is known for its bioremediation potential, particularly in environments contaminated with pollutants. Its metabolic capabilities enable it to degrade a range of organic compounds, making it a valuable organism in efforts to restore polluted ecosystems. Overall, Burkholderia orbicola is an important player in its associated biomes, contributing to soil health, plant productivity, and environmental sustainability.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Burkholderia orbicola has shown significant potential in various industrial applications. One of the primary areas of interest is in biotechnology, where Burkholderia orbicola is utilized for its ability to produce specific enzymes that can be harnessed in biocatalysis processes. These enzymes can facilitate chemical reactions in a more environmentally friendly manner compared to traditional chemical methods. In the realm of waste management, Burkholderia orbicola has demonstrated capabilities in biodegradation, particularly in the breakdown of complex organic compounds and pollutants. This makes it a valuable organism for the treatment of contaminated environments, such as soil and water, where it can help in the remediation of hazardous waste. Furthermore, the organism has potential applications in biofuel production. Through fermentation processes, Burkholderia orbicola can convert biomass into biofuels, contributing to sustainable energy solutions. Its metabolic pathways are being studied to optimize the yield of biofuels from various feedstocks. In pharmaceutical development, Burkholderia orbicola is being explored for its ability to produce bioactive compounds that may have therapeutic properties. This includes the production of antibiotics and other medicinal compounds, which can be crucial in the fight against antibiotic-resistant bacteria. Overall, Burkholderia orbicola represents a versatile microorganism with promising applications across multiple industries, particularly in enzyme production, biodegradation, and fermentation processes.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 10

LLM predicted phenotypes: 3

Phenotype	High-quality annotation	anthropic/claude-3-haiku:beta	google/gemini-flash-1.5	google/gemini-pro-1.5	anthropic/claude-3.5-sonnet	mistralai/mistral-7b-instruct	google/gemini-pro	google/gemma-7b-it	openchat/openchat-7b	meta-llama/llama-3-70b-instruct:nitro	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mixtral-8x7b-instruct:nitro	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	perplexity/llama-3-sonar-small-32k-chat	perplexity/llama-3-sonar-small-32k-chat	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	openai/gpt-4	openai/gpt-4	openai/gpt-4o	openai/gpt-4o	meta-llama/llama-3-8b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125
Motility	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Gram staining	gram stain negative	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓
Aerophilicity	aerobic	N/A	N/A	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	facultatively anaerobic ✗	facultatively anaerobic ✗	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	true ✗	false ✓	false ✓	true ✗	false ✓	true ✗	false ✓	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓
Biofilm formation	N/A	true	true	true	true	true	true	true	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	N/A	true	true	false	false	false	false	true	false	false	false	false	true	true	true	true	false	false	false	false	true	true	true	true	false	false	false	false
Biosafety level	biosafety level 2	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗
Health association	N/A	true	true	true	true	false	true	true	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false	false	false
Host association	TRUE	true ✓	true ✓	false ✗	false ✗	true ✓	false ✗	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗
Plant pathogenicity	FALSE	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓
Hemolysis	gamma	beta ✗	gamma ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	spirillum ✗	spirillum ✗	bacillus ✓	bacillus ✓

Back to Search