Kluyvera cryocrescens

General Information

Kluyvera cryocrescens is a fascinating microorganism belonging to the family Enterobacteriaceae. This bacterium is particularly interesting due to its psychrotolerant nature, meaning it can thrive in cold environments, which makes it a subject of study for understanding microbial life in low-temperature habitats. One of the unique aspects of K. cryocrescens is its ability to produce a variety of enzymes that are active at low temperatures. These enzymes have potential applications in biotechnology, especially in processes that require biocatalysis at lower temperatures to save energy and reduce costs. For instance, cold-active proteases and lipases from K. cryocrescens are being explored for use in the detergent industry, where they can help in cleaning at lower temperatures, thus conserving energy. Additionally, K. cryocrescens has been studied for its role in the environment, particularly in the degradation of pollutants. Its metabolic versatility allows it to participate in the breakdown of complex organic compounds, making it valuable for bioremediation efforts in cold regions. From a clinical perspective, while K. cryocrescens is not typically associated with human disease, it has occasionally been isolated from clinical specimens. This raises interesting questions about its potential pathogenicity and the conditions under which it might become opportunistic. Overall, Kluyvera cryocrescens is a microorganism of significant interest due to its cold-adaptive enzymes, potential biotechnological applications, and environmental roles. Its study not only enhances our understanding of microbial life in extreme conditions but also opens up new avenues for industrial and environmental applications.

Kluyvera cryocrescens is a fascinating bacterium that has garnered attention due to its unique ecological niche and metabolic capabilities. This organism is notable for its ability to thrive in cold environments, which is reflected in its name, where 'cryo' signifies cold. It was first isolated from a cold environment, highlighting its adaptation to low-temperature habitats, which makes it an interesting subject for studies on psychrophilic microorganisms. One of the most intriguing aspects of K. cryocrescens is its potential for biotechnological applications. The enzymes produced by this bacterium are often adapted to function optimally at lower temperatures, which can be advantageous in various industrial processes, such as bioremediation and the production of biofuels. The cold-active enzymes may also have applications in food processing and preservation, where lower temperatures are typically employed. Furthermore, K. cryocrescens has been studied for its metabolic versatility, particularly its ability to utilize a range of carbon sources. This characteristic not only makes it a valuable organism for understanding microbial metabolism in extreme environments but also positions it as a potential candidate for bioconversion processes. In addition to its ecological and industrial significance, K. cryocrescens contributes to our understanding of microbial diversity and adaptation. Its presence in cold ecosystems can provide insights into the microbial community dynamics and the role of bacteria in nutrient cycling in such environments. Overall, Kluyvera cryocrescens stands out as a unique organism with promising implications for both environmental science and biotechnology.

Taxonomy

Superkingdom: Bacteria

Phylum: Pseudomonadota

Class: Gammaproteobacteria

Order: Enterobacterales

Family: Enterobacteriaceae

Genus: Kluyvera

Species: Kluyvera cryocrescens

NCBI ID

580

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/032/173/255/GCA_032173255.1_ASM3217325v1

File for sequence-based predictions:
GCA_032173255.1_ASM3217325v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Kluyvera cryocrescens is a Gram-negative bacterium that has been increasingly recognized in clinical microbiology. It is primarily associated with infections in immunocompromised patients, particularly those with underlying conditions such as diabetes or malignancies. Clinical implications of K. cryocrescens include its potential role in causing bacteremia, urinary tract infections, and wound infections. The organism is notable for its ability to survive in various environments, which may contribute to its pathogenicity in hospital settings. One of the significant concerns regarding Kluyvera cryocrescens is its antimicrobial resistance. Reports indicate that this bacterium can exhibit resistance to multiple classes of antibiotics, including beta-lactams and aminoglycosides, complicating treatment options for infected patients. The mechanisms of resistance may involve the production of beta-lactamases and alterations in membrane permeability, which allow the organism to evade the effects of commonly used antibiotics. In terms of immune evasion, K. cryocrescens may employ strategies such as biofilm formation, which protects it from both the host immune response and antibiotic treatment. This characteristic is particularly concerning in the context of nosocomial infections, where biofilms can form on medical devices and lead to persistent infections. While Kluyvera cryocrescens is not commonly associated with outbreaks, its presence in clinical specimens highlights the need for vigilance in monitoring and identifying this organism in healthcare settings. Understanding its clinical relevance is crucial for developing effective treatment protocols and infection control measures.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Kluyvera cryocrescens is a bacterium that is primarily associated with cold environments and has been isolated from various psychrophilic habitats. This microorganism thrives in polar regions and deep-sea environments, where temperatures are consistently low. Its ability to grow at low temperatures makes it an important player in these unique ecosystems, contributing to the overall microbial diversity and functioning of these biomes. In the polar regions, Kluyvera cryocrescens can be found in sea ice and glacial meltwater, where it plays a role in nutrient cycling and organic matter decomposition. The presence of this bacterium in such extreme conditions highlights its adaptation mechanisms, including the production of cold-active enzymes that facilitate metabolic processes at low temperatures. Additionally, Kluyvera cryocrescens has been identified in marine sediments, where it interacts with other microbial communities. This interaction can lead to symbiotic relationships that enhance nutrient availability and promote the growth of other organisms in the ecosystem. Its role in biogeochemical cycles, particularly in the degradation of organic compounds, underscores its ecological significance. Overall, Kluyvera cryocrescens exemplifies the adaptability of microorganisms to extreme environments and their essential contributions to the health and stability of cold biomes.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Kluyvera cryocrescens has shown potential in various industrial applications, particularly in the fields of biotechnology, waste management, and pharmaceutical development. This organism is known for its ability to thrive in cold environments, which makes it a candidate for processes that require low-temperature conditions. In biotechnology, Kluyvera cryocrescens can be utilized in fermentation processes to produce valuable metabolites. Its unique metabolic pathways allow for the conversion of substrates into useful products, which can be harnessed in the production of organic acids and other biochemicals. In the realm of waste management, this microorganism has demonstrated capabilities in biodegradation of various pollutants. Its enzymatic activity can break down complex organic compounds, making it useful in the treatment of wastewater and the remediation of contaminated sites. This is particularly important in addressing environmental challenges associated with industrial waste. Furthermore, Kluyvera cryocrescens has potential applications in biofuel production. Its metabolic processes can be optimized to enhance the yield of biofuels from biomass, contributing to sustainable energy solutions. The organism's ability to ferment sugars into ethanol or other biofuels under low-temperature conditions can be particularly advantageous in regions where traditional fermentation processes are less efficient. In pharmaceutical development, the unique biochemical properties of Kluyvera cryocrescens may lead to the discovery of novel compounds with therapeutic potential. Its ability to produce specific enzymes can be explored for the development of pharmaceuticals, including antibiotics and other bioactive molecules. Overall, Kluyvera cryocrescens represents a versatile microorganism with significant potential across multiple industries, particularly in processes that benefit from its cold-adapted characteristics.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 10

LLM predicted phenotypes: 3

Phenotype	High-quality annotation	anthropic/claude-3.5-sonnet	openai/gpt-4	openai/gpt-4	mistralai/mixtral-8x7b-instruct:nitro	meta-llama/llama-3-70b-instruct:nitro	anthropic/claude-3-haiku:beta	meta-llama/llama-3-8b-instruct:nitro	openchat/openchat-7b	google/gemma-7b-it	google/gemini-flash-1.5	google/gemini-flash-1.5	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	google/gemini-pro-1.5	google/gemini-pro-1.5	perplexity/llama-3-sonar-small-32k-chat	perplexity/llama-3-sonar-small-32k-chat	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	openai/gpt-4o	openai/gpt-4o	mistralai/mistral-7b-instruct	mistralai/mistral-7b-instruct	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	google/gemini-pro	google/gemini-pro	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b
Motility	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓
Gram staining	gram stain negative	gram stain negative ✓	N/A	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓
Aerophilicity	aerobic	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	N/A	N/A	N/A	N/A	N/A	N/A	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Biofilm formation	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	TRUE	true ✓	true ✓	true ✓	false ✗	true ✓	true ✓	false ✗	false ✗	true ✓	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓
Biosafety level	biosafety level 2	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓
Health association	N/A	true	true	true	true	true	true	true	false	true	true	true	false	false	true	true	true	true	false	false	true	true	false	false	false	false	true	true	true	true
Host association	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Plant pathogenicity	TRUE	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	N/A	gamma	beta	beta	N/A	N/A	N/A	N/A	N/A	N/A	gamma	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓

Back to Search