Lelliottia amnigena

General Information

Lelliottia amnigena is a fascinating microorganism that belongs to the family Enterobacteriaceae. This bacterium is particularly interesting due to its versatility in various environments and its potential implications in both environmental and clinical settings. Originally isolated from water sources, L. amnigena has demonstrated a remarkable ability to adapt to different ecological niches, which makes it a subject of interest for studies on microbial ecology and environmental microbiology. One of the unique aspects of Lelliottia amnigena is its metabolic diversity. It can utilize a wide range of substrates for growth, which underscores its adaptability and potential for biotechnological applications. Researchers are exploring its capabilities in bioremediation, particularly in the degradation of pollutants and waste materials, making it a valuable organism for environmental cleanup efforts. In the clinical context, L. amnigena has been identified as an opportunistic pathogen. While it is not commonly associated with human disease, it has been isolated from various clinical specimens, including blood and urine. This highlights the importance of understanding its pathogenic potential and mechanisms of infection, which could provide insights into preventing and managing infections caused by this bacterium. Moreover, Lelliottia amnigena is of interest due to its antibiotic resistance profiles. Studies have shown that it possesses resistance to multiple antibiotics, which poses challenges for treatment and underscores the need for ongoing surveillance and research into effective antimicrobial strategies. Overall, Lelliottia amnigena is a microorganism that offers valuable insights into microbial ecology, environmental biotechnology, and clinical microbiology. Its adaptability, metabolic versatility, and potential pathogenicity make it a significant subject for scientific research and practical applications.

Lelliottia amnigena is a fascinating bacterium that belongs to the family Enterobacteriaceae. This organism is particularly interesting due to its ability to thrive in aquatic environments, which sets it apart from many of its relatives that are primarily associated with terrestrial habitats. It was first isolated from a freshwater source, highlighting its ecological niche and adaptability to varying environmental conditions. One of the unique aspects of Lelliottia amnigena is its potential role in bioremediation. Given its aquatic origins, this bacterium may possess metabolic pathways that allow it to degrade pollutants in water, making it a candidate for studies focused on environmental cleanup and sustainability. Researchers are particularly interested in understanding the enzymatic processes involved in its metabolism, which could lead to innovative applications in waste management. Additionally, Lelliottia amnigena has been noted for its antimicrobial resistance patterns, which are crucial for understanding the dynamics of resistance in environmental bacteria. This characteristic makes it a valuable organism for studying the mechanisms of resistance and the transfer of resistance genes in microbial communities. Furthermore, the genomic analysis of Lelliottia amnigena has revealed insights into its evolutionary adaptations, providing a window into the genetic diversity within the Enterobacteriaceae family. This can enhance our understanding of microbial evolution and the ecological roles these bacteria play in their respective environments. In summary, Lelliottia amnigena stands out due to its aquatic lifestyle, potential for bioremediation, and significance in the study of antimicrobial resistance and microbial evolution. Its unique characteristics make it a valuable subject for ongoing research in microbiology and environmental science.

Taxonomy

Superkingdom: Bacteria

Phylum: Pseudomonadota

Class: Gammaproteobacteria

Order: Enterobacterales

Family: Enterobacteriaceae

Genus: Lelliottia

Species: Lelliottia amnigena

NCBI ID

61646

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/019/047/465/GCA_019047465.1_ASM1904746v1

File for sequence-based predictions:
GCA_019047465.1_ASM1904746v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The bacterium Lelliottia amnigena is a member of the Enterobacteriaceae family and has been associated with various clinical implications, particularly in immunocompromised patients. It is known to cause infections such as bacteremia and pneumonia, especially in individuals with underlying health conditions. The organism has been isolated from clinical specimens, including blood and respiratory samples, indicating its potential pathogenicity in hospital settings. One of the significant concerns regarding Lelliottia amnigena is its antimicrobial resistance. It has shown resistance to multiple classes of antibiotics, which complicates treatment options for infections caused by this organism. The mechanisms of resistance may involve the production of beta-lactamases and other enzymes that degrade antibiotics, making it a challenge for healthcare providers to manage infections effectively. In terms of immune evasion, Lelliottia amnigena may employ strategies such as altering surface antigens and producing virulence factors that help it survive in the host environment. This ability to evade the immune response contributes to its pathogenic potential, particularly in patients with weakened immune systems. While Lelliottia amnigena is not commonly recognized as a major pathogen, its role in nosocomial infections and its association with serious clinical outcomes highlight the need for ongoing surveillance and research. Understanding its epidemiology and resistance patterns is crucial for developing effective treatment protocols and improving patient outcomes.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Lelliottia amnigena is a bacterium primarily associated with freshwater environments, particularly in areas where organic matter is abundant. This microorganism thrives in aquatic habitats such as rivers, lakes, and wetlands, where it plays a crucial role in the decomposition of organic materials. Its presence is often linked to the breakdown of complex organic compounds, contributing to nutrient cycling within these ecosystems. In these freshwater biomes, Lelliottia amnigena interacts with various other microorganisms, forming a part of the microbial community that supports the overall health of the ecosystem. It can engage in symbiotic relationships with other bacteria, enhancing the degradation of pollutants and organic waste, which is vital for maintaining water quality. Additionally, this bacterium exhibits remarkable environmental adaptability, allowing it to thrive in varying conditions, such as changes in temperature and nutrient availability. Its ability to metabolize diverse substrates makes it a key player in the biodegradation processes that occur in these habitats, thus contributing to the ecological balance and sustainability of freshwater ecosystems. Overall, Lelliottia amnigena is an important microorganism within its biome, influencing both the chemical and biological dynamics of its environment.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Lelliottia amnigena has shown potential in various industrial applications, particularly in the fields of biotechnology, waste management, and pharmaceutical development. This organism is known for its ability to participate in biodegradation, making it valuable in the treatment of contaminated environments. For instance, Lelliottia amnigena can break down complex organic compounds, which is crucial in waste treatment processes, helping to reduce pollution and improve waste management practices. In the realm of biotechnology, Lelliottia amnigena has been studied for its enzymatic activities, which can be harnessed for the production of various bioproducts. The organism's enzymes may facilitate fermentation processes, leading to the production of biofuels or other valuable metabolites. This capability positions Lelliottia amnigena as a potential candidate for biofuel production, where it could contribute to the development of sustainable energy sources. Moreover, the pharmaceutical industry may benefit from the unique metabolic pathways of Lelliottia amnigena, which could lead to the discovery of novel compounds with therapeutic properties. The organism's ability to produce specific metabolites through fermentation could be explored for the synthesis of antibiotics or other pharmaceuticals, highlighting its significance in pharmaceutical development. Overall, Lelliottia amnigena presents a promising avenue for innovation across multiple industries, particularly through its roles in biodegradation, fermentation, and enzyme production.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	anthropic/claude-3.5-sonnet	anthropic/claude-3.5-sonnet	google/gemini-flash-1.5	mistralai/mixtral-8x7b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	google/palm-2-chat-bison-32k	mistralai/mistral-7b-instruct	openchat/openchat-7b	google/gemini-pro	meta-llama/llama-3-70b-instruct:nitro	anthropic/claude-3-haiku:beta	anthropic/claude-3-haiku:beta	openai/gpt-4	openai/gpt-4	openai/gpt-4o	openai/gpt-4o	meta-llama/llama-3-8b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	google/gemini-pro-1.5	google/gemini-pro-1.5	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	google/gemma-7b-it	google/gemma-7b-it	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b
Motility	TRUE	true ✓	true ✓	true ✓	false ✗	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓
Gram staining	gram stain negative	N/A	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain positive ✗	gram stain positive ✗	gram stain negative ✓	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓
Aerophilicity	aerobic	facultatively anaerobic ✗	facultatively anaerobic ✗	N/A	facultatively anaerobic ✗	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	aerotolerant ✗	aerotolerant ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Biofilm formation	N/A	true	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false	true	true	true	true
Animal pathogenicity	TRUE	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	false ✗	true ✓	false ✗	true ✓	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓
Biosafety level	biosafety level 2	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓
Health association	N/A	true	true	true	true	true	true	false	true	true	true	true	true	true	true	true	true	false	false	false	false	true	true	false	false	true	true	true	true
Host association	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	true ✓	true ✓	false ✗	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓
Plant pathogenicity	N/A	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	true	true	false	false	false	false	false	false
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	N/A	gamma	gamma	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	alpha	alpha	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓

Back to Search