Enterobacter cancerogenus

General Information

Enterobacter cancerogenus is a fascinating microorganism within the Enterobacter genus, known for its unique and diverse metabolic capabilities. One of the most intriguing aspects of E. cancerogenus is its potential role in human health, particularly its association with opportunistic infections. This species has been isolated from various clinical specimens, including wounds, blood, and respiratory tract infections, highlighting its clinical significance. E. cancerogenus is also notable for its antibiotic resistance profiles, which make it a subject of interest in the study of antimicrobial resistance mechanisms. The ability of this bacterium to resist multiple antibiotics poses challenges for treatment and underscores the importance of ongoing research to develop effective therapeutic strategies. From an ecological perspective, E. cancerogenus can be found in diverse environments, including soil and water, which suggests its adaptability and resilience. This environmental versatility is linked to its metabolic diversity, allowing it to utilize a wide range of substrates for growth. In the realm of biotechnology, E. cancerogenus has shown potential in bioremediation processes. Its ability to degrade various pollutants makes it a valuable candidate for cleaning up contaminated environments. This capability is particularly relevant in the context of industrial waste management and environmental conservation efforts. Overall, Enterobacter cancerogenus stands out due to its clinical relevance, antibiotic resistance, metabolic versatility, and biotechnological potential. These characteristics make it a significant organism for both medical research and environmental applications.

Enterobacter cancerogenus is a fascinating bacterium that has garnered attention due to its unique ecological niche and potential implications in health and disease. This species is part of the Enterobacter genus, which is known for its diverse metabolic capabilities and adaptability to various environments, including soil, water, and the gastrointestinal tracts of animals and humans. One of the most interesting aspects of E. cancerogenus is its association with cancer. Research has indicated that certain strains of this bacterium may be linked to the development of cancer in specific contexts, particularly in immunocompromised individuals. This connection opens up avenues for further investigation into the role of gut microbiota in cancer pathogenesis, making E. cancerogenus a valuable organism for studies in microbiome research and oncology. Additionally, E. cancerogenus exhibits remarkable metabolic versatility, allowing it to utilize a wide range of substrates for growth. This characteristic not only contributes to its survival in diverse environments but also makes it a potential candidate for biotechnological applications, such as bioremediation or the production of biofuels. Furthermore, the ability of E. cancerogenus to produce various enzymes, including those involved in the degradation of complex organic compounds, highlights its potential utility in industrial processes. The exploration of these enzymatic pathways could lead to the development of novel biocatalysts for environmental and industrial applications. In summary, Enterobacter cancerogenus stands out due to its intriguing links to cancer, its metabolic flexibility, and its potential applications in biotechnology. Continued research on this organism could yield significant insights into both microbial ecology and human health.

Taxonomy

Superkingdom: Bacteria

Phylum: Pseudomonadota

Class: Gammaproteobacteria

Order: Enterobacterales

Family: Enterobacteriaceae

Genus: Enterobacter

Species: Enterobacter cancerogenus

NCBI ID

69218

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/019/047/785/GCA_019047785.1_ASM1904778v1

File for sequence-based predictions:
GCA_019047785.1_ASM1904778v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Enterobacter cancerogenus is a member of the Enterobacter genus, which is known for its clinical significance in human health. It has been associated with various infections, particularly in immunocompromised patients. Urinary tract infections (UTIs) and nosocomial infections are common clinical manifestations linked to this organism. Its pathogenicity is attributed to its ability to produce beta-lactamases, which confer antimicrobial resistance against a range of antibiotics, complicating treatment options. This resistance is particularly concerning in hospital settings where multidrug-resistant strains can emerge, leading to increased morbidity and healthcare costs. In terms of immune evasion, Enterobacter cancerogenus can alter its surface structures and produce virulence factors that help it evade detection and destruction by the host's immune system. This ability to persist in the human body can lead to chronic infections, especially in patients with underlying health conditions. While Enterobacter cancerogenus is primarily recognized for its role in pathogenicity, there is ongoing research into its potential applications in biotechnology and medicine. Some strains of Enterobacter species are being explored for their use in bioremediation and as potential probiotics, although the clinical relevance of Enterobacter cancerogenus in these areas remains to be fully established. Overall, the clinical implications of Enterobacter cancerogenus underscore the importance of monitoring and managing infections caused by this organism, particularly in vulnerable populations.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Enterobacter cancerogenus is primarily associated with a variety of human-associated environments, particularly within the gastrointestinal tract of mammals, including humans. This microorganism thrives in the intestinal microbiome, where it plays a significant role in the digestion of complex carbohydrates and the synthesis of essential vitamins. Its presence is often indicative of a balanced gut flora, although it can also be associated with opportunistic infections when the host's immune system is compromised. In addition to its role in the gut, Enterobacter cancerogenus can be found in soil and water environments, where it contributes to the nutrient cycling process. It is known to participate in the breakdown of organic matter, thus enhancing soil fertility and promoting plant growth. This bacterium can also be involved in symbiotic relationships with certain plants, aiding in nutrient uptake and enhancing plant resilience against pathogens. Notably, Enterobacter cancerogenus exhibits a remarkable ability to adapt to varying environmental conditions, including changes in pH and temperature, which allows it to thrive in diverse habitats. Its metabolic versatility enables it to utilize a wide range of substrates, making it a key player in both natural ecosystems and human-associated environments. Overall, Enterobacter cancerogenus exemplifies the intricate relationships microorganisms have with their environments, highlighting its importance in both ecological balance and human health.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Enterobacter cancerogenus has shown significant potential in various industrial applications. One of the primary areas of interest is in biotechnology, where it is utilized in fermentation processes to produce valuable metabolites. This organism can ferment a range of carbohydrates, making it useful in the production of organic acids, alcohols, and other biochemicals. In the realm of waste management, Enterobacter cancerogenus has been studied for its ability to degrade pollutants, particularly in biodegradation processes. It can break down complex organic compounds, which is beneficial for treating wastewater and reducing environmental contaminants. Additionally, this microorganism has potential applications in biofuel production. Its metabolic pathways can be harnessed to convert biomass into biofuels through fermentation, contributing to sustainable energy solutions. In pharmaceutical development, Enterobacter cancerogenus is of interest due to its ability to produce various enzymes that can be used in drug synthesis and biocatalysis. The enzymatic activity of this organism can facilitate the production of pharmaceuticals in a more environmentally friendly manner. Overall, Enterobacter cancerogenus demonstrates versatility across multiple industries, particularly in fermentation, biodegradation, and enzyme production, making it a valuable organism for future industrial applications.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 11

LLM predicted phenotypes: 2

Phenotype	High-quality annotation	google/gemini-pro-1.5	anthropic/claude-3.5-sonnet	anthropic/claude-3.5-sonnet	openai/gpt-4	openai/gpt-4	google/gemini-flash-1.5	anthropic/claude-3-haiku:beta	meta-llama/llama-3-70b-instruct:nitro	google/gemma-7b-it	mistralai/mixtral-8x7b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	mistralai/mistral-7b-instruct	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	google/gemini-pro	google/gemini-pro	meta-llama/llama-3-8b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	openchat/openchat-7b	openchat/openchat-7b	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b
Motility	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Gram staining	gram stain negative	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain variable ✗	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓
Aerophilicity	aerobic	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	N/A	N/A	facultatively anaerobic ✗	N/A	facultatively anaerobic ✗	N/A	N/A	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	true ✗	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Biofilm formation	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Animal pathogenicity	FALSE	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗
Biosafety level	biosafety level 2	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓
Health association	N/A	true	true	true	true	true	true	true	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Host association	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Plant pathogenicity	TRUE	true ✓	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	N/A	N/A	gamma	gamma	beta	beta	gamma	alpha	N/A	alpha	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	gamma	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓

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