Streptomyces stelliscabiei

General Information

Streptomyces stelliscabiei is a fascinating microorganism belonging to the genus Streptomyces, which is renowned for its prolific production of antibiotics and other secondary metabolites. This particular species is notable for its role in plant pathology, specifically as a causative agent of common scab in potatoes and other root crops. The disease manifests as rough, corky lesions on the surface of the tubers, which can significantly reduce their market value. One of the most intriguing aspects of S. stelliscabiei is its ability to produce a variety of phytotoxins, including thaxtomin A, which is directly involved in the development of scab symptoms. Thaxtomin A disrupts the normal growth of plant cell walls, leading to the characteristic lesions. This toxin is a key factor in the pathogenicity of the organism and has been a subject of extensive research. From a biotechnological perspective, S. stelliscabiei is valuable due to its genetic and metabolic diversity. The species has a large genome that encodes numerous biosynthetic gene clusters, which are responsible for the production of a wide array of bioactive compounds. These compounds have potential applications in agriculture, medicine, and industry. Moreover, S. stelliscabiei is part of a broader group of Streptomyces species that are studied for their complex life cycle and differentiation processes. Understanding these processes can provide insights into bacterial development and the regulation of secondary metabolism. In summary, Streptomyces stelliscabiei is a microorganism of significant interest due to its role in plant disease, its production of unique phytotoxins, and its potential for biotechnological applications. Its study not only helps in managing agricultural diseases but also opens avenues for discovering new natural products with diverse applications.

Streptomyces stelliscabiei is a fascinating actinobacterium known for its remarkable ability to produce a diverse array of bioactive compounds, including antibiotics and antifungal agents. This organism is part of the larger genus Streptomyces, which is renowned for its significant contributions to natural product chemistry and pharmaceutical development. What makes S. stelliscabiei particularly interesting is its unique metabolic pathways that allow it to synthesize compounds with potential therapeutic applications. One of the standout features of S. stelliscabiei is its ability to thrive in various environmental conditions, which enhances its potential for biotechnological applications. This adaptability is crucial for researchers looking to harness its capabilities for drug discovery and agricultural applications, particularly in the development of natural pesticides and herbicides. Moreover, S. stelliscabiei has been studied for its role in soil health and plant growth promotion, making it a valuable organism in the field of sustainable agriculture. The production of secondary metabolites by this species not only contributes to its ecological niche but also offers insights into the evolutionary adaptations of soil-dwelling microorganisms. In summary, Streptomyces stelliscabiei stands out due to its rich biosynthetic potential, ecological significance, and contributions to both pharmaceutical and agricultural sciences, making it a subject of ongoing research interest.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Kitasatosporales

Family: Streptomycetaceae

Genus: Streptomyces

Species: Streptomyces stelliscabiei

NCBI ID

146820

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCF/001/189/035/GCF_001189035.1_ASM118903v1

File for sequence-based predictions:
GCF_001189035.1_ASM118903v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Streptomyces stelliscabiei is a member of the genus Streptomyces, which is known for its significant role in the production of antibiotics and other bioactive compounds. While S. stelliscabiei itself is not commonly associated with human infections, its relatives have been implicated in various infections and are known for their pathogenic potential in immunocompromised individuals. This organism is primarily recognized for its ability to produce secondary metabolites, which can have therapeutic applications, including the development of new antibiotics. In terms of immune response, S. stelliscabiei may interact with the human microbiome, potentially influencing gut health and the overall immune system through the production of metabolites that can modulate immune functions. However, the specific mechanisms of immune evasion or pathogenicity in humans are not well-documented for this species. Moreover, the genus Streptomyces is known for its antimicrobial resistance mechanisms, which can complicate treatment options for infections caused by related species. Understanding the resistance patterns and metabolic capabilities of S. stelliscabiei could provide insights into its potential use in biotechnological applications, such as the development of probiotics or as a source of novel therapeutic agents. Overall, while Streptomyces stelliscabiei may not be directly linked to specific diseases, its role in antibiotic production and potential interactions with the human microbiome underscore its relevance in the field of microbiology and medicine.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Streptomyces stelliscabiei is a species of actinobacteria commonly found in soil ecosystems and decaying organic matter. This microorganism thrives in environments rich in organic material, where it plays a crucial role in the decomposition process. Its ability to break down complex organic compounds contributes significantly to nutrient cycling within these biomes. Soil Microhabitats: Within the soil, Streptomyces stelliscabiei occupies various microhabitats, often found in association with plant roots. This proximity allows it to engage in mutualistic relationships with plants, aiding in nutrient uptake and enhancing plant growth through the production of growth-promoting substances. Decomposing Organic Matter: In environments characterized by decaying plant material, Streptomyces stelliscabiei is instrumental in the breakdown of cellulose and lignin, contributing to the formation of humus. This process not only enriches the soil but also supports a diverse community of microorganisms, creating a dynamic ecosystem. Symbiotic Interactions: The organism is known to produce a variety of bioactive compounds, including antibiotics, which can inhibit the growth of competing microorganisms. This ability allows Streptomyces stelliscabiei to establish itself in nutrient-rich environments while also influencing the microbial community structure. Overall, Streptomyces stelliscabiei exemplifies the intricate relationships within terrestrial biomes, showcasing its importance in nutrient cycling, plant health, and microbial diversity.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Streptomyces stelliscabiei is known for its significant contributions to various industrial applications, particularly in the fields of biotechnology, pharmaceutical development, and agriculture. This actinobacterium is recognized for its ability to produce a wide range of bioactive compounds, including antibiotics and enzymes, which are crucial in the development of new pharmaceuticals. In the realm of biotechnology, Streptomyces stelliscabiei is involved in the fermentation processes that lead to the production of valuable metabolites. These metabolites can be harnessed for their antimicrobial properties, making them essential in the formulation of new drugs to combat resistant bacterial strains. Moreover, this microorganism plays a role in waste management through its capacity for biodegradation. It can break down complex organic materials, thus aiding in the treatment of waste and the recycling of nutrients in various environments. This capability is particularly useful in composting and bioremediation efforts, where Streptomyces stelliscabiei can help in the degradation of pollutants and the restoration of contaminated sites. In addition to these applications, Streptomyces stelliscabiei is also explored for its potential in biofuel production. The enzymes produced by this organism can facilitate the breakdown of lignocellulosic biomass, making it a candidate for enhancing the efficiency of biofuel production processes. Overall, Streptomyces stelliscabiei exemplifies the versatility of actinobacteria in industrial applications, showcasing its importance in pharmaceutical development, waste management, and biofuel production through various biotechnological processes.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	google/gemini-flash-1.5	google/gemini-pro-1.5	google/gemini-pro	google/palm-2-chat-bison-32k	google/gemma-7b-it	meta-llama/llama-3-8b-instruct:nitro	openchat/openchat-7b	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	openai/gpt-4	openai/gpt-4	anthropic/claude-3.5-sonnet	anthropic/claude-3.5-sonnet	meta-llama/llama-3-70b-instruct:nitro	meta-llama/llama-3-70b-instruct:nitro	openai/gpt-4o	openai/gpt-4o	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	mistralai/mistral-7b-instruct	mistralai/mistral-7b-instruct	anthropic/claude-3-haiku:beta	anthropic/claude-3-haiku:beta	perplexity/llama-3-sonar-small-32k-chat	perplexity/llama-3-sonar-small-32k-chat	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mixtral-8x7b-instruct:nitro
Motility	N/A	false	false	false	false	true	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	true	true	false	false
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain negative ✗	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	aerobic ✓	aerobic ✓	facultatively anaerobic ✗	facultatively anaerobic ✗	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗
Biofilm formation	N/A	true	true	true	true	true	true	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false	true	true	true	true	true	true
Animal pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	false	true	true	true	true	true	false	false	false	false	false	true	true	true	true	true	true	true	true	true	true	false	false	true	true	true	true	true	true
Host association	FALSE	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗
Plant pathogenicity	FALSE	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗
Spore formation	TRUE	true ✓	true ✓	true ✓	true ✓	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Hemolysis	N/A	gamma	N/A	N/A	N/A	alpha	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	tail	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗

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