Burkholderia guangdongensis

General Information

Burkholderia guangdongensis is a fascinating microorganism that belongs to the genus Burkholderia, which is known for its metabolic diversity and ecological versatility. This species was first isolated from a forest soil sample in Guangdong Province, China, which highlights its natural habitat in soil environments. One of the most intriguing aspects of B. guangdongensis is its potential for bioremediation. This organism has shown the ability to degrade various environmental pollutants, making it a valuable candidate for cleaning up contaminated sites. Additionally, Burkholderia guangdongensis is part of a genus that includes both plant-associated and pathogenic species, which makes it an interesting subject for studying plant-microbe interactions and microbial pathogenicity. The metabolic pathways of B. guangdongensis are also of significant interest, as they may reveal novel enzymes and biochemical processes that could be harnessed for industrial applications. Another key characteristic of B. guangdongensis is its potential role in promoting plant growth. Some members of the Burkholderia genus are known to produce plant growth-promoting substances, and B. guangdongensis may possess similar capabilities, which could be beneficial for agricultural practices. In summary, Burkholderia guangdongensis stands out due to its environmental adaptability, potential for bioremediation, and possible applications in agriculture and industry. Its unique characteristics make it a valuable subject for further research and exploration.

Burkholderia guangdongensis is a fascinating bacterium that was first isolated from a patient with pneumonia in Guangdong, China. This organism is part of the Burkholderia genus, which is known for its diverse metabolic capabilities and environmental versatility. One of the most interesting aspects of B. guangdongensis is its potential pathogenicity; it has been associated with various infections, particularly in immunocompromised individuals, making it a subject of interest in clinical microbiology and infectious disease research. This species is notable for its resistance to multiple antibiotics, which poses significant challenges in treatment options for infections. The genetic mechanisms underlying this resistance are a key area of study, as understanding them could lead to better therapeutic strategies and insights into antibiotic resistance in general. Additionally, B. guangdongensis has been shown to possess biodegradative capabilities, particularly in the breakdown of environmental pollutants. This characteristic highlights its potential utility in bioremediation efforts, where it could be employed to clean up contaminated environments, thus contributing to ecological health. Furthermore, the organism's genomic plasticity allows it to adapt to various environments, which is a topic of interest for researchers studying microbial evolution and adaptation. The ability of B. guangdongensis to thrive in diverse ecological niches makes it a valuable model for understanding microbial interactions in both clinical and environmental contexts. In summary, Burkholderia guangdongensis stands out due to its clinical relevance, antibiotic resistance, and bioremediation potential, making it a significant organism for ongoing research in microbiology, environmental science, and public health.

Taxonomy

Superkingdom: Bacteria

Phylum: Pseudomonadota

Class: Betaproteobacteria

Order: Burkholderiales

Family: Burkholderiaceae

Genus: Burkholderia

Species: Burkholderia guangdongensis

NCBI ID

1792500

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/013/403/875/GCA_013403875.1_ASM1340387v1

File for sequence-based predictions:
GCA_013403875.1_ASM1340387v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Burkholderia guangdongensis is a member of the Burkholderia genus, which is known for its diverse ecological roles and clinical significance. This bacterium has been associated with various infections, particularly in immunocompromised patients. It is recognized for its pathogenicity, often leading to severe respiratory infections, especially in individuals with underlying health conditions such as cystic fibrosis or chronic lung diseases. The organism's ability to form biofilms contributes to its virulence and persistence in the human body, complicating treatment efforts. One of the notable clinical implications of Burkholderia guangdongensis is its antimicrobial resistance. This species exhibits resistance to multiple classes of antibiotics, which poses significant challenges in clinical settings. The presence of resistance mechanisms, such as the production of beta-lactamases, underscores the need for careful antibiotic stewardship and the development of alternative therapeutic strategies. In terms of immune evasion, Burkholderia guangdongensis can manipulate host immune responses, allowing it to survive and thrive within the host. This includes the ability to evade phagocytosis and modulate inflammatory responses, which can lead to chronic infections. While research on Burkholderia guangdongensis is still emerging, its role in outbreaks, particularly in healthcare-associated infections, highlights the importance of surveillance and infection control measures. Understanding the clinical implications of this organism is crucial for developing effective treatment protocols and improving patient outcomes.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Burkholderia guangdongensis is a versatile bacterium primarily associated with soil ecosystems and plant rhizospheres. This microorganism thrives in a variety of environments, particularly in regions with high organic matter content, such as decaying plant material and nutrient-rich soils. Its ability to adapt to different soil types allows it to play a significant role in nutrient cycling and soil health. In its natural habitat, Burkholderia guangdongensis engages in symbiotic relationships with various plants, promoting growth and enhancing nutrient uptake. This interaction is particularly beneficial in agricultural settings, where it can help improve crop yields by facilitating the availability of essential nutrients like nitrogen and phosphorus. Additionally, this bacterium is known for its bioremediation potential, as it can degrade a range of organic pollutants, making it valuable in contaminated environments. Its presence in wetlands and mangrove ecosystems further highlights its ecological importance, as it contributes to the overall health and stability of these sensitive habitats. Overall, Burkholderia guangdongensis exemplifies the intricate relationships within terrestrial biomes, showcasing its adaptability and essential roles in maintaining ecological balance.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Burkholderia guangdongensis has shown significant potential in various industrial applications. One of the most notable areas is in biotechnology, where it is utilized for its ability to produce a range of enzymes that can be harnessed in biocatalysis processes. These enzymes are particularly valuable in the food industry for fermentation processes, enhancing flavor and texture in products such as dairy and fermented beverages. In the realm of waste management, Burkholderia guangdongensis has demonstrated capabilities in biodegradation, particularly in the breakdown of complex organic pollutants. This makes it a candidate for use in bioremediation efforts, where it can help in the detoxification of contaminated environments, such as oil spills or heavy metal-laden sites. Furthermore, this microorganism has been explored for its potential in biofuel production. Its metabolic pathways can be optimized to convert biomass into biofuels through fermentation processes, contributing to sustainable energy solutions. In pharmaceutical development, Burkholderia guangdongensis has been studied for its production of bioactive compounds that may have therapeutic properties. This includes the synthesis of antibiotics and other medicinal compounds, showcasing its versatility in the pharmaceutical industry. Overall, Burkholderia guangdongensis represents a promising organism with diverse applications across multiple industries, particularly in enzyme production, biodegradation, and biocatalysis, making it a valuable asset in the pursuit of sustainable industrial practices.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 8

LLM predicted phenotypes: 5

Phenotype	High-quality annotation	google/gemini-flash-1.5	anthropic/claude-3-haiku:beta	mistralai/mixtral-8x7b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	google/palm-2-chat-bison-32k	meta-llama/llama-3-70b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	openchat/openchat-7b	microsoft/phi-3-mini-128k-instruct	google/gemini-pro	google/gemini-pro-1.5	google/gemini-pro-1.5	openai/gpt-4	openai/gpt-4	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	anthropic/claude-3.5-sonnet	anthropic/claude-3.5-sonnet	google/gemma-7b-it	google/gemma-7b-it	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	mistralai/mistral-7b-instruct	mistralai/mistral-7b-instruct
Motility	N/A	true	true	true	true	true	true	true	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Gram staining	gram stain negative	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓
Aerophilicity	aerobic	N/A	N/A	facultatively anaerobic ✗	N/A	N/A	N/A	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	false ✓	true ✗	true ✗	true ✗	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗
Biofilm formation	N/A	true	true	true	true	true	true	true	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	N/A	true	true	false	true	true	true	true	false	true	true	true	true	false	false	true	true	true	true	false	false	true	true	true	true	false	false
Biosafety level	biosafety level 2	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 3 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓
Health association	N/A	true	true	true	true	true	true	true	false	true	true	true	true	false	false	false	false	true	true	true	true	true	true	true	true	false	false
Host association	N/A	true	true	true	true	true	true	true	false	true	true	true	true	false	false	false	false	true	true	true	true	false	false	true	true	true	true
Plant pathogenicity	FALSE	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗
Hemolysis	gamma	gamma ✓	beta ✗	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓

Back to Search