Acinetobacter guerrae

General Information

Acinetobacter guerrae is a member of the genus Acinetobacter, which is known for its remarkable ability to survive in a variety of environments, including soil, water, and hospital settings. This adaptability makes Acinetobacter guerrae particularly interesting from a research perspective. One of the key characteristics of this species is its potential for antibiotic resistance, a trait that is common among Acinetobacter species and poses significant challenges in clinical settings. Acinetobacter guerrae is also notable for its metabolic versatility. It can utilize a wide range of organic compounds as carbon sources, which underscores its ecological flexibility and potential for bioremediation applications. This metabolic adaptability is a subject of ongoing research, as understanding the pathways and mechanisms involved could lead to novel biotechnological applications. Another important aspect of Acinetobacter guerrae is its role in horizontal gene transfer. This species, like other Acinetobacter members, can acquire and disseminate genetic material, including antibiotic resistance genes, through mechanisms such as transformation. This ability to exchange genetic information makes it a valuable model organism for studying microbial evolution and the spread of resistance traits. In summary, Acinetobacter guerrae is a microorganism of significant interest due to its antibiotic resistance potential, metabolic versatility, and role in horizontal gene transfer. These characteristics not only make it a challenging pathogen in clinical settings but also a promising candidate for various research and biotechnological applications.

Acinetobacter guerrae is a species of the genus Acinetobacter, which is known for its remarkable adaptability and resilience in various environments. This organism is particularly interesting due to its ability to thrive in both clinical and environmental settings, making it a subject of significant research interest. One of the most notable characteristics of A. guerrae is its potential role in antibiotic resistance. This species has been isolated from various sources, including soil and clinical specimens, which raises important questions about its ecological niche and its implications for public health. The genome of A. guerrae has been studied to understand its metabolic pathways and resistance mechanisms, providing insights into how it can survive in hostile environments, such as those containing antibiotics. This research is crucial for developing strategies to combat infections caused by multidrug-resistant organisms. Furthermore, A. guerrae has been linked to opportunistic infections, particularly in immunocompromised patients, highlighting its clinical relevance. In addition to its medical significance, A. guerrae serves as a model organism for studying microbial ecology and evolution. Its ability to exchange genetic material with other bacteria contributes to the understanding of horizontal gene transfer, which is a key factor in the spread of antibiotic resistance. Overall, Acinetobacter guerrae stands out as a valuable organism for both clinical and environmental microbiology research, offering insights that could lead to better management of antibiotic resistance and improved treatment options for infections.

Taxonomy

Superkingdom: Bacteria

Phylum: Pseudomonadota

Class: Gammaproteobacteria

Order: Moraxellales

Family: Moraxellaceae

Genus: Acinetobacter

Species: Acinetobacter guerrae

NCBI ID

1843371

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCF/009/372/255/GCF_009372255.1_ASM937225v1

File for sequence-based predictions:
GCF_009372255.1_ASM937225v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The bacterium Acinetobacter guerrae is a member of the Acinetobacter genus, which is known for its clinical significance, particularly in hospital settings. This organism has been associated with various infections, including pneumonia, bloodstream infections, and wound infections. Its relevance in human health is underscored by its ability to cause opportunistic infections, especially in immunocompromised patients or those with underlying health conditions. One of the critical aspects of Acinetobacter guerrae is its pathogenicity. It can adhere to surfaces and form biofilms, which contribute to its survival in hospital environments and its ability to evade the immune response. This biofilm formation is particularly problematic in medical devices, leading to persistent infections that are difficult to treat. Moreover, Acinetobacter guerrae is notable for its antimicrobial resistance. Many strains exhibit resistance to multiple classes of antibiotics, including beta-lactams, aminoglycosides, and fluoroquinolones. This resistance poses significant challenges in clinical management, as infections caused by this organism can be difficult to treat and may require the use of last-resort antibiotics, such as polymyxins. In terms of medical applications, while Acinetobacter guerrae itself is not used therapeutically, understanding its mechanisms of resistance and pathogenicity can inform the development of new treatment strategies and infection control measures. Research into its interactions with the human body and its immune evasion strategies is ongoing, with the aim of improving outcomes for patients affected by infections caused by this organism. Overall, Acinetobacter guerrae represents a significant concern in clinical microbiology, particularly due to its role in nosocomial infections, its potential for antimicrobial resistance, and the challenges it presents in patient management.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Acinetobacter guerrae is a species of bacteria that is primarily associated with urban environments and hospital settings. This microorganism is often found in soil and water systems, where it can thrive in various ecological niches. Its adaptability allows it to survive in nutrient-rich environments, often linked to human activity, such as agricultural runoff or wastewater treatment facilities. In hospital environments, A. guerrae is notable for its role in nosocomial infections, where it can be a significant opportunistic pathogen. It is commonly found on surfaces and medical equipment, highlighting its ability to persist in high-stress environments. This bacterium can form biofilms, which contribute to its resistance against disinfectants and antibiotics, making it a concern for infection control. Furthermore, A. guerrae exhibits symbiotic relationships with other microorganisms, particularly in biofilm communities, where it can interact with both beneficial and pathogenic species. Its presence in these communities can influence nutrient cycling and microbial dynamics, showcasing its role in the broader ecosystem. Overall, Acinetobacter guerrae thrives in disturbed habitats influenced by human activity, demonstrating its ecological versatility and importance in both natural and anthropogenic environments.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Acinetobacter guerrae has shown significant potential in various industrial applications. One of the most notable areas is in biotechnology, where Acinetobacter guerrae is utilized for its ability to degrade a wide range of pollutants, making it valuable in waste management processes. This organism can effectively break down hydrocarbons and other toxic compounds, which is crucial for bioremediation efforts in contaminated environments. In the realm of biofuel production, Acinetobacter guerrae has been studied for its capacity to produce lipids that can be converted into biodiesel. The organism's metabolic pathways allow it to accumulate fatty acids, which can be harvested and processed through fermentation techniques to yield biofuels, thus contributing to sustainable energy solutions. Furthermore, Acinetobacter guerrae has potential applications in pharmaceutical development. Its enzymatic activities can be harnessed for the production of bioactive compounds, which may lead to the discovery of new drugs or therapeutic agents. The organism's ability to produce specific enzymes can facilitate enzyme production processes that are essential in the synthesis of pharmaceuticals. Overall, Acinetobacter guerrae demonstrates versatility across multiple industries, particularly in biodegradation, waste treatment, and biofuel production, making it a valuable microorganism for future industrial applications.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 8

LLM predicted phenotypes: 5

Phenotype	High-quality annotation	anthropic/claude-3.5-sonnet	mistralai/mixtral-8x7b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	google/gemini-pro	anthropic/claude-3-haiku:beta	meta-llama/llama-3-70b-instruct:nitro	openchat/openchat-7b	mistralai/mistral-7b-instruct	google/gemini-flash-1.5	google/gemini-flash-1.5	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	google/gemini-pro-1.5	google/gemini-pro-1.5	openai/gpt-4	openai/gpt-4	openai/gpt-4o	openai/gpt-4o	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	perplexity/llama-3-sonar-small-32k-chat	perplexity/llama-3-sonar-small-32k-chat	google/gemma-7b-it	google/gemma-7b-it
Motility	N/A	false	false	true	true	true	true	true	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	true	true	true	true	true	true
Gram staining	gram stain negative	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain variable ✗	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓
Aerophilicity	aerobic	aerobic ✓	facultatively anaerobic ✗	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	facultatively anaerobic ✗	facultatively anaerobic ✗	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	false ✓	true ✗	false ✓	true ✗	true ✗	false ✓	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗
Biofilm formation	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	N/A	true	false	true	true	true	true	false	false	true	true	true	true	true	true	false	false	true	true	true	true	false	false	true	true	true	true	true	true
Biosafety level	biosafety level 2	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓
Health association	N/A	true	true	true	true	true	true	true	false	true	true	false	false	true	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true
Host association	N/A	true	true	true	true	true	true	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	gamma	gamma ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	gamma ✓	gamma ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	bacillus ✓	coccus ✗	coccus ✗	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	bacillus ✓	bacillus ✓

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