Streptomyces fumanus

General Information

Streptomyces fumanus is a fascinating microorganism belonging to the genus Streptomyces, which is renowned for its prolific production of secondary metabolites. One of the most notable characteristics of S. fumanus is its ability to produce a variety of bioactive compounds, including antibiotics, antifungals, and antitumor agents. This makes it a valuable organism in the field of biotechnology and pharmaceutical research. The genus Streptomyces is well-known for its complex life cycle and the formation of mycelium, which is a network of filamentous cells. S. fumanus shares this trait, contributing to its ability to thrive in diverse environments, particularly in soil where it plays a crucial role in decomposing organic matter. The production of secondary metabolites by S. fumanus is of particular interest because these compounds have significant therapeutic potential. For instance, the antibiotics produced by S. fumanus can be effective against a range of bacterial pathogens, making it a key player in the development of new antimicrobial agents. Moreover, the genetic and metabolic pathways involved in the synthesis of these bioactive compounds are a subject of extensive research. Understanding these pathways can lead to the discovery of novel drugs and the improvement of existing ones. In summary, Streptomyces fumanus is a microorganism of great interest due to its ability to produce a wide array of bioactive compounds, its complex life cycle, and its significant role in natural ecosystems. Its contributions to biotechnology and medicine underscore its importance as a subject of ongoing scientific investigation.

Streptomyces fumanus is a fascinating actinobacterium known for its remarkable ability to produce a diverse array of bioactive compounds, which makes it a valuable organism in pharmaceutical research. This species is part of the larger genus Streptomyces, which is renowned for its role in natural antibiotic production. What sets S. fumanus apart is its unique metabolic pathways that allow it to synthesize novel secondary metabolites, some of which have shown promising antimicrobial and antifungal properties. One of the most interesting aspects of S. fumanus is its ecological role in soil environments, where it contributes to the decomposition of organic matter and the cycling of nutrients. This not only aids in soil health but also supports plant growth, making it an important player in agricultural ecosystems. The ability of S. fumanus to thrive in various environmental conditions highlights its adaptability and potential for biotechnological applications. Research into S. fumanus has also revealed its potential in bioremediation, as it can degrade various pollutants, including certain pesticides and heavy metals. This characteristic opens avenues for using this microorganism in environmental cleanup efforts, showcasing its dual role in both health and environmental sustainability. Overall, Streptomyces fumanus stands out as a promising candidate for further exploration in drug discovery and environmental biotechnology, making it a significant organism in microbiological research.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Kitasatosporales

Family: Streptomycetaceae

Genus: Streptomyces

Species: Streptomyces fumanus

NCBI ID

67302

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/014/655/295/GCA_014655295.1_ASM1465529v1

File for sequence-based predictions:
GCA_014655295.1_ASM1465529v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Streptomyces fumanus is a member of the genus Streptomyces, which is known for its significant role in the production of antibiotics and other bioactive compounds. While S. fumanus itself is not commonly associated with human disease, its relatives have been implicated in various clinical contexts. Antimicrobial resistance is a notable concern, as many Streptomyces species have developed mechanisms to resist the very antibiotics they produce, which can complicate treatment options for infections caused by other pathogens. In terms of human health, S. fumanus and its relatives are often studied for their potential as probiotics, contributing to gut health and possibly enhancing the immune response against certain pathogens. The production of secondary metabolites by S. fumanus may also have therapeutic applications, including the development of new drugs. However, the interaction of S. fumanus with the human body is not well-documented in terms of pathogenicity or disease associations. It is essential to note that while some Streptomyces species can be opportunistic pathogens, particularly in immunocompromised individuals, S. fumanus has not been directly linked to any significant outbreaks or infections. Overall, the clinical implications of Streptomyces fumanus primarily revolve around its potential benefits in antibiotic production and its role in the microbiome, rather than direct pathogenic effects.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Streptomyces fumanus is a species of actinobacteria that is primarily associated with soil ecosystems and decaying organic matter. This microorganism thrives in environments rich in organic material, where it plays a crucial role in the decomposition process. Its presence is often linked to the breakdown of complex organic compounds, contributing to nutrient cycling within the ecosystem. Soil Biomes: In soil biomes, Streptomyces fumanus is commonly found in the upper layers of the soil, where it interacts with various soil components, including minerals and other microorganisms. It is known for its ability to produce a wide range of bioactive compounds, which can inhibit the growth of pathogenic fungi and bacteria, thus playing a protective role in the soil microbiome. Symbiotic Relationships: This microorganism often engages in symbiotic relationships with plants, promoting plant health by enhancing nutrient availability and providing resistance against soil-borne pathogens. The metabolites produced by Streptomyces fumanus can stimulate plant growth and improve soil structure, making it an important player in agricultural ecosystems. Adaptation to Environmental Conditions: Streptomyces fumanus exhibits remarkable adaptability to varying environmental conditions, including changes in moisture and temperature. This adaptability allows it to thrive in diverse habitats, from tropical forests to temperate grasslands, where it contributes to the overall health and sustainability of these ecosystems. Its ability to degrade complex organic materials also makes it a key organism in composting processes, further emphasizing its ecological significance.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Streptomyces fumanus has shown significant potential in various industrial applications. One of the most notable areas is in biotechnology, where Streptomyces fumanus is utilized for its ability to produce a wide range of bioactive compounds, including antibiotics and enzymes. This capability is particularly valuable in the pharmaceutical industry, where the organism is involved in the fermentation process to synthesize these compounds, contributing to the development of new medications and therapeutic agents. In the realm of waste management, Streptomyces fumanus has demonstrated effectiveness in biodegradation processes. It can break down complex organic materials, making it useful for the treatment of contaminated soils and wastewater. This biodegradation ability helps in the remediation of environments polluted with organic pollutants, thus playing a crucial role in environmental sustainability. Additionally, Streptomyces fumanus is being explored for its potential in biofuel production. The organism's enzymatic activity can facilitate the breakdown of lignocellulosic biomass, which is a key step in the conversion of plant materials into fermentable sugars for bioethanol production. This process not only contributes to renewable energy sources but also aids in reducing reliance on fossil fuels. Overall, Streptomyces fumanus exemplifies the versatility of microbial applications across various industries, particularly in pharmaceutical development, waste treatment, and biofuel production, showcasing its importance in modern biotechnology.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 8

LLM predicted phenotypes: 5

Phenotype	High-quality annotation	google/gemini-flash-1.5	anthropic/claude-3.5-sonnet	google/palm-2-chat-bison-32k	meta-llama/llama-3-70b-instruct:nitro	google/gemini-pro	anthropic/claude-3-haiku:beta	perplexity/llama-3-sonar-small-32k-chat	microsoft/phi-3-mini-128k-instruct	mistralai/mistral-7b-instruct	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	meta-llama/llama-3-8b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	google/gemma-7b-it	google/gemma-7b-it	openchat/openchat-7b	openchat/openchat-7b	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mixtral-8x7b-instruct:nitro
Motility	N/A	false	false	false	false	false	false	true	false	true	false	false	false	false	true	true	false	false	false	false	false	false	true	true	false	false	false	false
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain variable ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerotolerant ✗	aerotolerant ✗	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	true ✗	false ✓	true ✗	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗
Biofilm formation	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 3 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 3 ✗	biosafety level 3 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	false	false	true	true	true	true	true	false	false	false	false	true	true	true	true	false	false	false	false	true	true	true	true	true	true	true	true
Host association	FALSE	true ✗	false ✓	false ✓	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓
Spore formation	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Hemolysis	N/A	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	N/A	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	coccus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus

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