Streptomyces albaduncus

General Information

Streptomyces albaduncus is a fascinating microorganism belonging to the genus Streptomyces, which is renowned for its prolific production of secondary metabolites. One of the most notable characteristics of S. albaduncus is its ability to produce a wide array of bioactive compounds, including antibiotics, antifungals, and antitumor agents. This makes it an invaluable resource in pharmaceutical research and biotechnology. The genus Streptomyces is well-known for its complex life cycle and filamentous growth, which resembles that of fungi. S. albaduncus forms a dense, branched mycelium that can differentiate into spores, contributing to its resilience and adaptability in various environments. Another intriguing aspect of S. albaduncus is its potential in bioremediation. Members of the Streptomyces genus are known for their ability to degrade a variety of organic pollutants, and S. albaduncus is no exception. This capability is particularly valuable for environmental cleanup efforts, where microbial degradation of contaminants can be a sustainable and effective solution. In addition to its environmental and pharmaceutical applications, S. albaduncus is also of interest due to its genetic and metabolic diversity. The genome of S. albaduncus harbors numerous gene clusters responsible for the biosynthesis of its diverse secondary metabolites. This genetic wealth provides a treasure trove for researchers aiming to discover new drugs and understand microbial biosynthetic pathways. Overall, Streptomyces albaduncus stands out as a microorganism of significant scientific interest due to its prolific production of bioactive compounds, potential in bioremediation, and genetic diversity. Its study not only advances our understanding of microbial ecology and evolution but also holds promise for practical applications in medicine and environmental science.

Streptomyces albaduncus is a fascinating actinobacterium known for its remarkable ability to produce a variety of bioactive compounds, making it a valuable organism in pharmaceutical research. This species is part of the larger genus Streptomyces, which is renowned for its role in natural antibiotic production. One of the most interesting aspects of S. albaduncus is its potential to synthesize novel secondary metabolites that can be harnessed for therapeutic applications. The organism thrives in soil environments, contributing to the rich biodiversity of microbial life. Its ability to degrade complex organic materials allows it to play a crucial role in nutrient cycling within ecosystems. This ecological function not only highlights its importance in environmental microbiology but also underscores its potential in bioremediation efforts. Research has shown that S. albaduncus can produce compounds with antifungal, antibacterial, and even anticancer properties, making it a target for drug discovery. The unique metabolic pathways utilized by this species for secondary metabolite production are of particular interest to scientists, as they may lead to the identification of new drugs that can combat resistant strains of pathogens. Furthermore, the genetic and biochemical diversity within the Streptomyces genus, including S. albaduncus, provides a rich field for studying gene regulation and expression related to antibiotic biosynthesis. This makes S. albaduncus not only a key player in the search for new antibiotics but also a model organism for understanding the complexities of microbial secondary metabolism. Overall, Streptomyces albaduncus stands out as a significant organism in both ecological and biomedical research, with its contributions to our understanding of microbial interactions and potential therapeutic applications.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Kitasatosporales

Family: Streptomycetaceae

Genus: Streptomyces

Species: Streptomyces albaduncus

NCBI ID

68172

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/014/650/615/GCA_014650615.1_ASM1465061v1

File for sequence-based predictions:
GCA_014650615.1_ASM1465061v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Streptomyces albaduncus is a member of the genus Streptomyces, which is known for its significant role in the production of antibiotics and other bioactive compounds. This microorganism has been studied for its potential in antimicrobial therapy, particularly due to its ability to produce various secondary metabolites that exhibit antibacterial and antifungal properties. The clinical implications of Streptomyces albaduncus are primarily linked to its use in the development of novel therapeutics, especially in the context of increasing antimicrobial resistance observed in many pathogenic bacteria. In addition to its therapeutic potential, Streptomyces albaduncus may also play a role in human health through its contributions to the microbiome, although specific studies on its direct effects on human health are limited. Its interaction with the human body is not fully understood, but it is hypothesized that certain strains may have beneficial effects, potentially acting as probiotics or contributing to the overall balance of the gut microbiota. Furthermore, the organism's ability to evade the immune response is an area of interest, particularly in understanding how it can survive in various environments and its implications for human health. While there are no well-documented outbreaks or infections directly associated with Streptomyces albaduncus, its relatives in the Streptomyces genus have been implicated in opportunistic infections, particularly in immunocompromised individuals. Overall, the clinical relevance of Streptomyces albaduncus lies in its potential applications in pharmaceutical development and its contributions to our understanding of microbial interactions within the human body.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Streptomyces albaduncus is a species of bacterium that thrives primarily in soil ecosystems, particularly in nutrient-rich environments. This microorganism is commonly found in terrestrial biomes where it plays a crucial role in the decomposition of organic matter. Its ability to produce a variety of bioactive compounds makes it significant in the soil microbiome, contributing to nutrient cycling and soil health. Ecological Niches: - _Streptomyces albaduncus occupies a niche as a decomposer, breaking down complex organic materials such as plant debris and dead organisms. This process not only recycles nutrients back into the soil but also enhances soil structure and fertility. - It is often associated with rhizosphere environments, where it interacts with plant roots, promoting plant growth through the production of growth-promoting substances and enhancing nutrient availability. Notable Interactions: - This bacterium is known for its antibiotic production, which can inhibit the growth of competing microorganisms, thus allowing it to thrive in its habitat. This characteristic also makes it a subject of interest in pharmaceutical research for the development of new antibiotics. - Streptomyces albaduncus may engage in symbiotic relationships with certain plants, aiding in their growth while benefiting from the organic compounds released by the roots. Overall, Streptomyces albaduncus is an essential component of soil ecosystems, contributing to ecological balance and health through its various roles in nutrient cycling, plant interactions, and microbial competition.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Streptomyces albaduncus is known for its significant contributions to various industrial applications. One of the primary areas is in biotechnology, where it is utilized for its ability to produce a wide range of bioactive compounds, including antibiotics and enzymes. This organism is particularly noted for its role in fermentation, which is a critical process in the production of pharmaceuticals and other bioactive substances. In the realm of waste management, Streptomyces albaduncus has demonstrated capabilities in biodegradation, where it can break down complex organic materials, thus aiding in the treatment of waste and reducing environmental pollution. Its enzymatic activity is particularly valuable in this context, as it can facilitate the breakdown of pollutants and contribute to the detoxification of contaminated environments. Moreover, Streptomyces albaduncus has potential applications in biofuel production. Through its metabolic processes, it can assist in the conversion of biomass into biofuels, making it a candidate for sustainable energy solutions. The organism's ability to produce enzymes that degrade lignocellulosic materials is particularly beneficial in this area, enhancing the efficiency of biofuel production processes. In summary, Streptomyces albaduncus plays a vital role in pharmaceutical development, waste management, and biofuel production, showcasing its versatility and importance in various industrial sectors through processes such as fermentation, biodegradation, and enzyme production.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	google/gemini-flash-1.5	openai/gpt-3.5-turbo-0125	meta-llama/llama-3-70b-instruct:nitro	google/gemini-pro	meta-llama/llama-3-8b-instruct:nitro	anthropic/claude-3-haiku:beta	openchat/openchat-7b	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	anthropic/claude-3.5-sonnet	anthropic/claude-3.5-sonnet	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	perplexity/llama-3-sonar-small-32k-chat	perplexity/llama-3-sonar-small-32k-chat	google/gemma-7b-it	google/gemma-7b-it	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mistral-7b-instruct	mistralai/mistral-7b-instruct
Motility	N/A	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	true	true	true	true	true	true	false	false	false	false
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	false ✓	true ✗	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗
Biofilm formation	N/A	true	true	true	true	true	true	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false
Animal pathogenicity	FALSE	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 3 ✗	biosafety level 3 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	false	false	true	true	true	true	true	false	false	true	true	false	false	true	true	false	false	true	true	true	true	true	true	true	true	true	true	false	false
Host association	FALSE	true ✗	false ✓	true ✗	true ✗	true ✗	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Hemolysis	N/A	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	tail	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗

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