Streptomyces flavofungini

General Information

Streptomyces flavofungini is a fascinating microorganism belonging to the genus Streptomyces, which is renowned for its prolific production of secondary metabolites. One of the most notable characteristics of S. flavofungini is its ability to produce a variety of bioactive compounds, including antibiotics, antifungals, and enzymes. This makes it a valuable organism in the field of biotechnology and pharmaceutical research. Streptomyces species are well-known for their complex life cycle and filamentous growth, which is similar to that of fungi. This unique growth pattern allows them to thrive in diverse environments, particularly in soil where they play a crucial role in decomposing organic matter. The production of secondary metabolites by S. flavofungini is of particular interest because these compounds have potential applications in medicine and agriculture. For instance, antibiotics produced by Streptomyces species have been instrumental in treating bacterial infections, and the antifungal compounds can be used to protect crops from fungal pathogens. Moreover, S. flavofungini has been studied for its potential in bioremediation, the process of using microorganisms to degrade environmental pollutants. The enzymes produced by this species can break down complex organic compounds, making it a promising candidate for cleaning up contaminated environments. In summary, Streptomyces flavofungini is a microorganism of significant interest due to its ability to produce a wide range of bioactive compounds, its unique filamentous growth, and its potential applications in medicine, agriculture, and environmental remediation. These characteristics make it a valuable subject for ongoing research and development in various scientific fields.

Streptomyces flavofungini is a fascinating actinobacterium known for its remarkable ability to produce a variety of bioactive compounds, making it a valuable organism in pharmaceutical research. This species is particularly interesting due to its capacity to synthesize antibiotics, which are crucial in the fight against bacterial infections. The unique metabolic pathways of S. flavofungini allow it to generate compounds that exhibit antimicrobial, antifungal, and antitumor activities, highlighting its potential in drug discovery and development. One of the standout features of S. flavofungini is its ability to thrive in diverse environments, which contributes to its genetic diversity and the production of novel secondary metabolites. This adaptability not only enhances its survival but also increases the likelihood of discovering new compounds with therapeutic applications. Researchers are particularly interested in the genomic and biochemical pathways of S. flavofungini, as they may reveal insights into the mechanisms of natural product biosynthesis. Furthermore, the ecological role of S. flavofungini in soil environments is significant, as it contributes to nutrient cycling and the degradation of complex organic materials. This ecological function underscores the importance of studying this organism not only for its pharmaceutical potential but also for its role in maintaining soil health and ecosystem balance. Overall, Streptomyces flavofungini stands out as a promising candidate for further research in both microbiology and biotechnology.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Kitasatosporales

Family: Streptomycetaceae

Genus: Streptomyces

Species: Streptomyces flavofungini

NCBI ID

68200

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCF/030/388/665/GCF_030388665.1_ASM3038866v1

File for sequence-based predictions:
GCF_030388665.1_ASM3038866v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Streptomyces flavofungini is a member of the genus Streptomyces, which is known for its significant role in the production of antibiotics and other bioactive compounds. This microorganism has been studied for its potential in antimicrobial therapy, particularly due to its ability to produce various secondary metabolites that exhibit antimicrobial properties. One of the notable aspects of Streptomyces flavofungini is its production of the antibiotic flavofungin, which has shown effectiveness against a range of bacterial pathogens, making it a candidate for further research in the development of new antibiotics to combat antimicrobial resistance. In terms of pathogenicity, Streptomyces flavofungini is generally considered non-pathogenic to humans; however, its close relatives within the Streptomyces genus can occasionally be associated with opportunistic infections, particularly in immunocompromised individuals. The organism's ability to produce a variety of enzymes and metabolites may also play a role in its interactions with the human microbiome, potentially influencing immune responses. Furthermore, the exploration of Streptomyces flavofungini in the context of probiotics and therapeutics is ongoing, as its metabolites may contribute to gut health and overall human health. The organism's interactions with the human body, particularly in the gut microbiome, could provide insights into its potential benefits as a probiotic agent. Overall, while Streptomyces flavofungini is primarily recognized for its antibiotic production, its implications in human health, disease associations, and potential therapeutic applications warrant further investigation.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Streptomyces flavofungini is a species of actinobacteria commonly found in soil ecosystems and decaying organic matter. This microorganism thrives in environments rich in organic material, where it plays a crucial role in the decomposition process. Its ability to degrade complex organic compounds makes it an essential contributor to nutrient cycling within these biomes. Soil Biomes: In terrestrial ecosystems, Streptomyces flavofungini is often associated with forest soils and agricultural lands. It forms a symbiotic relationship with plant roots, enhancing nutrient availability and promoting plant health through the production of various bioactive compounds. This interaction not only benefits the plants but also contributes to the overall biodiversity of the soil microbiome. Decaying Organic Matter: This microorganism is particularly adept at colonizing decaying plant material, where it helps break down cellulose and lignin, thus facilitating the recycling of nutrients back into the soil. Its presence in composting environments further underscores its role in organic waste management, making it a valuable organism in sustainable agricultural practices. Overall, Streptomyces flavofungini exemplifies the intricate relationships within terrestrial biomes, showcasing its importance in maintaining ecological balance and promoting soil health.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Streptomyces flavofungini is known for its significant contributions to various industrial applications. One of the primary areas is in biotechnology, where it is utilized for its ability to produce a range of bioactive compounds, including antibiotics and enzymes. This organism is particularly noted for its role in fermentation, which is a critical process in the production of pharmaceuticals and other bioactive substances. In the realm of waste management, Streptomyces flavofungini has demonstrated capabilities in biodegradation, effectively breaking down complex organic materials and pollutants in contaminated environments. This makes it a valuable asset in bioremediation efforts, where it can help restore ecosystems affected by industrial waste. Additionally, Streptomyces flavofungini is being explored for its potential in biofuel production. Its metabolic pathways can be harnessed to convert biomass into biofuels through fermentation processes, contributing to sustainable energy solutions. Overall, the versatility of Streptomyces flavofungini in these applications highlights its importance in advancing pharmaceutical development, waste treatment, and renewable energy initiatives, showcasing its potential as a key player in the biotechnology industry.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	google/gemini-flash-1.5	google/gemini-flash-1.5	google/gemma-7b-it	google/gemini-pro	meta-llama/llama-3-8b-instruct:nitro	anthropic/claude-3-haiku:beta	perplexity/llama-3-sonar-small-32k-chat	openchat/openchat-7b	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mistral-7b-instruct	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	anthropic/claude-3.5-sonnet	anthropic/claude-3.5-sonnet	google/gemini-pro-1.5	google/gemini-pro-1.5	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	openai/gpt-4	openai/gpt-4	meta-llama/llama-3-70b-instruct:nitro	meta-llama/llama-3-70b-instruct:nitro	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct
Motility	N/A	false	false	true	false	false	false	true	false	false	true	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false
Gram staining	gram stain positive	N/A	gram stain positive ✓	gram stain negative ✗	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain variable ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	N/A	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	true ✗	true ✗	false ✓	true ✗	true ✗	true ✗	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗
Biofilm formation	N/A	true	true	true	true	true	true	true	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗
Health association	N/A	false	false	true	true	true	true	true	false	true	false	false	false	true	true	true	true	true	true	true	true	true	true	false	false	true	true	false	false
Host association	FALSE	true ✗	true ✗	false ✓	false ✓	true ✗	false ✓	true ✗	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗
Spore formation	TRUE	true ✓	true ✓	false ✗	true ✓	true ✓	true ✓	true ✓	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Hemolysis	N/A	gamma	gamma	alpha	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	tail	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗

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