Streptomyces lomondensis

General Information

Streptomyces lomondensis is a fascinating microorganism belonging to the genus Streptomyces, which is renowned for its prolific production of secondary metabolites. One of the most intriguing aspects of S. lomondensis is its ability to produce a variety of bioactive compounds, including antibiotics, antifungals, and antitumor agents. This makes it a valuable organism in the field of biotechnology and pharmaceutical research. Key Characteristics: - Secondary Metabolite Production: S. lomondensis is particularly noted for its production of lomofungin, an antifungal compound that has shown effectiveness against a range of fungal pathogens. This ability to produce bioactive compounds is a hallmark of the Streptomyces genus and is of significant interest for drug discovery and development. - Genetic Diversity: The genetic makeup of S. lomondensis is rich and diverse, providing a wealth of genetic material that can be explored for novel genes and pathways involved in secondary metabolite biosynthesis. This genetic diversity is a key factor in its ability to produce a wide array of bioactive substances. - Ecological Role: In its natural habitat, S. lomondensis plays a crucial role in soil health and nutrient cycling. It contributes to the decomposition of organic matter and the suppression of soil-borne pathogens, thereby promoting plant health and soil fertility. - Research Potential: Due to its ability to produce a variety of bioactive compounds, S. lomondensis is a subject of extensive research. Scientists are particularly interested in its metabolic pathways and regulatory mechanisms, which could lead to the discovery of new drugs and therapeutic agents. In summary, Streptomyces lomondensis is a microorganism of significant interest due to its ability to produce a wide range of bioactive compounds, its genetic diversity, and its important ecological role. Its potential applications in biotechnology and pharmaceuticals make it a valuable subject for ongoing research.

Streptomyces lomondensis is a fascinating actinobacterium known for its remarkable ability to produce a variety of bioactive compounds, making it a valuable organism in pharmaceutical research. This species is particularly interesting due to its antimicrobial properties, which have been the subject of numerous studies aimed at discovering new antibiotics to combat resistant bacterial strains. The unique metabolic pathways of S. lomondensis allow it to synthesize secondary metabolites that exhibit potent activity against a range of pathogens, including fungi and bacteria. One of the standout features of S. lomondensis is its ability to thrive in diverse environmental conditions, which contributes to its ecological significance. Isolated from soil samples, this organism plays a crucial role in nutrient cycling and soil health, showcasing the importance of actinobacteria in terrestrial ecosystems. Moreover, the genetic and biochemical diversity of S. lomondensis provides a rich resource for biotechnological applications. Researchers are particularly interested in its potential for bioremediation, as it can degrade various environmental pollutants, including pesticides and heavy metals. This capability not only highlights its adaptability but also underscores its potential utility in environmental cleanup efforts. In summary, Streptomyces lomondensis stands out as a promising candidate for drug discovery and environmental applications, making it a significant focus of ongoing microbiological and biochemical research.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Kitasatosporales

Family: Streptomycetaceae

Genus: Streptomyces

Species: Streptomyces lomondensis

NCBI ID

68229

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/014/651/035/GCA_014651035.1_ASM1465103v1

File for sequence-based predictions:
GCA_014651035.1_ASM1465103v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Streptomyces lomondensis is a member of the genus Streptomyces, which is known for its significant role in the production of antibiotics and other bioactive compounds. While S. lomondensis itself is not widely recognized for causing infections in humans, its relatives are often associated with various clinical implications. Antimicrobial resistance is a notable concern, as many Streptomyces species produce antibiotics, but they can also harbor genes that confer resistance to these agents, complicating treatment options. In terms of human health, S. lomondensis may have potential applications in probiotics or as a source of novel therapeutic agents due to its ability to produce secondary metabolites. These metabolites can have beneficial effects, such as anti-inflammatory or antimicrobial properties, which could be harnessed in clinical settings. Moreover, the interaction of Streptomyces species with the human microbiome is an area of interest, as they may contribute to the overall balance of microbial communities, potentially influencing immune responses and overall health. However, the specific mechanisms of immune evasion or pathogenicity in S. lomondensis are not well-documented, and further research is needed to fully understand its clinical relevance. In summary, while Streptomyces lomondensis may not be directly linked to specific diseases or outbreaks, its relatives play crucial roles in antibiotic production and may have future applications in medicine, particularly in the context of antimicrobial resistance and therapeutics.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Streptomyces lomondensis is a species of actinobacteria commonly found in soil ecosystems and decaying organic matter. This microorganism thrives in environments rich in organic material, where it plays a crucial role in the decomposition process. Its ability to break down complex organic compounds contributes to nutrient cycling within the ecosystem, making it an essential player in maintaining soil health and fertility. In particular, Streptomyces lomondensis is often associated with terrestrial biomes, where it can be found in both temperate and tropical regions. The organism exhibits a remarkable capacity for environmental adaptation, allowing it to survive in varying conditions, including changes in moisture and nutrient availability. Notably, Streptomyces lomondensis engages in symbiotic relationships with plants, promoting plant growth through the production of bioactive compounds. These interactions can enhance plant resistance to pathogens and improve overall plant health, showcasing the organism's importance in agricultural ecosystems. Furthermore, this species is known for its production of various secondary metabolites, which can have antimicrobial properties. This characteristic not only aids in its survival by inhibiting competing microorganisms but also highlights its potential applications in biotechnology and pharmaceuticals. Overall, Streptomyces lomondensis exemplifies the intricate relationships within soil biomes, contributing to ecological balance and offering benefits that extend to agricultural practices and human health.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Streptomyces lomondensis has shown significant potential in various industrial applications due to its unique metabolic capabilities. One of the primary areas of interest is in biotechnology, where Streptomyces lomondensis is known for its ability to produce a range of bioactive compounds, including antibiotics and enzymes. This makes it a valuable organism in the development of new pharmaceuticals, particularly in the production of novel antimicrobial agents through fermentation processes. In the realm of waste management, Streptomyces lomondensis has demonstrated effective biodegradation capabilities, particularly in the breakdown of complex organic materials. This property can be harnessed for the treatment of industrial waste, where the organism can help in the degradation of pollutants, thus contributing to environmental sustainability. Moreover, the organism's enzymatic activity is noteworthy, as it can produce various enzymes that are useful in biofuel production. These enzymes can facilitate the conversion of biomass into fermentable sugars, which can then be further processed into biofuels. The use of Streptomyces lomondensis in this context highlights its role in the development of renewable energy sources. Overall, Streptomyces lomondensis stands out as a versatile microorganism with applications spanning pharmaceutical development, biotechnology, waste management, and biofuel production, making it a significant player in the industrial microbiology landscape.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 8

LLM predicted phenotypes: 5

Phenotype	High-quality annotation	google/palm-2-chat-bison-32k	google/gemini-flash-1.5	google/gemini-flash-1.5	meta-llama/llama-3-70b-instruct:nitro	anthropic/claude-3-haiku:beta	perplexity/llama-3-sonar-small-32k-chat	openchat/openchat-7b	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mistral-7b-instruct	google/gemini-pro	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	anthropic/claude-3.5-sonnet	anthropic/claude-3.5-sonnet	meta-llama/llama-3-8b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	google/gemma-7b-it	google/gemma-7b-it	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct
Motility	N/A	false	false	false	false	false	true	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	true	true	false	false
Gram staining	gram stain positive	gram stain positive ✓	N/A	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerotolerant ✗	aerotolerant ✗	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗
Biofilm formation	N/A	true	true	true	true	true	true	false	true	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	N/A	false	false	false	false	false	true	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	true	true	false	false
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 3 ✗	biosafety level 3 ✗	biosafety level 2 ✗	biosafety level 2 ✗
Health association	N/A	true	false	false	true	true	true	false	true	false	true	false	false	false	false	true	true	false	false	false	false	true	true	false	false	true	true	false	false
Host association	FALSE	false ✓	true ✗	true ✗	true ✗	false ✓	true ✗	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Spore formation	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Hemolysis	N/A	N/A	gamma	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	tail	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	spirillum ✗	spirillum ✗

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