Streptomyces novaecaesareae

General Information

Streptomyces novaecaesareae is a fascinating microorganism belonging to the genus Streptomyces, which is renowned for its prolific production of secondary metabolites. One of the most notable characteristics of S. novaecaesareae is its ability to produce a wide array of bioactive compounds, including antibiotics, antifungals, and antitumor agents. This makes it a valuable organism in the field of biotechnology and pharmaceutical research. Streptomyces species are known for their complex life cycle, which includes the formation of a mycelium and spore chains. This complex morphology is not only interesting from a biological standpoint but also plays a role in the organism's ability to produce secondary metabolites. The production of these compounds is often linked to the organism's developmental stages, making S. novaecaesareae an excellent model for studying the regulation of secondary metabolism. Another intriguing aspect of S. novaecaesareae is its ecological role. Streptomyces species are commonly found in soil and are known to play a crucial role in decomposing organic matter. This not only contributes to nutrient cycling in ecosystems but also positions S. novaecaesareae as a potential candidate for bioremediation efforts. Its ability to degrade complex organic compounds can be harnessed to clean up contaminated environments. In summary, Streptomyces novaecaesareae is a microorganism of significant interest due to its prolific production of bioactive compounds, complex life cycle, and ecological importance. Its potential applications in biotechnology, pharmaceuticals, and environmental science make it a valuable subject for ongoing research.

Streptomyces novaecaesareae is a fascinating actinobacterium known for its remarkable ability to produce a diverse array of bioactive compounds, including antibiotics and antifungal agents. This species is part of the larger genus Streptomyces, which is renowned for its role in natural product biosynthesis. What makes S. novaecaesareae particularly interesting is its unique metabolic pathways that allow it to synthesize novel secondary metabolites, which are of great interest in pharmaceutical research. One of the standout features of S. novaecaesareae is its ecological versatility; it can thrive in various environments, including soil and decaying organic matter, contributing to nutrient cycling and soil health. This adaptability not only highlights its ecological importance but also makes it a valuable organism for biotechnological applications, such as bioremediation and sustainable agriculture. Furthermore, the genomic analysis of S. novaecaesareae has revealed a rich repertoire of biosynthetic gene clusters, suggesting the potential for discovering new compounds with therapeutic properties. The ongoing research into its genetic makeup and metabolic capabilities positions S. novaecaesareae as a promising candidate for drug discovery and development, particularly in the face of rising antibiotic resistance. In summary, Streptomyces novaecaesareae stands out due to its prolific production of bioactive compounds, ecological significance, and potential applications in medicine and biotechnology, making it a subject of great interest in microbiological and pharmaceutical research.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Kitasatosporales

Family: Streptomycetaceae

Genus: Streptomyces

Species: Streptomyces novaecaesareae

NCBI ID

68244

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/000/716/875/GCA_000716875.1_ASM71687v1

File for sequence-based predictions:
GCA_000716875.1_ASM71687v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Streptomyces novaecaesareae is a member of the genus Streptomyces, which is known for its significant role in the production of antibiotics and other bioactive compounds. This species has been studied for its potential in antimicrobial resistance and its ability to produce various secondary metabolites that may have therapeutic applications. Clinical implications of Streptomyces novaecaesareae include its involvement in the production of natural antibiotics, which can be crucial in the fight against multi-drug resistant pathogens. In terms of human health, Streptomyces species are often found in soil and are part of the normal microbiota in various environments, contributing to the ecological balance. However, some strains can be opportunistic pathogens, particularly in immunocompromised individuals, leading to infections that may require careful management. The organism's ability to evade the immune response is an area of interest, as it may possess mechanisms that allow it to survive in hostile environments, including the human body. This characteristic can complicate treatment options, especially in cases where the organism is involved in chronic infections. Furthermore, the potential use of Streptomyces novaecaesareae in probiotics and therapeutics is being explored, given its ability to produce compounds that can modulate the immune system and promote health. Overall, while Streptomyces novaecaesareae is primarily recognized for its beneficial roles in antibiotic production, its implications in pathogenicity and resistance warrant further investigation to fully understand its clinical relevance.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Streptomyces novaecaesareae is a species of actinobacteria commonly found in soil ecosystems and marine environments. This microorganism thrives in nutrient-rich substrates, often associated with decaying organic matter, where it plays a crucial role in the decomposition process. Its ability to produce a variety of bioactive compounds contributes to its ecological significance, particularly in the soil biome, where it aids in nutrient cycling and enhances soil fertility through the breakdown of complex organic materials. In marine habitats, Streptomyces novaecaesareae has been isolated from sediments, indicating its adaptability to saline conditions. This organism is known for its symbiotic relationships with various plants, promoting growth and resistance to pathogens through the production of antimicrobial substances. Its interactions with other microorganisms in the soil and marine environments highlight its role in microbial communities, where it can influence the dynamics of these ecosystems. Overall, Streptomyces novaecaesareae exemplifies the intricate connections within terrestrial and aquatic biomes, showcasing its importance in maintaining ecological balance and supporting biodiversity.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Streptomyces novaecaesareae is known for its significant contributions to various industrial applications, particularly in the fields of biotechnology and pharmaceutical development. This organism is a member of the Streptomyces genus, which is renowned for its ability to produce a wide range of bioactive compounds, including antibiotics and enzymes. In pharmaceutical development, Streptomyces novaecaesareae has been studied for its potential to produce novel antibiotics, which are crucial in combating antibiotic-resistant bacteria. The organism's ability to undergo fermentation processes allows for the extraction and purification of these valuable compounds, making it a key player in the pharmaceutical industry. Additionally, Streptomyces novaecaesareae has shown promise in biodegradation applications, particularly in the breakdown of complex organic materials. This capability is essential in waste management, where the organism can be utilized to degrade pollutants and organic waste, thus contributing to environmental sustainability. The enzymatic activity of Streptomyces novaecaesareae facilitates the biodegradation of various substrates, making it an effective agent in bioremediation efforts. Moreover, the potential of Streptomyces novaecaesareae in biofuel production is being explored, as its metabolic pathways may be harnessed to convert biomass into biofuels through fermentation processes. This could lead to more sustainable energy sources and reduce reliance on fossil fuels. Overall, Streptomyces novaecaesareae exemplifies the versatility of microorganisms in industrial applications, particularly in biotechnology, waste management, and pharmaceutical development, showcasing its importance in modern bioprocessing and environmental solutions.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	google/gemini-pro-1.5	anthropic/claude-3.5-sonnet	google/gemini-flash-1.5	google/gemini-flash-1.5	anthropic/claude-3-haiku:beta	perplexity/llama-3-sonar-small-32k-chat	google/gemma-7b-it	openchat/openchat-7b	mistralai/mixtral-8x7b-instruct:nitro	google/gemini-pro	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	openai/gpt-4	openai/gpt-4	meta-llama/llama-3-70b-instruct:nitro	meta-llama/llama-3-70b-instruct:nitro	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	meta-llama/llama-3-8b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	mistralai/mistral-7b-instruct	mistralai/mistral-7b-instruct
Motility	N/A	false	false	false	false	false	true	true	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗
Biofilm formation	N/A	true	true	true	true	true	true	true	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false
Animal pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 3 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	true	true	false	false	true	true	true	false	true	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true	false	false	false	false
Host association	FALSE	true ✗	true ✗	true ✗	true ✗	false ✓	true ✗	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Hemolysis	N/A	N/A	N/A	gamma	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	tail	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗

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