Mycobacteroides immunogenum

General Information

Mycobacteroides immunogenum is a fascinating microorganism that has garnered significant attention in the scientific community due to its unique characteristics and implications in various fields. This species is particularly notable for its association with hypersensitivity pneumonitis, a condition that affects individuals exposed to contaminated metalworking fluids. The ability of M. immunogenum to thrive in such environments makes it a subject of interest for occupational health research. One of the most intriguing aspects of M. immunogenum is its resilience and adaptability. It can survive in harsh conditions, including environments with high levels of biocides, which are commonly used to control microbial growth in industrial settings. This resilience is partly due to its robust cell wall structure and metabolic versatility, allowing it to utilize a wide range of carbon sources. From a biotechnological perspective, M. immunogenum is valuable for its potential in bioremediation. Its ability to degrade complex hydrocarbons and other organic pollutants makes it a candidate for cleaning up contaminated environments. Additionally, its unique metabolic pathways are of interest for the development of novel biocatalysts. In the realm of microbial ecology, M. immunogenum serves as a model organism for studying microbial interactions and community dynamics in industrial and natural environments. Its interactions with other microorganisms, including both competitive and symbiotic relationships, provide insights into the complex web of microbial life. Overall, Mycobacteroides immunogenum stands out due to its clinical relevance, environmental resilience, and biotechnological potential, making it a valuable subject for ongoing research and application.

Mycobacteroides immunogenum is a fascinating member of the Mycobacteriaceae family, notable for its unique ecological niche and potential implications in human health. This organism is primarily found in the gastrointestinal tracts of various animals, particularly ruminants, which suggests a role in the digestion of complex carbohydrates and the maintenance of gut health. Its ability to thrive in such environments highlights its adaptability and potential symbiotic relationships with host organisms. One of the most intriguing aspects of M. immunogenum is its immunomodulatory properties. Research has indicated that this microorganism may influence the immune response, which could have significant implications for understanding gut microbiota interactions and their effects on systemic immunity. This characteristic makes M. immunogenum a valuable subject for studies focused on autoimmune diseases, allergies, and other immune-related conditions. Furthermore, the organism's unique lipid composition, particularly the presence of mycolic acids, contributes to its distinctive biochemical properties. These lipids are not only crucial for the organism's structural integrity but also play a role in its interactions with the host immune system. The study of these lipids can provide insights into pathogen-host interactions and the development of novel therapeutic strategies. In summary, Mycobacteroides immunogenum stands out due to its ecological significance, potential health implications, and unique biochemical characteristics, making it a promising candidate for further research in microbiology and immunology.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Mycobacteriales

Family: Mycobacteriaceae

Genus: Mycobacteroides

Species: Mycobacteroides immunogenum

NCBI ID

83262

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCF/001/605/725/GCF_001605725.1_ASM160572v1

File for sequence-based predictions:
GCF_001605725.1_ASM160572v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Mycobacteroides immunogenum is a member of the Mycobacteriaceae family and has garnered attention due to its potential clinical implications. It is primarily known for its role in infections associated with immunocompromised individuals, particularly those with underlying conditions such as HIV/AIDS or those undergoing immunosuppressive therapy. The organism can be isolated from various clinical specimens, including respiratory and gastrointestinal samples, indicating its opportunistic nature. Pathogenicity is a significant concern, as Mycobacteroides immunogenum can cause pulmonary infections and has been implicated in soft tissue infections as well. Its ability to evade the immune response is partly attributed to its complex cell wall structure, which can hinder phagocytosis and contribute to chronic infection states. In terms of antimicrobial resistance, there is limited data available, but like many mycobacterial species, it may exhibit resistance to common antibiotics, complicating treatment options. This resistance underscores the importance of susceptibility testing in clinical settings. While Mycobacteroides immunogenum is not widely recognized for any specific medical applications such as probiotics or vaccines, its presence in the human microbiome suggests a potential role in maintaining gut health. However, further research is needed to fully understand its interactions with the human body and its implications for disease associations and therapeutics.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Mycobacteroides immunogenum is a species of bacteria that is primarily associated with the human gastrointestinal tract. This organism thrives in the anaerobic environments of the gut, where it plays a significant role in the complex microbial community. Its presence is often linked to the breakdown of complex carbohydrates and the fermentation processes that contribute to the overall health of the host's digestive system. In this biome, Mycobacteroides immunogenum interacts symbiotically with other gut microbiota, contributing to the maintenance of a balanced microbial ecosystem. It aids in the production of short-chain fatty acids, which are crucial for gut health and can influence the immune response of the host. This metabolic activity not only supports the host's nutrition but also helps in modulating inflammation and protecting against pathogenic organisms. Furthermore, Mycobacteroides immunogenum exhibits remarkable environmental adaptation capabilities, allowing it to thrive in varying conditions within the gut. Its ability to withstand changes in pH and nutrient availability underscores its importance in the dynamic environment of the gastrointestinal tract. Overall, this microorganism exemplifies the intricate relationships within the gut microbiome, highlighting its role in health and disease.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Mycobacteroides immunogenum has shown potential in various industrial applications, particularly in the fields of biotechnology and pharmaceutical development. This organism is known for its ability to produce unique metabolites that can be harnessed in the production of bioactive compounds. For instance, it has been studied for its role in fermentation, where it can contribute to the synthesis of valuable secondary metabolites that have antimicrobial properties. In the realm of waste management, Mycobacteroides immunogenum has demonstrated capabilities in biodegradation, particularly in the breakdown of complex organic materials. This makes it a candidate for use in bioremediation processes, where it can help in the detoxification of contaminated environments, such as soil and water, by degrading pollutants. Furthermore, its enzymatic activity is of interest in biofuel production, where it may assist in the conversion of biomass into fermentable sugars, thus facilitating the production of bioethanol. The organism's metabolic pathways can be optimized for enhanced yield in enzyme production, which is crucial for various industrial processes. Overall, Mycobacteroides immunogenum presents a promising avenue for research and application in these industries, particularly through its involvement in fermentation, biodegradation, and enzyme production, making it a valuable microorganism in the quest for sustainable industrial practices.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 8

LLM predicted phenotypes: 5

Phenotype	High-quality annotation	google/gemini-flash-1.5	google/gemma-7b-it	anthropic/claude-3-haiku:beta	perplexity/llama-3-sonar-small-32k-chat	mistralai/mixtral-8x7b-instruct:nitro	google/gemini-pro	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	anthropic/claude-3.5-sonnet	anthropic/claude-3.5-sonnet	meta-llama/llama-3-8b-instruct:nitro	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	openai/gpt-4	openai/gpt-4	meta-llama/llama-3-70b-instruct:nitro	meta-llama/llama-3-70b-instruct:nitro	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	openchat/openchat-7b	openchat/openchat-7b	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	mistralai/mistral-7b-instruct	mistralai/mistral-7b-instruct
Motility	N/A	false	true	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false
Gram staining	gram stain positive	gram stain positive ✓	gram stain negative ✗	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain positive ✓	N/A	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	N/A
Aerophilicity	aerobic	aerobic ✓	N/A	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	anaerobic ✗	anaerobic ✗	aerobic ✓	aerobic ✓	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	N/A	false	true	true	true	true	false	false	false	true	true	false	false	true	true	true	false	false	false	false	false	false	false	false	false	false	true	true	true	true
Biofilm formation	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓
Biosafety level	biosafety level 2	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 3 ✗	biosafety level 3 ✗	biosafety level 3 ✗	biosafety level 3 ✗
Health association	N/A	true	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true	true	false	false	true	true	true	true	true	true	false	false	true	true
Host association	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	N/A	N/A	alpha	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	coccus ✗	coccus ✗	bacillus ✓	bacillus ✓

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