Kurthia massiliensis

General Information

Kurthia massiliensis is a fascinating microorganism that has garnered attention due to its unique characteristics and potential applications in various fields. This bacterium was first isolated from human feces, indicating its presence in the human gut microbiome. One of the most intriguing aspects of K. massiliensis is its ability to thrive in diverse environments, which suggests a high level of adaptability and resilience. Genomic Insights: The genome of Kurthia massiliensis has been sequenced, revealing a wealth of information about its metabolic capabilities and potential functions within the gut ecosystem. The genomic data suggest that this bacterium possesses a variety of genes involved in carbohydrate metabolism, which could play a role in the digestion and fermentation of dietary fibers. This makes K. massiliensis particularly interesting for studies on gut health and nutrition. Biotechnological Potential: The metabolic versatility of Kurthia massiliensis opens up possibilities for its use in biotechnological applications. For instance, its ability to break down complex carbohydrates could be harnessed in the production of biofuels or in the development of probiotics aimed at improving digestive health. Additionally, the bacterium's resilience in different environments makes it a promising candidate for bioremediation efforts, where it could be used to degrade environmental pollutants. Clinical Relevance: While Kurthia massiliensis is not typically associated with pathogenicity, its presence in the human gut microbiome suggests it could have a role in maintaining gut health. Further research is needed to fully understand its interactions with other microbial species and its impact on the host. Understanding these interactions could lead to new insights into the prevention and treatment of gastrointestinal disorders. In summary, Kurthia massiliensis stands out due to its genomic richness, metabolic flexibility, and potential applications in biotechnology and medicine. Its study not only enhances our understanding of the human microbiome but also opens up new avenues for practical applications in health and industry.

Kurthia massiliensis is a fascinating bacterium that was first isolated from a human clinical sample, highlighting its potential relevance in medical microbiology. This organism is part of the genus Kurthia, which is known for its unique ecological niches and adaptability. One of the most interesting aspects of K. massiliensis is its ability to thrive in various environments, suggesting a versatile metabolic capacity that could be valuable for biotechnological applications. The genome of Kurthia massiliensis has been sequenced, revealing insights into its genetic makeup and potential pathways for nutrient utilization. This genomic information opens avenues for research into its metabolic processes, which may include the degradation of complex organic compounds. Such capabilities could make K. massiliensis a candidate for bioremediation efforts, particularly in environments contaminated with organic pollutants. Additionally, the organism's association with human samples raises questions about its role in human health and disease. Understanding the interactions between K. massiliensis and the human microbiome could provide valuable insights into its potential pathogenicity or beneficial effects. This duality makes it a subject of interest for researchers studying microbial ecology and host-microbe interactions. In summary, Kurthia massiliensis stands out due to its ecological versatility, potential biotechnological applications, and its implications in human health, making it a valuable organism for further research in microbiology and related fields.

Taxonomy

Superkingdom: Bacteria

Phylum: Bacillota

Class: Bacilli

Order: Bacillales

Family: Planococcaceae

Genus: Kurthia

Species: Kurthia massiliensis

NCBI ID

1033739

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/000/285/555/GCA_000285555.1_ASM28555v1

File for sequence-based predictions:
GCA_000285555.1_ASM28555v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The microorganism Kurthia massiliensis is a Gram-positive, rod-shaped bacterium that has been identified in clinical settings, particularly in cases of infections associated with immunocompromised patients. It is part of the normal flora of the human body but can become pathogenic under certain conditions. Clinical relevance includes its potential role in nosocomial infections, where it has been isolated from patients with underlying health issues, such as those undergoing invasive procedures or with prolonged hospital stays. One of the significant concerns regarding Kurthia massiliensis is its antimicrobial resistance. Reports indicate that this organism may exhibit resistance to multiple antibiotics, complicating treatment options for infected patients. This resistance is particularly concerning in the context of hospital-acquired infections, where effective antimicrobial therapy is crucial for patient recovery. In terms of immune evasion, Kurthia massiliensis may utilize various strategies to survive within the host, including the production of biofilms, which can protect it from both the host's immune response and antibiotic treatment. While there is limited information on specific outbreaks directly linked to Kurthia massiliensis, its presence in clinical specimens underscores the importance of monitoring this organism in healthcare settings. Further research is needed to fully understand its pathogenic mechanisms and potential role in human health and disease.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Kurthia massiliensis is a bacterium that has been primarily isolated from human clinical samples, particularly in cases of infections. This organism thrives in human-associated environments, where it can be found in various niches, including the gastrointestinal tract and oral cavity. Its presence in these habitats suggests a role in the complex microbial communities that inhabit the human body. In terms of ecological interactions, K. massiliensis may engage in symbiotic relationships with other microorganisms, contributing to the overall balance of the microbiome. It can play a role in nutrient cycling and may assist in the breakdown of organic matter, which is crucial for maintaining the health of the host. Additionally, this bacterium has shown the ability to adapt to varied environmental conditions, which is essential for its survival in the dynamic environments of the human body. Its resilience and adaptability highlight its potential significance in pathogenic scenarios, where it may contribute to disease processes or interact with the immune system. Overall, Kurthia massiliensis exemplifies the intricate relationships microorganisms have within their biomes, particularly in human-associated ecosystems, where they can influence health and disease.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Kurthia massiliensis has shown potential in various industrial applications that leverage its unique metabolic capabilities. One of the most notable areas is in biotechnology, where Kurthia massiliensis can be utilized in fermentation processes to produce valuable metabolites. This organism is known for its ability to ferment a range of carbohydrates, making it a candidate for the production of organic acids and other biochemicals. In the realm of waste management, Kurthia massiliensis has been studied for its role in biodegradation processes. It can effectively break down complex organic materials, which is beneficial in treating wastewater and reducing environmental pollutants. This capability is particularly important in the context of bioremediation, where the organism can help in the detoxification of contaminated sites. Furthermore, the enzymatic activity of Kurthia massiliensis has implications in pharmaceutical development. The organism produces specific enzymes that can be harnessed for the synthesis of pharmaceutical compounds, enhancing the efficiency of drug production processes. Additionally, there is potential for Kurthia massiliensis in biofuel production. Its metabolic pathways can be explored to convert biomass into biofuels through fermentation, contributing to sustainable energy solutions. Overall, the diverse applications of Kurthia massiliensis highlight its significance in modern industrial processes, particularly in biotechnology, waste management, and energy production.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 10

LLM predicted phenotypes: 3

Phenotype	High-quality annotation	google/gemini-flash-1.5	google/gemini-pro	google/palm-2-chat-bison-32k	anthropic/claude-3-haiku:beta	meta-llama/llama-3-70b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	google/gemma-7b-it	openchat/openchat-7b	mistralai/mistral-7b-instruct	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	google/gemini-pro-1.5	google/gemini-pro-1.5	openai/gpt-4	openai/gpt-4	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mixtral-8x7b-instruct:nitro	openai/gpt-4o	openai/gpt-4o	anthropic/claude-3.5-sonnet	anthropic/claude-3.5-sonnet	meta-llama/llama-3-8b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b
Motility	N/A	false	false	true	false	true	true	true	false	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true	false	false	true	true
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain negative ✗	gram stain positive ✓	gram stain positive ✓	gram stain negative ✗	gram stain negative ✗	gram stain positive ✓	gram stain variable ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain negative ✗	N/A	gram stain positive ✓
Aerophilicity	aerobic	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	facultatively anaerobic ✗	facultatively anaerobic ✗	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	facultatively anaerobic ✗	facultatively anaerobic ✗	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Biofilm formation	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Animal pathogenicity	FALSE	false ✓	true ✗	false ✓	false ✓	true ✗	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗
Health association	N/A	false	true	true	false	true	true	true	false	false	false	false	true	true	false	false	true	true	true	true	true	true	true	true	false	false	true	true
Host association	FALSE	false ✓	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Spore formation	TRUE	true ✓	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗
Hemolysis	N/A	gamma	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	bacillus ✓	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓

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