Thomasclavelia ramosa

General Information

Thomasclavelia ramosa is a fascinating microorganism that has garnered attention due to its unique phylogenetic placement and potential implications for human health. This bacterium belongs to the family Lachnospiraceae, which is known for its role in the human gut microbiome. One of the most intriguing aspects of T. ramosa is its ability to produce short-chain fatty acids (SCFAs), such as butyrate, which are crucial for maintaining gut health and have anti-inflammatory properties. Thomasclavelia ramosa has a distinctive branching morphology, which is relatively rare among gut bacteria and contributes to its name, with ramosa meaning 'branched'. This morphological trait can be particularly useful in identifying the bacterium under a microscope. From a research perspective, T. ramosa is valuable due to its potential role in modulating the gut environment. Studies suggest that it may influence the composition of the gut microbiota and contribute to the overall metabolic health of the host. Its ability to interact with other gut microbes and host cells makes it a key player in the complex ecosystem of the human gut. Furthermore, Thomasclavelia ramosa has been isolated from various environments, indicating its adaptability and resilience. This adaptability could provide insights into how gut bacteria survive and thrive under different conditions, which is crucial for developing probiotics and other therapeutic interventions. In summary, Thomasclavelia ramosa stands out due to its unique morphology, its role in producing beneficial SCFAs, and its potential impact on gut health. These characteristics make it a significant subject of study in microbiome research and its applications in health and disease.

Thomasclavelia ramosa is a fascinating member of the microbial world, notable for its unique ecological niche and metabolic capabilities. This organism is primarily found in marine environments, particularly in association with marine invertebrates, which highlights its role in the complex interactions within these ecosystems. What makes T. ramosa particularly interesting is its ability to degrade complex organic compounds, which positions it as a potential candidate for bioremediation efforts in polluted marine habitats. The organism exhibits a distinctive filamentous morphology, which allows it to form intricate networks that can enhance nutrient absorption and facilitate interactions with other microorganisms. This characteristic not only aids in its survival but also contributes to the overall health of the marine microbiome. Furthermore, T. ramosa has been the subject of research due to its potential applications in biotechnology, particularly in the production of bioactive compounds. These compounds may possess antimicrobial properties, making T. ramosa a valuable resource for pharmaceutical development. The exploration of its genetic and metabolic pathways could unveil novel enzymes and metabolites that are beneficial for various industrial applications. In summary, Thomasclavelia ramosa stands out due to its ecological significance, unique morphological traits, and promising biotechnological applications, making it a compelling subject for further research in marine microbiology and environmental science.

Taxonomy

Superkingdom: Bacteria

Phylum: Bacillota

Class: Erysipelotrichia

Order: Erysipelotrichales

Family: Coprobacillaceae

Genus: Thomasclavelia

Species: Thomasclavelia ramosa

NCBI ID

1547

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/016/728/785/GCA_016728785.1_ASM1672878v1

File for sequence-based predictions:
GCA_016728785.1_ASM1672878v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The microorganism Thomasclavelia ramosa is a member of the phylum Bacteroidetes and has been identified in various environmental and clinical settings. While specific clinical implications of Thomasclavelia ramosa are not extensively documented, its presence in human microbiota suggests potential roles in human health and disease associations. It is primarily found in the gastrointestinal tract, where it may contribute to the maintenance of a balanced microbiome. However, its exact role in pathogenicity remains unclear, as it has not been definitively linked to any specific infections or diseases in humans. Research into related species within the same genus indicates that members of the Bacteroidetes phylum can exhibit antimicrobial resistance mechanisms, which may be a concern in clinical settings. The potential for immune evasion strategies, although not specifically documented for Thomasclavelia ramosa, is a common trait among many gut bacteria, allowing them to persist in the host despite immune challenges. Furthermore, the exploration of the gut microbiome has led to interest in the therapeutic applications of various bacteria, including the potential use of probiotics. While Thomasclavelia ramosa itself has not been directly studied for such applications, its relatives may offer insights into developing therapeutics aimed at restoring gut health or preventing diseases associated with dysbiosis. Overall, while Thomasclavelia ramosa is not currently recognized as a significant pathogen, its role in the microbiome and potential implications for human health warrant further investigation.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Thomasclavelia ramosa is a filamentous bacterium commonly found in marine environments, particularly in coastal waters and sediments. This microorganism thrives in nutrient-rich habitats, often associated with decaying organic matter, where it plays a crucial role in the decomposition process. Its presence is indicative of a healthy ecosystem, as it contributes to the cycling of nutrients and the breakdown of complex organic compounds. In these marine biomes, T. ramosa engages in symbiotic relationships with various marine organisms, including algae and invertebrates. This interaction not only aids in nutrient exchange but also enhances the overall productivity of the ecosystem. The bacterium's ability to adapt to varying salinity levels and temperature fluctuations allows it to occupy diverse niches within the intertidal zones and subtidal habitats. Furthermore, T. ramosa is known for its role in biofilm formation, which provides a protective environment for other microorganisms and contributes to the stability of the sediment structure. This characteristic is particularly important in estuarine ecosystems, where it helps maintain the balance of microbial communities and supports the health of the overall biome. Its adaptability and ecological functions underscore its significance in maintaining the integrity of marine ecosystems.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Thomasclavelia ramosa has shown potential in various industrial applications, particularly in the fields of biotechnology, waste management, and biofuel production. This organism is known for its ability to thrive in extreme environments, which can be harnessed for specific industrial processes. In biotechnology, Thomasclavelia ramosa can be utilized in fermentation processes to produce valuable metabolites. Its unique metabolic pathways allow for the conversion of substrates into bioactive compounds, which can be used in food and pharmaceutical industries. In the realm of waste management, this microorganism has demonstrated capabilities in biodegradation of complex organic materials. Its enzymatic activity enables the breakdown of pollutants, making it a candidate for bioremediation efforts in contaminated sites. This application is particularly relevant in treating industrial effluents and organic waste, contributing to a more sustainable waste management approach. Furthermore, Thomasclavelia ramosa has potential in biofuel production. By utilizing its metabolic processes, it can assist in the conversion of biomass into biofuels through fermentation of sugars derived from plant materials. This not only aids in renewable energy production but also helps in reducing reliance on fossil fuels. Overall, the diverse capabilities of Thomasclavelia ramosa in these industrial sectors highlight its significance as a valuable microorganism in advancing sustainable practices and innovative solutions.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 8

LLM predicted phenotypes: 5

Phenotype	High-quality annotation	google/palm-2-chat-bison-32k	google/gemini-flash-1.5	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mistral-7b-instruct	meta-llama/llama-3-8b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	meta-llama/llama-3-70b-instruct:nitro	openchat/openchat-7b	microsoft/phi-3-mini-128k-instruct	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	google/gemini-pro-1.5	google/gemini-pro-1.5	anthropic/claude-3.5-sonnet	anthropic/claude-3.5-sonnet	openai/gpt-4	openai/gpt-4	anthropic/claude-3-haiku:beta	anthropic/claude-3-haiku:beta	openai/gpt-4o	openai/gpt-4o	google/gemma-7b-it	google/gemma-7b-it	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	google/gemini-pro	google/gemini-pro
Motility	N/A	false	true	false	false	true	true	true	false	false	true	true	false	false	true	true	false	false	true	true	false	false	true	true	false	false	false	false
Gram staining	gram stain positive	gram stain negative ✗	gram stain negative ✗	gram stain negative ✗	gram stain variable ✗	gram stain negative ✗	gram stain negative ✗	gram stain positive ✓	gram stain negative ✗	gram stain negative ✗	N/A	gram stain negative ✗	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain negative ✗	N/A	gram stain negative ✗	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain negative ✗	N/A	gram stain negative ✗
Aerophilicity	anaerobic	anaerobic ✓	N/A	facultatively anaerobic ✗	aerotolerant ✗	N/A	N/A	N/A	N/A	N/A	facultatively anaerobic ✗	facultatively anaerobic ✗	aerobic ✗	aerobic ✗	aerobic ✗	aerobic ✗	anaerobic ✓	anaerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓
Biofilm formation	N/A	false	true	true	false	true	true	true	false	false	true	true	false	false	true	true	false	false	true	true	true	true	true	true	true	true	false	false
Animal pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓
Biosafety level	biosafety level 2	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗
Health association	N/A	false	false	true	false	true	true	true	false	false	false	false	true	true	true	true	false	false	true	true	true	true	true	true	true	true	true	true
Host association	TRUE	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	N/A	N/A	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	beta	beta	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	N/A	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	coccus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	coccus	coccus	bacillus	bacillus

Back to Search