Listeria ivanovii

General Information

Listeria ivanovii is a fascinating microorganism primarily due to its pathogenicity and its role in veterinary medicine. Unlike its more notorious relative, Listeria monocytogenes, which is a significant human pathogen, L. ivanovii is predominantly associated with infections in animals, particularly ruminants such as sheep and cattle. This species is of great interest to researchers studying zoonotic diseases and the mechanisms of bacterial infection in different hosts. One of the unique characteristics of L. ivanovii is its ability to cause septicemia and abortion in infected animals, which can have substantial economic impacts on livestock industries. The organism's pathogenicity is attributed to its production of various virulence factors, including listeriolysin O, which allows it to escape from the phagosome into the cytoplasm of host cells, thereby evading the host's immune response. From a research perspective, L. ivanovii serves as an important model for understanding the genus Listeria as a whole. Its comparative study with L. monocytogenes helps elucidate the genetic and molecular basis of host specificity and virulence. Additionally, L. ivanovii has been used in the development of novel vaccines and therapeutic strategies aimed at controlling listeriosis in both animals and humans. In summary, Listeria ivanovii is a valuable organism for scientific research due to its distinct pathogenic profile, economic impact on agriculture, and its role in advancing our understanding of bacterial pathogenesis and host-pathogen interactions.

Listeria ivanovii is a species of the genus Listeria, notable for its role as a foodborne pathogen, particularly in livestock and occasionally in humans. This organism is particularly interesting due to its ability to thrive in a variety of environments, including those with low temperatures, which makes it a significant concern in food safety, especially in refrigerated products. Its resilience to cold temperatures allows it to survive and multiply in food products that are stored in refrigeration, posing a risk for contamination. One of the unique aspects of Listeria ivanovii is its genetic similarity to Listeria monocytogenes, the more widely recognized pathogenic species. This similarity provides valuable insights into the evolution and pathogenic mechanisms of the Listeria genus. Research into L. ivanovii can enhance our understanding of the virulence factors that contribute to the pathogenicity of Listeria species, which is crucial for developing effective prevention and control strategies in food safety. Additionally, Listeria ivanovii has been studied for its potential use in biotechnological applications, particularly in the field of vaccine development. Its ability to invade host cells and elicit immune responses makes it a candidate for research into novel vaccine delivery systems. This characteristic underscores the organism's potential value beyond its pathogenicity, highlighting its dual role in both health and biotechnological research. Overall, Listeria ivanovii serves as a significant model organism for studying foodborne pathogens, their environmental resilience, and their implications for public health and safety.

Taxonomy

Superkingdom: Bacteria

Phylum: Bacillota

Class: Bacilli

Order: Bacillales

Family: Listeriaceae

Genus: Listeria

Species: Listeria ivanovii

NCBI ID

1638

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCF/037/062/565/GCF_037062565.1_ASM3706256v1

File for sequence-based predictions:
GCF_037062565.1_ASM3706256v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Listeria ivanovii is a pathogenic bacterium closely related to Listeria monocytogenes, known for its role in foodborne illnesses. It primarily affects animals but has been associated with infections in humans, particularly in immunocompromised individuals. Clinical implications of Listeria ivanovii include its potential to cause listeriosis, a serious infection that can lead to severe complications such as meningitis and septicemia. While Listeria monocytogenes is the more common cause of listeriosis, Listeria ivanovii has been documented in rare cases, particularly in patients with underlying health conditions. The pathogenicity of Listeria ivanovii is attributed to its ability to invade host cells and evade the immune response. It employs various strategies, such as the secretion of virulence factors that facilitate intracellular survival and replication. This ability to survive within host cells allows it to avoid detection by the immune system, contributing to its pathogenic potential. In terms of antimicrobial resistance, there is limited data on Listeria ivanovii, but like many bacteria, it may exhibit resistance to certain antibiotics, complicating treatment options. Preventive measures against listeriosis include proper food handling and cooking practices, as the organism is often found in contaminated food products. While Listeria ivanovii is not commonly used in medical applications, understanding its biology and pathogenic mechanisms can provide insights into the broader category of Listeria-related diseases, potentially informing the development of vaccines or therapeutics aimed at preventing listeriosis caused by both Listeria ivanovii and Listeria monocytogenes.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Listeria ivanovii has been studied for its potential applications in various industrial sectors, particularly in biotechnology and waste management. This organism is known for its ability to survive in harsh environments, which makes it a candidate for biodegradation processes. For instance, Listeria ivanovii can be involved in the breakdown of organic waste materials, contributing to the development of sustainable waste treatment solutions. In the realm of biofuel production, Listeria ivanovii has shown promise in the fermentation of agricultural residues, potentially leading to the generation of bioethanol. The organism's metabolic pathways can be harnessed to convert biomass into fermentable sugars, which can then be processed into biofuels through fermentation. Moreover, in pharmaceutical development, Listeria ivanovii has been investigated for its potential use in vaccine development due to its pathogenicity and ability to elicit immune responses. This could lead to the creation of novel vaccines that leverage the organism's unique properties. Overall, while Listeria ivanovii is primarily known for its pathogenicity, its industrial applications in biotechnology, waste management, and pharmaceuticals highlight its versatility and potential for contributing to various sectors through processes such as biodegradation and fermentation.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 8

LLM predicted phenotypes: 5

Phenotype	High-quality annotation	anthropic/claude-3.5-sonnet	google/gemini-flash-1.5	mistralai/mixtral-8x7b-instruct:nitro	google/gemini-pro	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	meta-llama/llama-3-70b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	openchat/openchat-7b	microsoft/phi-3-mini-128k-instruct	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	meta-llama/llama-3-8b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	openai/gpt-4	openai/gpt-4	anthropic/claude-3-haiku:beta	anthropic/claude-3-haiku:beta	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	google/gemma-7b-it	google/gemma-7b-it	mistralai/mistral-7b-instruct	mistralai/mistral-7b-instruct
Motility	N/A	true	true	false	true	true	true	true	true	true	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain variable ✗
Aerophilicity	facultatively anaerobic	facultatively anaerobic ✓	facultatively anaerobic ✓	facultatively anaerobic ✓	facultatively anaerobic ✓	facultatively anaerobic ✓	facultatively anaerobic ✓	facultatively anaerobic ✓	facultatively anaerobic ✓	facultatively anaerobic ✓	facultatively anaerobic ✓	N/A	N/A	N/A	N/A	facultatively anaerobic ✓	facultatively anaerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	true ✗	false ✓	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗
Biofilm formation	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Biosafety level	N/A	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2
Health association	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Host association	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	N/A	false	false	false	false	false	false	false	false	false	false	false	true	false	false	false	false	true	true	false	false	false	false	false	false	false	false	false	false
Hemolysis	beta	beta ✓	beta ✓	beta ✓	beta ✓	beta ✓	beta ✓	beta ✓	beta ✓	beta ✓	beta ✓	beta ✓	N/A	N/A	N/A	N/A	N/A	beta ✓	beta ✓	beta ✓	beta ✓	beta ✓	beta ✓	beta ✓	beta ✓	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓

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