Schaalia cardiffensis

General Information

Schaalia cardiffensis is a fascinating microorganism that belongs to the genus Schaalia, which is part of the family Actinomycetaceae. This bacterium is particularly interesting due to its unique genetic and metabolic capabilities. One of the most notable features of S. cardiffensis is its ability to produce a variety of secondary metabolites, which have potential applications in biotechnology and medicine. These metabolites can include antibiotics, enzymes, and other bioactive compounds that are valuable for pharmaceutical development and industrial processes. Another intriguing aspect of S. cardiffensis is its adaptation to specific ecological niches. This bacterium has been isolated from diverse environments, indicating its versatility and resilience. Its ability to thrive in different conditions makes it a subject of interest for studies on microbial ecology and environmental microbiology. From a research perspective, S. cardiffensis is also valuable for its genomic insights. The genome of this bacterium provides a wealth of information about the genetic basis of its metabolic pathways and ecological adaptations. Understanding these genetic factors can lead to the development of new biotechnological applications and enhance our knowledge of microbial diversity and evolution. In summary, Schaalia cardiffensis stands out due to its production of secondary metabolites, ecological versatility, and genomic insights, making it a valuable organism for scientific research and biotechnological innovation.

Schaalia cardiffensis is a fascinating bacterium that was first isolated from a clinical sample in Cardiff, Wales. This organism is particularly interesting due to its unique metabolic capabilities, which allow it to thrive in specific environments that are often inhospitable to other microorganisms. It has been shown to utilize a variety of carbon sources, making it a valuable subject for studies on microbial metabolism and adaptation. One of the most notable features of S. cardiffensis is its potential role in human health. Research has indicated that it may be involved in certain infections, providing insights into the complex interactions between human hosts and their microbiota. This aspect makes it a significant organism for understanding microbial pathogenesis and the development of new therapeutic strategies. Additionally, S. cardiffensis has garnered attention in the field of environmental microbiology. Its ability to survive in diverse ecological niches suggests that it may play a role in nutrient cycling and ecosystem dynamics. This characteristic opens avenues for research into its ecological impact and potential applications in bioremediation. Overall, Schaalia cardiffensis stands out as a microbe of interest not only for its clinical implications but also for its ecological significance, making it a valuable organism for ongoing research in both medical and environmental microbiology.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Actinomycetales

Family: Actinomycetaceae

Genus: Schaalia

Species: Schaalia cardiffensis

NCBI ID

181487

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/016/405/145/GCA_016405145.1_ASM1640514v1

File for sequence-based predictions:
GCA_016405145.1_ASM1640514v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The microorganism Schaalia cardiffensis is a Gram-negative bacterium that has been associated with various clinical implications, particularly in the context of infections in immunocompromised patients. It is known to be part of the normal flora of the human gastrointestinal tract, but it can become pathogenic under certain conditions. Clinical relevance includes its potential role in nosocomial infections, particularly in patients with underlying health issues or those undergoing invasive procedures. The organism has been implicated in cases of bacteremia and wound infections, highlighting its pathogenic potential. One of the significant concerns regarding Schaalia cardiffensis is its antimicrobial resistance. Reports indicate that this organism may exhibit resistance to multiple classes of antibiotics, complicating treatment options for infected patients. This resistance is often attributed to the acquisition of resistance genes and the ability to form biofilms, which enhance its survival in hostile environments, such as those found in hospital settings. In terms of immune evasion, Schaalia cardiffensis may employ various strategies to avoid detection and destruction by the host's immune system, although specific mechanisms are still under investigation. Its role in outbreaks is not well-documented, but its presence in clinical settings raises concerns about its potential to cause sporadic infections, particularly in vulnerable populations. Overall, while Schaalia cardiffensis is not as widely recognized as some other pathogens, its clinical implications warrant attention, especially in the context of antimicrobial stewardship and infection control measures in healthcare facilities.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Schaalia cardiffensis is a bacterium that is primarily associated with marine environments, particularly in areas with high organic matter. This microorganism thrives in coastal waters and is often found in sediments where it plays a crucial role in nutrient cycling. Its presence is indicative of healthy marine ecosystems, as it contributes to the breakdown of organic materials, thus facilitating the recycling of nutrients back into the food web. In these marine biomes, Schaalia cardiffensis engages in decomposition, breaking down complex organic compounds, which supports the growth of other microorganisms and higher trophic levels. This bacterium is also known to form symbiotic relationships with various marine organisms, aiding in their nutrient uptake and overall health. Furthermore, Schaalia cardiffensis exhibits remarkable environmental adaptability, allowing it to thrive in varying conditions such as changes in salinity and temperature. This adaptability is crucial for its survival in the dynamic coastal ecosystems where it is commonly found, making it an important player in maintaining the ecological balance of these habitats.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Schaalia cardiffensis has shown potential in various industrial applications, particularly in the fields of biotechnology and waste management. This organism is known for its ability to participate in biodegradation, where it can break down complex organic materials, making it valuable in the treatment of waste and the recycling of nutrients in ecosystems. In the realm of biofuel production, Schaalia cardiffensis can be utilized in fermentation processes to convert biomass into bioethanol, contributing to renewable energy sources. Its metabolic pathways allow for the efficient conversion of sugars derived from plant materials, which is crucial for sustainable energy solutions. Moreover, this microorganism has potential applications in pharmaceutical development due to its unique enzymatic activities. It can produce specific enzymes that may be harnessed for drug synthesis or as biocatalysts in various chemical reactions. The ability of Schaalia cardiffensis to thrive in diverse environments also makes it a candidate for bioremediation efforts, where it can help detoxify contaminated sites by breaking down pollutants. Overall, the versatility of Schaalia cardiffensis in fermentation, biodegradation, and enzyme production highlights its significance in advancing industrial processes and promoting environmental sustainability.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	google/palm-2-chat-bison-32k	google/gemini-flash-1.5	mistralai/mistral-7b-instruct	anthropic/claude-3.5-sonnet	meta-llama/llama-3-8b-instruct:nitro	meta-llama/llama-3-70b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	mistralai/mixtral-8x7b-instruct:nitro	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	google/gemini-pro-1.5	google/gemini-pro-1.5	openai/gpt-4	openai/gpt-4	anthropic/claude-3-haiku:beta	anthropic/claude-3-haiku:beta	google/gemini-pro	google/gemini-pro	openai/gpt-4o	openai/gpt-4o	google/gemma-7b-it	google/gemma-7b-it	openchat/openchat-7b	openchat/openchat-7b	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b
Motility	N/A	false	false	false	false	true	true	true	false	true	true	true	true	false	false	false	false	false	false	false	false	true	true	true	true	false	false	false	false
Gram staining	gram stain positive	gram stain negative ✗	gram stain negative ✗	gram stain variable ✗	gram stain positive ✓	gram stain negative ✗	gram stain positive ✓	gram stain negative ✗	gram stain negative ✗	N/A	gram stain negative ✗	N/A	gram stain negative ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain positive ✓
Aerophilicity	anaerobic	anaerobic ✓	N/A	aerotolerant ✗	N/A	N/A	N/A	N/A	N/A	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	N/A	N/A	anaerobic ✓	anaerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Biofilm formation	N/A	false	true	false	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false	true	true	true	true	true	true	false	false	true	true
Animal pathogenicity	FALSE	false ✓	true ✗	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗
Biosafety level	biosafety level 2	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓
Health association	N/A	false	true	false	true	true	true	true	false	false	false	true	true	true	true	true	true	false	false	true	true	true	true	false	false	false	false	true	true
Host association	FALSE	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	beta	N/A	gamma ✗	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	beta ✓	beta ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	N/A	bacillus	coccus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	coccus	coccus	bacillus	bacillus	bacillus	bacillus	coccus	coccus	bacillus	bacillus	bacillus	bacillus	coccus	coccus	coccus	coccus

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