Mycoplasmopsis fermentans

General Information

Mycoplasmopsis fermentans is a fascinating microorganism belonging to the class Mollicutes, which is characterized by the absence of a cell wall. This unique feature makes it inherently resistant to antibiotics that target cell wall synthesis, such as beta-lactams. One of the most intriguing aspects of M. fermentans is its small genome size, which is typical of mycoplasmas, allowing it to be a model organism for studying minimal cellular life and genome reduction. Mycoplasmopsis fermentans has been implicated in a variety of human diseases, including respiratory and urogenital infections, and has been studied for its potential role in chronic illnesses such as chronic fatigue syndrome and rheumatoid arthritis. This has made it a subject of interest in medical microbiology and immunology. Another notable characteristic of M. fermentans is its ability to evade the host immune system. It achieves this through antigenic variation, a process by which it alters its surface proteins to avoid detection. This makes it a challenging pathogen to study and control, but also provides valuable insights into host-pathogen interactions and immune evasion mechanisms. In addition to its medical relevance, M. fermentans is also studied for its metabolic capabilities. Despite its reduced genome, it retains a versatile metabolism that allows it to ferment a variety of substrates, which is reflected in its species name. This metabolic flexibility is of interest in the study of microbial ecology and evolution. Overall, Mycoplasmopsis fermentans is a microorganism of significant interest due to its unique biological features, its role in human disease, and its utility in scientific research on minimal genomes and host-pathogen interactions.

Mycoplasmopsis fermentans is a fascinating member of the Mycoplasmataceae family, notable for its unique characteristics and potential applications in research. This microorganism is particularly interesting due to its lack of a cell wall, which is a defining feature of the Mycoplasma genus. This absence of a rigid structure allows M. fermentans to exhibit a highly flexible morphology, enabling it to adapt to various environments and host organisms. One of the most significant aspects of M. fermentans is its ability to ferment a variety of carbohydrates, producing organic acids as metabolic byproducts. This metabolic versatility makes it a valuable model organism for studying fermentation processes and metabolic pathways in prokaryotes. Researchers are particularly interested in its role in the human microbiome, as it has been associated with various health conditions, including respiratory diseases and other infections. Furthermore, M. fermentans has been studied for its potential use in biotechnology, particularly in the production of biofuels and other bioproducts. Its unique metabolic capabilities could be harnessed to develop more efficient fermentation processes, contributing to sustainable energy solutions. In summary, Mycoplasmopsis fermentans stands out due to its flexible morphology, metabolic versatility, and potential applications in both health and biotechnology, making it a significant subject of study in microbiological research.

Taxonomy

Superkingdom: Bacteria

Phylum: Mycoplasmatota

Class: NA

Order: Mycoplasmoidales

Family: Metamycoplasmataceae

Genus: Mycoplasmopsis

Species: Mycoplasmopsis fermentans

NCBI ID

2115

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/900/660/535/GCA_900660535.1_50681_A01-3

File for sequence-based predictions:
GCA_900660535.1_50681_A01-3_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The microorganism Mycoplasmopsis fermentans is a member of the Mycoplasma genus, which is known for its unique characteristics and clinical implications. This organism has been associated with various infections and is particularly noted for its role in chronic diseases. It has been implicated in conditions such as chronic fatigue syndrome and fibromyalgia, where it may contribute to persistent symptoms through immune modulation and chronic inflammation. One of the significant concerns regarding Mycoplasmopsis fermentans is its potential for pathogenicity. It can evade the host's immune response through various mechanisms, including the alteration of surface proteins and the production of immunosuppressive factors. This ability to evade the immune system can lead to prolonged infections and complicate treatment strategies. In terms of antimicrobial resistance, Mycoplasmopsis fermentans exhibits resistance to many common antibiotics due to its lack of a cell wall, which makes it inherently resistant to beta-lactam antibiotics. This resistance poses challenges in clinical settings, as infections caused by this organism may not respond to standard treatment regimens. Additionally, there is ongoing research into the potential use of Mycoplasmopsis fermentans in medical applications, particularly in the development of probiotics or as a model organism for studying host-pathogen interactions. However, its clinical relevance remains a topic of investigation, and more studies are needed to fully understand its role in human health and disease.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Mycoplasmopsis fermentans is a type of bacterium that is primarily associated with the human microbiome, particularly in the respiratory tract and urogenital tract. This microorganism thrives in environments that are rich in organic material and can often be found in association with other microbial communities. Its presence is notable in the following biomes: Human Microbiome: - Mycoplasmopsis fermentans plays a significant role in maintaining the balance of the microbial ecosystem within the human body. It is involved in symbiotic relationships with host cells, contributing to the overall health of the microbiome by aiding in nutrient absorption and immune modulation. - This bacterium can also be involved in pathogenic interactions, particularly in immunocompromised individuals, where it may contribute to disease processes. Soil Microbiome: - In soil environments, Mycoplasmopsis fermentans can be found in nutrient-rich areas, where it participates in the decomposition of organic matter. This process is crucial for nutrient cycling and soil health. - The bacterium may engage in interactions with plants, potentially influencing plant health and growth through its metabolic activities. Overall, Mycoplasmopsis fermentans demonstrates a remarkable ability to adapt to various ecological niches, showcasing its importance in both human health and environmental ecosystems.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Mycoplasmopsis fermentans has shown potential in various industrial applications primarily due to its unique metabolic capabilities. One of the most notable areas is in biotechnology, where Mycoplasmopsis fermentans can be utilized in fermentation processes to produce valuable metabolites. This includes the production of organic acids and alcohols, which are essential in the food and beverage industry as well as in the manufacture of biofuels. In the realm of waste management, Mycoplasmopsis fermentans has been studied for its ability to degrade complex organic compounds, making it a candidate for biodegradation processes. This can be particularly useful in treating wastewater and reducing environmental pollutants, thereby contributing to more sustainable waste management practices. Furthermore, the organism's enzymatic activity can be harnessed in pharmaceutical development. The enzymes produced by Mycoplasmopsis fermentans may facilitate the synthesis of pharmaceutical compounds, enhancing the efficiency of drug production processes. Overall, the versatility of Mycoplasmopsis fermentans in these applications highlights its significance in advancing industrial biotechnology, promoting environmental sustainability, and supporting pharmaceutical innovation.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 8

LLM predicted phenotypes: 5

Phenotype	High-quality annotation	openai/gpt-3.5-turbo-0125	anthropic/claude-3.5-sonnet	meta-llama/llama-3-8b-instruct:nitro	google/gemini-flash-1.5	anthropic/claude-3-haiku:beta	google/gemma-7b-it	mistralai/mixtral-8x7b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	openchat/openchat-7b	google/gemini-pro-1.5	google/gemini-pro-1.5	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	meta-llama/llama-3-70b-instruct:nitro	meta-llama/llama-3-70b-instruct:nitro	openai/gpt-4o	openai/gpt-4o	openai/gpt-4	openai/gpt-4	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	mistralai/mistral-7b-instruct	mistralai/mistral-7b-instruct	google/gemini-pro	google/gemini-pro
Motility	N/A	false	false	false	false	true	true	false	true	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false
Gram staining	gram stain positive	gram stain negative ✗	gram stain negative ✗	gram stain negative ✗	gram stain negative ✗	gram stain negative ✗	gram stain negative ✗	gram stain negative ✗	gram stain negative ✗	gram stain negative ✗	N/A	gram stain negative ✗	N/A	gram stain negative ✗	N/A	gram stain negative ✗	N/A	gram stain variable ✗	N/A	gram stain negative ✗	N/A	gram stain negative ✗	N/A	gram stain negative ✗	N/A	gram stain variable ✗	N/A	gram stain negative ✗
Aerophilicity	facultatively anaerobic	facultatively anaerobic ✓	N/A	aerotolerant ✗	facultatively anaerobic ✓	N/A	N/A	facultatively anaerobic ✓	N/A	N/A	facultatively anaerobic ✓	facultatively anaerobic ✓	anaerobic ✗	anaerobic ✗	facultatively anaerobic ✓	facultatively anaerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Biofilm formation	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗
Animal pathogenicity	N/A	false	true	false	true	true	false	true	true	false	true	true	false	false	true	true	true	true	true	true	false	false	true	true	true	true	false	false
Biosafety level	biosafety level 2	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗
Health association	N/A	false	true	false	true	true	true	true	true	false	true	true	true	true	true	true	true	true	true	true	false	false	true	true	true	true	true	true
Host association	TRUE	false ✗	true ✓	false ✗	true ✓	true ✓	false ✗	true ✓	true ✓	false ✗	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	N/A	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false
Hemolysis	N/A	N/A	alpha	N/A	N/A	alpha	alpha	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	coccus	bacillus ✗	coccus ✓	coccus ✓	coccus ✓	bacillus ✗	bacillus ✗	coccus ✓	coccus ✓	coccus ✓	coccus ✓	coccus ✓	coccus ✓	coccus ✓	coccus ✓	coccus ✓	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	coccus ✓	coccus ✓	bacillus ✗	bacillus ✗	coccus ✓	coccus ✓	coccus ✓	coccus ✓

Back to Search