Streptomyces jietaisiensis

General Information

Streptomyces jietaisiensis is a fascinating microorganism belonging to the genus Streptomyces, which is renowned for its prolific production of secondary metabolites. One of the most notable characteristics of S. jietaisiensis is its ability to produce a wide array of bioactive compounds, including antibiotics, antifungals, and antitumor agents. This makes it a valuable organism in the field of natural product discovery and pharmaceutical research. Streptomyces species are well-known for their complex life cycle and filamentous growth, which resembles that of fungi. S. jietaisiensis forms a dense, branched mycelium and produces spores that are essential for its reproduction and dissemination. The organism's ability to thrive in diverse environments, including soil and decaying organic matter, underscores its ecological versatility and importance in nutrient cycling. From a biotechnological perspective, S. jietaisiensis is particularly interesting due to its genetic and metabolic diversity. The genome of S. jietaisiensis harbors numerous gene clusters responsible for the biosynthesis of secondary metabolites, many of which remain unexplored. This genetic potential offers exciting opportunities for the discovery of novel compounds with therapeutic applications. In addition to its pharmaceutical potential, S. jietaisiensis also plays a role in agriculture as a biocontrol agent. Its ability to produce antifungal and antibacterial compounds can help protect crops from pathogenic microorganisms, thereby reducing the reliance on chemical pesticides and promoting sustainable agricultural practices. Overall, Streptomyces jietaisiensis is a microorganism of significant interest due to its remarkable capacity to produce bioactive compounds, its ecological role, and its potential applications in medicine and agriculture. Continued research on this species is likely to yield valuable insights and innovations in various scientific fields.

Streptomyces jietaisiensis is a fascinating species of actinobacteria that was first isolated from soil samples in the Jietai Mountain region of China. This organism is particularly noteworthy due to its ability to produce a diverse array of bioactive compounds, which makes it a valuable resource in pharmaceutical research. The secondary metabolites derived from S. jietaisiensis have shown potential in antimicrobial, antifungal, and anticancer activities, highlighting its significance in the search for new therapeutic agents. One of the unique aspects of S. jietaisiensis is its genetic capacity for biosynthetic diversity. The genome of this species contains multiple gene clusters responsible for the synthesis of various natural products, which can be harnessed for drug discovery. Researchers are particularly interested in the potential of these compounds to combat antibiotic resistance, a growing concern in modern medicine. Additionally, S. jietaisiensis contributes to soil health and nutrient cycling, playing a crucial role in the ecosystem. Its ability to degrade complex organic materials makes it an important player in bioremediation efforts, where it can help in the breakdown of pollutants and restoration of contaminated environments. In summary, Streptomyces jietaisiensis stands out not only for its biotechnological potential but also for its ecological importance, making it a subject of ongoing research in both microbiology and environmental science.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Kitasatosporales

Family: Streptomycetaceae

Genus: Streptomyces

Species: Streptomyces jietaisiensis

NCBI ID

235987

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/900/102/095/GCA_900102095.1_IMG-taxon_2667527442_annotated_assembly

File for sequence-based predictions:
GCA_900102095.1_IMG-taxon_2667527442_annotated_assembly_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Streptomyces jietaisiensis is a member of the genus Streptomyces, which is known for its significant role in the production of antibiotics and other bioactive compounds. While specific clinical implications of Streptomyces jietaisiensis are not extensively documented, its relatives have been associated with various beneficial and pathogenic properties. Antibiotic production is one of the most notable aspects, as members of this genus are responsible for the synthesis of over two-thirds of naturally derived antibiotics, including streptomycin and tetracycline. This makes Streptomyces jietaisiensis potentially relevant in the development of new antimicrobial agents, especially in the context of rising antimicrobial resistance. In terms of human health, the genus Streptomyces is also involved in soil and environmental microbiomes, contributing to nutrient cycling and plant health. However, some species can be opportunistic pathogens, particularly in immunocompromised individuals. The pathogenicity of Streptomyces jietaisiensis itself has not been well characterized, but the genus is known for its ability to evade the immune response through various mechanisms, such as the production of enzymes that degrade host tissues and the ability to form biofilms. Furthermore, the potential use of Streptomyces jietaisiensis in probiotics or as a source of novel therapeutics is an area of interest, given the historical significance of the genus in medicine. Research into its metabolites may yield new insights into its role in human health and disease. Overall, while direct clinical implications of Streptomyces jietaisiensis remain to be fully elucidated, its association with antibiotic production and potential pathogenicity underscores its relevance in microbiology and medicine.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Streptomyces jietaisiensis is a species of actinobacteria that is primarily found in soil environments and is particularly associated with terrestrial biomes. This microorganism thrives in nutrient-rich soils, often in areas with high organic matter content, such as decaying plant material and leaf litter. Its presence is crucial in these ecosystems as it plays a significant role in the decomposition process, breaking down complex organic compounds and recycling nutrients back into the soil. In addition to its role in nutrient cycling, Streptomyces jietaisiensis is known for its ability to produce a variety of bioactive compounds, including antibiotics. This characteristic not only aids in its survival by inhibiting competing microorganisms but also contributes to the overall health of the soil microbiome. The interactions between Streptomyces jietaisiensis and other soil-dwelling organisms can be classified as competitive and mutualistic, where it may compete for resources or form beneficial relationships with plants through mycorrhizal associations. Furthermore, this microorganism exhibits remarkable environmental adaptability, allowing it to thrive in varying conditions, including changes in moisture and nutrient availability. Its resilience makes it a key player in maintaining the stability of ecosystem functions within its habitat. Overall, Streptomyces jietaisiensis exemplifies the intricate relationships and ecological roles that microorganisms play in terrestrial biomes.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Streptomyces jietaisiensis has shown significant potential in various industrial applications, particularly in the fields of biotechnology, pharmaceutical development, and waste management. This actinobacterium is known for its ability to produce a wide range of bioactive compounds, including antibiotics, which are crucial in the development of new pharmaceuticals. The fermentation processes employed by Streptomyces jietaisiensis allow for the extraction of these valuable metabolites, making it a key player in the pharmaceutical industry. In addition to its pharmaceutical applications, Streptomyces jietaisiensis is also involved in biodegradation processes, where it can break down complex organic materials, thus playing a vital role in waste treatment and environmental remediation. This capability is particularly important in the management of agricultural waste and the degradation of pollutants, contributing to sustainable waste management practices. Furthermore, the enzymatic activities of Streptomyces jietaisiensis can be harnessed for biofuel production, where it aids in the breakdown of lignocellulosic biomass, enhancing the efficiency of biofuel generation through enzymatic hydrolysis. Overall, Streptomyces jietaisiensis exemplifies the versatility of microorganisms in addressing industrial challenges, particularly in the realms of biotechnology and environmental sustainability.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	anthropic/claude-3.5-sonnet	google/gemini-flash-1.5	google/gemini-flash-1.5	meta-llama/llama-3-70b-instruct:nitro	google/gemini-pro	meta-llama/llama-3-8b-instruct:nitro	anthropic/claude-3-haiku:beta	google/gemma-7b-it	microsoft/phi-3-mini-128k-instruct	mistralai/mistral-7b-instruct	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	perplexity/llama-3-sonar-small-32k-chat	perplexity/llama-3-sonar-small-32k-chat	openchat/openchat-7b	openchat/openchat-7b	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mixtral-8x7b-instruct:nitro
Motility	N/A	false	false	false	false	false	false	false	true	true	false	false	false	false	false	false	false	false	false	false	false	false	false	true	true	false	false	false	false
Gram staining	gram stain positive	gram stain positive ✓	N/A	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	true ✗	true ✗	true ✗	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗
Biofilm formation	N/A	true	true	true	true	true	true	true	true	true	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false	true	true
Animal pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 3 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	true	false	false	true	true	false	true	true	false	false	false	false	true	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true
Host association	FALSE	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Spore formation	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Hemolysis	N/A	N/A	gamma	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	tail	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	spirillum ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗

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