Prevotella veroralis

General Information

Prevotella veroralis is a fascinating microorganism primarily due to its role in the human oral microbiome. This bacterium is part of the genus Prevotella, which is known for its diverse metabolic capabilities and its involvement in various human health conditions. One of the most interesting aspects of P. veroralis is its association with periodontal disease, a common inflammatory condition affecting the tissues surrounding the teeth. P. veroralis is also notable for its ability to degrade complex carbohydrates, which is a characteristic feature of many Prevotella species. This metabolic versatility allows it to thrive in the nutrient-rich environment of the human mouth, where it contributes to the breakdown of dietary polysaccharides. From a research perspective, P. veroralis is valuable for studying the dynamics of the oral microbiome and its impact on oral and systemic health. Its presence in the oral cavity has been linked to both health and disease states, making it a key organism for understanding the balance between beneficial and pathogenic microbial communities. Moreover, Prevotella species, including P. veroralis, are of interest due to their potential role in the gut-brain axis and their influence on systemic inflammation. This opens up avenues for research into how oral health might impact overall health, including conditions such as cardiovascular disease and diabetes. In summary, Prevotella veroralis is a microorganism of significant interest due to its metabolic capabilities, its role in oral health and disease, and its potential implications for systemic health. Its study can provide insights into the complex interactions within the human microbiome and their broader health impacts.

Prevotella veroralis is a fascinating member of the Prevotella genus, which is known for its role in the human microbiome, particularly in the oral cavity and gastrointestinal tract. This species has garnered attention due to its unique metabolic capabilities and its potential implications in human health and disease. One of the most interesting aspects of Prevotella veroralis is its ability to metabolize a variety of carbohydrates, including complex polysaccharides, which allows it to thrive in diverse environments. Ecological Role: Prevotella veroralis plays a significant role in the degradation of dietary fibers, contributing to the overall health of the gut microbiome. Its metabolic processes can influence the production of short-chain fatty acids (SCFAs), which are crucial for maintaining gut health and modulating immune responses. Research Significance: The study of Prevotella veroralis is particularly valuable in understanding the dynamics of the oral and gut microbiota. Research has indicated that variations in the abundance of Prevotella species, including P. veroralis, may be associated with various health conditions, such as periodontal disease and inflammatory bowel disease. This makes it a potential biomarker for these conditions, providing insights into microbial dysbiosis. Genomic Insights: Recent genomic studies have revealed that Prevotella veroralis possesses unique genetic traits that enable it to adapt to different environments within the human body. The presence of specific genes related to carbohydrate metabolism and antibiotic resistance highlights its potential role in both health and disease. Understanding these genetic factors can aid in the development of targeted therapies and probiotics aimed at restoring a healthy microbiome. In summary, Prevotella veroralis is a unique and valuable organism in microbiome research, with implications for human health, disease understanding, and potential therapeutic applications.

Taxonomy

Superkingdom: Bacteria

Phylum: Bacteroidota

Class: Bacteroidia

Order: Bacteroidales

Family: Prevotellaceae

Genus: Prevotella

Species: Prevotella veroralis

NCBI ID

28137

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/018/127/765/GCA_018127765.1_ASM1812776v1

File for sequence-based predictions:
GCA_018127765.1_ASM1812776v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The microorganism Prevotella veroralis is a member of the genus Prevotella, which is known for its role in the human microbiome, particularly in the oral and gastrointestinal tracts. This organism has been associated with various clinical implications, particularly in relation to oral health and periodontal disease. It is often found in the subgingival plaque of individuals with periodontitis, indicating its potential role as a pathogen in this condition. Furthermore, Prevotella veroralis has been implicated in systemic infections and has been isolated from cases of bacteremia, highlighting its ability to enter the bloodstream and cause serious health issues. In terms of antimicrobial resistance, members of the Prevotella genus, including Prevotella veroralis, have shown resistance to multiple classes of antibiotics, which complicates treatment options for infections associated with this organism. This resistance is often attributed to the production of beta-lactamases and other mechanisms that allow the bacteria to survive in the presence of antimicrobial agents. Additionally, the role of Prevotella veroralis in the human microbiome suggests potential medical applications, particularly in the development of probiotics aimed at restoring a healthy balance of oral and gut microbiota. Understanding the interactions of Prevotella veroralis with the human immune system is crucial, as it may employ various immune evasion strategies to persist in host tissues, contributing to chronic inflammatory conditions. Overall, the clinical relevance of Prevotella veroralis underscores the importance of further research into its pathogenic mechanisms, resistance profiles, and potential therapeutic applications.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Prevotella veroralis is a species of bacteria commonly found in the oral cavity of humans and other mammals. This microorganism thrives in the complex and dynamic environment of the oral microbiome, where it plays a significant role in maintaining the balance of microbial communities. The oral cavity serves as a unique habitat characterized by varying pH levels, moisture, and nutrient availability, which are influenced by dietary habits and oral hygiene practices. In the oral biome, Prevotella veroralis is known to engage in symbiotic relationships with other microbial species, contributing to the overall health of the oral ecosystem. It participates in the breakdown of complex carbohydrates and proteins, aiding in the digestion process and influencing the availability of nutrients for other microorganisms. This bacterium can also produce metabolites that may inhibit the growth of pathogenic bacteria, thus playing a protective role in the oral environment. Furthermore, Prevotella veroralis is associated with various oral health conditions, including periodontal disease. Its presence can indicate shifts in the microbial community that may lead to dysbiosis, highlighting its importance in the ecological balance of the oral cavity. The adaptability of Prevotella veroralis to different conditions within the oral biome underscores its role as a key player in the intricate web of interactions that define this habitat.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Prevotella veroralis has shown potential in various industrial applications, particularly in the fields of biotechnology and waste management. This organism is known for its role in fermentation, where it can contribute to the breakdown of complex carbohydrates, making it valuable in the production of biofuels. By utilizing its metabolic pathways, Prevotella veroralis can help convert biomass into fermentable sugars, which can then be transformed into ethanol or other biofuels, thus supporting sustainable energy initiatives. In the realm of waste management, Prevotella veroralis is involved in biodegradation processes, particularly in the degradation of organic waste materials. Its ability to break down proteins and polysaccharides can enhance composting processes, leading to more efficient waste treatment and nutrient recycling. This is particularly important in agricultural settings where organic waste needs to be managed effectively. Furthermore, there is emerging interest in the pharmaceutical development sector, where Prevotella veroralis may play a role in the production of bioactive compounds. Its enzymatic activity could be harnessed to produce specific metabolites that have therapeutic potential, although this area is still under investigation. Overall, Prevotella veroralis demonstrates significant promise in enhancing processes related to biofuel production, waste treatment, and potentially in the development of pharmaceuticals, making it a noteworthy organism in industrial biotechnology.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 8

LLM predicted phenotypes: 5

Phenotype	High-quality annotation	google/gemini-pro-1.5	anthropic/claude-3.5-sonnet	google/gemini-flash-1.5	anthropic/claude-3-haiku:beta	meta-llama/llama-3-70b-instruct:nitro	mistralai/mistral-7b-instruct	perplexity/llama-3-sonar-small-32k-chat	google/gemma-7b-it	google/gemini-pro	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	meta-llama/llama-3-8b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	openai/gpt-4	openai/gpt-4	openchat/openchat-7b	openchat/openchat-7b	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mixtral-8x7b-instruct:nitro
Motility	N/A	false	false	false	true	false	true	true	true	true	true	true	false	false	true	true	false	false	false	false	false	false	true	true	false	false	false	false
Gram staining	gram stain negative	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓
Aerophilicity	anaerobic	anaerobic ✓	anaerobic ✓	N/A	N/A	anaerobic ✓	aerotolerant ✗	N/A	N/A	N/A	facultatively anaerobic ✗	facultatively anaerobic ✗	anaerobic ✓	anaerobic ✓	aerotolerant ✗	aerotolerant ✗	anaerobic ✓	anaerobic ✓	anaerobic ✓	anaerobic ✓	anaerobic ✓	anaerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Biofilm formation	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	N/A	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true	true	true	false	false	true	true	true	true	false	false	false	false
Biosafety level	biosafety level 1	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Host association	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	N/A	N/A	N/A	gamma	alpha	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	bacillus ✓	bacillus ✓

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