Acinetobacter junii

General Information

Acinetobacter junii is a species of bacteria that has garnered attention due to its clinical significance and environmental adaptability. This microorganism is part of the Acinetobacter genus, which is known for its ability to survive in a variety of environments, including soil, water, and hospital settings. One of the most intriguing aspects of A. junii is its association with nosocomial infections, particularly in immunocompromised patients. It has been isolated from various clinical specimens, including blood, urine, and respiratory secretions, indicating its potential to cause a range of infections. From a research perspective, A. junii is valuable due to its antibiotic resistance mechanisms. Studies have shown that this bacterium can harbor multiple resistance genes, making it a model organism for understanding the genetic basis of antibiotic resistance. This is particularly important in the context of the growing global issue of multidrug-resistant bacterial infections. Another unique characteristic of A. junii is its metabolic versatility. It can utilize a wide range of organic compounds as carbon sources, which contributes to its survival in diverse environments. This metabolic flexibility is of interest to researchers studying microbial ecology and bioremediation, as A. junii has the potential to degrade environmental pollutants. In summary, Acinetobacter junii is a microorganism of significant interest due to its clinical relevance, antibiotic resistance, and metabolic capabilities. Its study not only enhances our understanding of bacterial pathogenesis and resistance but also offers insights into potential applications in environmental science.

Acinetobacter junii is a notable member of the Acinetobacter genus, which is recognized for its environmental versatility and ability to thrive in various habitats, including soil and water. This organism is particularly interesting due to its emerging role in clinical settings, where it has been associated with opportunistic infections, especially in immunocompromised patients. Its resilience to antibiotics makes it a subject of significant research interest, as scientists seek to understand the mechanisms behind its resistance and explore potential therapeutic strategies. One of the unique aspects of A. junii is its genetic adaptability, which allows it to acquire resistance genes from other bacteria. This characteristic not only complicates treatment options but also raises concerns about its potential to contribute to the spread of antibiotic resistance in healthcare environments. Furthermore, A. junii has been studied for its bioremediation potential, as it can degrade various pollutants, making it valuable in environmental microbiology. In addition to its clinical implications, the organism's metabolic diversity allows it to utilize a wide range of carbon sources, which is of interest in studies related to microbial ecology and biotechnology. Overall, Acinetobacter junii serves as a critical model for understanding both the challenges posed by antibiotic-resistant pathogens and the potential applications of bacteria in environmental cleanup efforts.

Taxonomy

Superkingdom: Bacteria

Phylum: Pseudomonadota

Class: Gammaproteobacteria

Order: Moraxellales

Family: Moraxellaceae

Genus: Acinetobacter

Species: Acinetobacter junii

NCBI ID

40215

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/018/336/855/GCA_018336855.1_ASM1833685v1

File for sequence-based predictions:
GCA_018336855.1_ASM1833685v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Acinetobacter junii is a member of the Acinetobacter genus, which is known for its clinical significance, particularly in hospital settings. It is associated with a variety of infections, including pneumonia, bloodstream infections, and wound infections. Acinetobacter junii is often implicated in infections among immunocompromised patients, making it a notable pathogen in healthcare-associated infections. One of the critical aspects of Acinetobacter junii is its antimicrobial resistance. This organism has shown resistance to multiple classes of antibiotics, including beta-lactams, aminoglycosides, and fluoroquinolones. The presence of resistance mechanisms, such as the production of beta-lactamases and efflux pumps, complicates treatment options and poses a significant challenge in clinical management. In terms of immune evasion, Acinetobacter junii can alter its surface structures and produce biofilms, which protect it from both the host immune response and antibiotic treatment. This ability to form biofilms is particularly concerning in the context of medical devices, where it can lead to persistent infections. While Acinetobacter junii is not as widely studied as other members of the Acinetobacter genus, its role in nosocomial outbreaks highlights the need for ongoing surveillance and research. Understanding its pathogenic mechanisms and resistance profiles is crucial for developing effective treatment strategies and infection control measures in healthcare settings.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Acinetobacter junii is a versatile bacterium commonly found in a variety of habitats and environments, particularly in urban and agricultural settings. This microorganism thrives in soil and water ecosystems, often associated with human activity and organic matter decomposition. Its adaptability allows it to survive in both aerobic and anaerobic conditions, making it a resilient inhabitant of diverse ecological niches. In urban environments, Acinetobacter junii is frequently isolated from hospital settings, where it can be part of the microbial flora on surfaces and medical equipment. This bacterium plays a significant role in the microbial community, contributing to the breakdown of organic materials and influencing nutrient cycling. In agricultural contexts, Acinetobacter junii can be found in soil enriched with fertilizers and organic amendments. Here, it participates in symbiotic relationships with plants, potentially enhancing nutrient availability and promoting plant health. Its ability to degrade various compounds also positions it as a candidate for bioremediation efforts in contaminated soils. Overall, Acinetobacter junii exemplifies the adaptability of microorganisms to thrive in human-altered environments, showcasing its importance in both ecological balance and potential applications in environmental management.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Acinetobacter junii has shown significant potential in various industrial applications. One of the primary areas of interest is in biotechnology, where Acinetobacter junii is utilized for its ability to degrade a wide range of pollutants, making it valuable in biodegradation processes. This capability allows it to be employed in waste management, particularly in the treatment of contaminated water and soil, where it can break down harmful substances such as hydrocarbons and heavy metals. In the realm of biofuel production, Acinetobacter junii has been studied for its capacity to produce lipids that can be converted into biodiesel. The organism's metabolic pathways can be harnessed in fermentation processes to enhance lipid accumulation, thus contributing to sustainable energy solutions. Furthermore, Acinetobacter junii has potential applications in pharmaceutical development. Its unique enzymatic activities can be explored for the production of bioactive compounds, which may lead to the discovery of new drugs or therapeutic agents. The organism's ability to produce various enzymes can also be utilized in enzyme production, which is crucial for numerous industrial processes, including food processing and biocatalysis. Overall, Acinetobacter junii represents a versatile microorganism with promising applications across multiple industries, particularly in environmental biotechnology, renewable energy, and healthcare.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 8

LLM predicted phenotypes: 5

Phenotype	High-quality annotation	anthropic/claude-3.5-sonnet	meta-llama/llama-3-8b-instruct:nitro	anthropic/claude-3-haiku:beta	meta-llama/llama-3-70b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	google/gemma-7b-it	microsoft/phi-3-mini-128k-instruct	mistralai/mixtral-8x7b-instruct:nitro	google/gemini-pro	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	openai/gpt-4	openai/gpt-4	google/gemini-flash-1.5	google/gemini-flash-1.5	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	openchat/openchat-7b	openchat/openchat-7b	mistralai/mistral-7b-instruct	mistralai/mistral-7b-instruct
Motility	N/A	false	true	true	true	true	true	false	false	true	false	false	false	false	false	false	false	false	false	false	false	false	true	true	false	false	false	false
Gram staining	gram stain negative	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓
Aerophilicity	aerobic	aerobic ✓	aerotolerant ✗	N/A	N/A	N/A	N/A	N/A	N/A	N/A	facultatively anaerobic ✗	facultatively anaerobic ✗	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	false ✓	false ✓	true ✗	true ✗	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗
Biofilm formation	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false	true	true
Animal pathogenicity	N/A	true	true	true	true	true	true	false	false	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true	false	false	false	false
Biosafety level	biosafety level 2	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗
Health association	N/A	true	true	true	true	true	true	false	true	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true	false	false	false	false
Host association	FALSE	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	N/A	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	gamma	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	coccus ✗	coccus ✗	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	bacillus ✓	bacillus ✓

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