Acinetobacter radioresistens

General Information

Acinetobacter radioresistens is a fascinating microorganism primarily due to its remarkable resistance to ionizing radiation. This characteristic makes it an organism of significant interest in the field of astrobiology and radiobiology. The ability to withstand high levels of radiation suggests potential applications in bioremediation, particularly in environments contaminated with radioactive materials. Another intriguing aspect of A. radioresistens is its capacity for horizontal gene transfer, which allows it to acquire and disseminate antibiotic resistance genes. This trait is particularly concerning in clinical settings, as it can contribute to the spread of multidrug-resistant infections. Moreover, A. radioresistens has been studied for its metabolic versatility. It can utilize a wide range of substrates for growth, which makes it a model organism for studying microbial adaptation and survival in extreme conditions. In summary, Acinetobacter radioresistens stands out due to its radiation resistance, antibiotic resistance gene transfer, and metabolic adaptability, making it a valuable subject for research in multiple scientific disciplines.

Acinetobacter radioresistens is a remarkable bacterium known for its extraordinary resilience to ionizing radiation. This unique characteristic makes it a subject of interest in various fields, particularly in astrobiology and bioremediation. The ability of A. radioresistens to withstand high doses of radiation is attributed to its efficient DNA repair mechanisms, which allow it to survive in extreme environments where other microorganisms would perish. This resilience not only highlights the adaptability of life but also raises questions about the potential for life in extraterrestrial environments. In addition to its radiation resistance, A. radioresistens has been studied for its potential applications in bioremediation, particularly in the degradation of pollutants. Its metabolic versatility enables it to utilize a range of organic compounds, making it a candidate for the bioremediation of contaminated sites. The bacterium's ability to thrive in harsh conditions could be harnessed to develop innovative strategies for environmental cleanup. Furthermore, A. radioresistens has garnered attention in the field of microbiology due to its genetic and biochemical properties. Researchers are investigating its genome to understand the underlying mechanisms of its radiation resistance and metabolic capabilities. This research could lead to advancements in genetic engineering and synthetic biology, potentially paving the way for the development of new biotechnological applications. Overall, Acinetobacter radioresistens stands out as a fascinating organism that not only challenges our understanding of microbial life but also offers promising avenues for scientific exploration and practical applications.

Taxonomy

Superkingdom: Bacteria

Phylum: Pseudomonadota

Class: Gammaproteobacteria

Order: Moraxellales

Family: Moraxellaceae

Genus: Acinetobacter

Species: Acinetobacter radioresistens

NCBI ID

40216

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCF/003/258/335/GCF_003258335.1_ASM325833v1

File for sequence-based predictions:
GCF_003258335.1_ASM325833v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Acinetobacter radioresistens is a gram-negative bacterium that has garnered attention due to its clinical implications in human health. It is primarily associated with nosocomial infections, particularly in immunocompromised patients, and can lead to serious conditions such as pneumonia, sepsis, and wound infections. This organism is known for its pathogenicity, often found in hospital settings where it can survive on surfaces and medical equipment, contributing to its role in outbreaks of infection. One of the significant concerns regarding Acinetobacter radioresistens is its antimicrobial resistance. It exhibits resistance to multiple classes of antibiotics, including beta-lactams and aminoglycosides, which complicates treatment options for infected patients. The mechanisms of resistance include the production of beta-lactamases and alterations in membrane permeability, which allow it to evade the effects of many commonly used antibiotics. In terms of immune evasion, Acinetobacter radioresistens can form biofilms, which protect it from both the host immune response and antibiotic treatment. This ability to adhere to surfaces and form protective layers is a significant factor in its pathogenicity and persistence in clinical environments. While Acinetobacter radioresistens is primarily recognized for its role in infections, there is ongoing research into its potential applications in biotechnology and medicine, particularly in the development of probiotics or as a model organism for studying antibiotic resistance mechanisms. However, its clinical relevance remains predominantly associated with its role as a pathogen in healthcare settings, necessitating continued surveillance and research to manage its impact on public health.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Acinetobacter radioresistens is a bacterium commonly found in a variety of habitats that are often characterized by their resilience to extreme conditions. This microorganism is particularly notable for its presence in soil and water environments, where it can thrive in both natural and anthropogenic settings. Its ability to withstand high levels of radiation and desiccation allows it to occupy niches that are inhospitable to many other organisms. Soil Biomes: In terrestrial ecosystems, Acinetobacter radioresistens is frequently isolated from contaminated soils, especially those impacted by human activities such as agriculture and industrial waste. Here, it plays a crucial role in the degradation of organic pollutants, contributing to nutrient cycling and soil health. Its metabolic versatility enables it to utilize a wide range of substrates, making it an important player in the microbial community. Aquatic Environments: This bacterium is also found in freshwater and marine ecosystems, where it can be associated with biofilms on surfaces or suspended in the water column. In these environments, Acinetobacter radioresistens can interact with other microorganisms, forming complex communities that enhance nutrient availability and energy flow. Its presence in these biomes is indicative of the microbial resilience and adaptability to varying environmental conditions. In addition to its ecological roles, Acinetobacter radioresistens has garnered attention for its potential in bioremediation efforts, particularly in environments contaminated with heavy metals and radioactive materials. Its unique adaptations not only allow it to survive but also to contribute positively to the ecosystem by breaking down harmful substances, thus highlighting its importance in maintaining ecological balance and promoting environmental health.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Acinetobacter radioresistens has shown significant potential in various industrial applications. One of the most notable areas is in biotechnology, where it is utilized for its ability to withstand high levels of radiation and its metabolic versatility. This resilience makes it a candidate for bioremediation, particularly in environments contaminated with radioactive materials or heavy metals, where it can help in the detoxification process. In the realm of waste management, Acinetobacter radioresistens has been studied for its capacity to degrade pollutants, including hydrocarbons and other organic compounds. This capability is crucial in biodegradation processes, where the organism can be employed to clean up oil spills or industrial waste, effectively reducing environmental impact. Furthermore, this microorganism has potential applications in biofuel production. Its metabolic pathways can be harnessed to convert waste materials into biofuels through fermentation processes, thereby contributing to sustainable energy solutions. In pharmaceutical development, Acinetobacter radioresistens is of interest due to its ability to produce various enzymes that can be used in drug formulation and synthesis. The enzymatic activity of this organism can facilitate the production of bioactive compounds, which are essential in the development of new therapeutic agents. Overall, Acinetobacter radioresistens demonstrates a multifaceted role in industrial biotechnology, particularly in bioremediation, waste treatment, and biofuel production, making it a valuable organism for future research and application in these fields.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	google/gemini-flash-1.5	mistralai/mixtral-8x7b-instruct:nitro	anthropic/claude-3-haiku:beta	meta-llama/llama-3-70b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	google/gemma-7b-it	openchat/openchat-7b	google/gemini-pro	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	google/gemini-pro-1.5	google/gemini-pro-1.5	anthropic/claude-3.5-sonnet	anthropic/claude-3.5-sonnet	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	openai/gpt-4o	openai/gpt-4o	meta-llama/llama-3-8b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	mistralai/mistral-7b-instruct	mistralai/mistral-7b-instruct
Motility	N/A	false	false	true	true	true	true	true	true	false	false	true	true	false	false	false	false	false	false	false	false	true	true	true	true	false	false	true	true
Gram staining	gram stain negative	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓
Aerophilicity	aerobic	N/A	facultatively anaerobic ✗	N/A	N/A	N/A	N/A	N/A	N/A	facultatively anaerobic ✗	facultatively anaerobic ✗	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗
Biofilm formation	FALSE	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗
Animal pathogenicity	FALSE	true ✗	false ✓	true ✗	false ✓	true ✗	true ✗	false ✓	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓
Biosafety level	biosafety level 1	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗
Health association	N/A	true	true	true	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false	true	true
Host association	N/A	true	true	true	true	true	false	true	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false	true	true
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	N/A	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	coccus ✗	coccus ✗	bacillus ✓	bacillus ✓	coccus ✗	bacillus ✓	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓

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