Pseudomonas alcaligenes

General Information

Pseudomonas alcaligenes is a fascinating microorganism known for its metabolic versatility and biotechnological potential. This bacterium is often found in soil and water environments, where it plays a crucial role in the degradation of various organic compounds. One of the most remarkable features of P. alcaligenes is its ability to degrade a wide range of pollutants, including aromatic hydrocarbons and other complex organic molecules, making it a valuable agent in bioremediation efforts. Another interesting aspect of Pseudomonas alcaligenes is its production of biosurfactants, which are surface-active substances that can reduce surface and interfacial tension. These biosurfactants have applications in environmental cleanup, particularly in the treatment of oil spills, and in various industrial processes. From a research perspective, P. alcaligenes is also notable for its genetic adaptability. It possesses a diverse set of genes that allow it to survive and thrive in different environmental conditions. This genetic flexibility makes it an excellent model organism for studying microbial adaptation and evolution. Moreover, Pseudomonas alcaligenes has been explored for its potential in biocontrol. It can inhibit the growth of certain plant pathogens, thereby promoting plant health and growth. This characteristic is particularly valuable in sustainable agriculture, where reducing the reliance on chemical pesticides is a significant goal. In summary, Pseudomonas alcaligenes stands out due to its environmental resilience, bioremediation capabilities, and biotechnological applications, making it a subject of considerable interest in both environmental and industrial microbiology.*

Pseudomonas alcaligenes is a fascinating bacterium known for its remarkable metabolic versatility and ability to thrive in diverse environments. This species is particularly interesting due to its capacity to degrade a wide range of organic compounds, including various pollutants, making it a valuable organism in bioremediation efforts. Its ability to utilize hydrocarbons and other toxic substances positions P. alcaligenes as a potential candidate for environmental cleanup applications, especially in contaminated soil and water systems. One of the unique features of Pseudomonas alcaligenes is its ability to produce a variety of enzymes that facilitate the breakdown of complex organic molecules. This enzymatic activity not only aids in bioremediation but also has implications for industrial biotechnology, where these enzymes can be harnessed for the production of biofuels and other valuable chemicals. Additionally, P. alcaligenes is known for its ability to grow in alkaline conditions, which is relatively uncommon among bacteria. This characteristic allows it to inhabit environments that are inhospitable to many other microorganisms, further highlighting its ecological significance. Moreover, research into Pseudomonas alcaligenes has revealed its potential in the field of synthetic biology. Scientists are exploring its genetic makeup to engineer strains that can enhance its metabolic capabilities, leading to improved efficiency in bioremediation and bioprocessing applications. The organism's adaptability and resilience make it a subject of ongoing research, with the potential to contribute significantly to environmental sustainability and industrial innovation.

Taxonomy

Superkingdom: Bacteria

Phylum: Pseudomonadota

Class: Gammaproteobacteria

Order: Pseudomonadales

Family: Pseudomonadaceae

Genus: Pseudomonas

Species: Pseudomonas alcaligenes

NCBI ID

43263

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCF/001/597/285/GCF_001597285.1_ASM159728v1

File for sequence-based predictions:
GCF_001597285.1_ASM159728v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Pseudomonas alcaligenes is a Gram-negative bacterium that is part of the natural flora of soil and water. It has been associated with various clinical implications, particularly in immunocompromised patients. Infections caused by Pseudomonas alcaligenes can occur, especially in individuals with underlying health conditions, such as cystic fibrosis or those undergoing invasive procedures. These infections can manifest as pneumonia, bacteremia, and wound infections, highlighting its potential pathogenicity in vulnerable populations. One of the notable features of Pseudomonas alcaligenes is its ability to exhibit antimicrobial resistance. This organism can develop resistance to multiple classes of antibiotics, complicating treatment options. The mechanisms of resistance include the production of beta-lactamases and the ability to form biofilms, which protect the bacteria from both the host immune response and antibiotic action. In terms of immune evasion, Pseudomonas alcaligenes can alter its surface structures and produce various virulence factors that help it evade detection and destruction by the host's immune system. This ability to adapt and survive in hostile environments contributes to its role as an opportunistic pathogen. While Pseudomonas alcaligenes is not commonly associated with outbreaks, its presence in clinical settings, particularly in patients with compromised immune systems, necessitates careful monitoring and management. Additionally, some strains of Pseudomonas alcaligenes have been explored for their potential use in bioremediation and as probiotics, although these applications are still under investigation and not widely implemented in clinical practice.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Pseudomonas alcaligenes is a versatile bacterium commonly found in a variety of habitat types and environments. This microorganism thrives in soil, water, and plant-associated environments, showcasing its adaptability to different ecological niches. It is particularly prevalent in alkaline soils and freshwater ecosystems, where it plays a significant role in nutrient cycling and organic matter decomposition. In soil ecosystems, Pseudomonas alcaligenes contributes to the breakdown of organic compounds, enhancing soil fertility and promoting plant growth. Its ability to degrade a wide range of pollutants, including hydrocarbons, makes it an important player in bioremediation efforts, helping to restore contaminated environments. In aquatic environments, this bacterium can be found in both freshwater and marine ecosystems, where it participates in the cycling of nutrients and can influence the microbial community structure. Its presence in biofilms on surfaces in these environments allows it to interact with other microorganisms, often leading to symbiotic relationships that can enhance nutrient availability. Additionally, Pseudomonas alcaligenes is known for its ability to form biofilms on plant roots, which can promote plant health through enhanced nutrient uptake and protection against pathogens. This plant-microbe interaction is crucial for maintaining the health of various ecosystems, particularly in agricultural settings. Overall, Pseudomonas alcaligenes exemplifies the intricate relationships within biomes, demonstrating its ecological significance through its diverse roles in nutrient cycling, pollution degradation, and plant health enhancement.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Pseudomonas alcaligenes has demonstrated significant potential in various industrial applications. One of the primary areas is in biotechnology, where it is utilized for its ability to perform biodegradation of environmental pollutants. This organism can break down complex organic compounds, making it valuable in waste management processes, particularly in the treatment of wastewater contaminated with hydrocarbons and other toxic substances. In the realm of biofuel production, Pseudomonas alcaligenes has been studied for its capacity to convert waste materials into biofuels through fermentation processes. This conversion not only helps in waste reduction but also contributes to sustainable energy solutions. Additionally, Pseudomonas alcaligenes is known for its pharmaceutical development applications, particularly in the production of enzymes that can be used in various biochemical reactions. The organism's enzymatic activity is harnessed in the synthesis of pharmaceuticals, where it can facilitate the production of specific compounds through enzyme production. Overall, Pseudomonas alcaligenes serves as a versatile microorganism with applications spanning from environmental remediation to energy production and pharmaceutical manufacturing, showcasing its importance in modern industrial processes.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 8

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	google/gemini-pro-1.5	anthropic/claude-3.5-sonnet	meta-llama/llama-3-8b-instruct:nitro	anthropic/claude-3-haiku:beta	meta-llama/llama-3-70b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	mistralai/mistral-7b-instruct	google/gemini-pro	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	google/gemini-flash-1.5	google/gemini-flash-1.5	google/gemma-7b-it	google/gemma-7b-it	openchat/openchat-7b	openchat/openchat-7b	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mixtral-8x7b-instruct:nitro
Motility	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Gram staining	gram stain negative	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	false ✓	true ✗	true ✗	true ✗	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗
Biofilm formation	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	TRUE	true ✓	false ✗	false ✗	true ✓	false ✗	true ✓	false ✗	true ✓	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗
Biosafety level	biosafety level 2	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗
Health association	N/A	true	true	true	true	true	true	false	true	false	false	false	false	true	true	true	true	false	false	true	true	true	true	false	false	false	false	true	true
Host association	N/A	true	true	true	true	true	true	true	true	false	false	false	false	false	false	true	true	false	false	true	true	true	true	true	true	true	true	true	true
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓

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