Pseudomonas chlororaphis

General Information

Pseudomonas chlororaphis is a fascinating microorganism known for its biocontrol properties and production of secondary metabolites. This bacterium is particularly interesting due to its ability to produce a variety of pigments, including phenazine compounds, which have antimicrobial properties. These phenazines not only give P. chlororaphis its characteristic greenish color but also play a crucial role in its ability to suppress plant pathogens, making it valuable in agricultural settings for the biological control of diseases. Another unique feature of Pseudomonas chlororaphis is its capacity to produce biosurfactants. These surface-active substances can reduce surface tension and have applications in bioremediation, where they help in the breakdown and removal of pollutants from the environment. The production of biosurfactants also contributes to the bacterium's ability to colonize plant roots and form beneficial associations with plants. From a research perspective, Pseudomonas chlororaphis is valuable due to its genetic tractability. Scientists can easily manipulate its genome, making it an excellent model organism for studying gene function and regulation. Additionally, its ability to produce a wide range of bioactive compounds has potential applications in biotechnology and pharmaceuticals. Overall, Pseudomonas chlororaphis stands out due to its biocontrol capabilities, production of valuable secondary metabolites, and potential applications in environmental and industrial biotechnology.

Pseudomonas chlororaphis is a fascinating bacterium known for its remarkable ability to produce a variety of bioactive compounds, particularly antibiotics and antifungal agents. This species is often found in soil and plant rhizospheres, where it plays a crucial role in promoting plant health and growth. One of its most notable characteristics is its production of chlororaphin, a compound that exhibits significant antimicrobial activity against various pathogens, making it a valuable candidate for agricultural applications and biocontrol strategies. In addition to its antimicrobial properties, Pseudomonas chlororaphis is recognized for its ability to enhance plant growth through mechanisms such as indole-3-acetic acid (IAA) production, which is a natural plant hormone that stimulates root development. This trait not only aids in plant health but also contributes to improved nutrient uptake, making it an important organism in sustainable agriculture. Furthermore, this bacterium is of interest in the field of bioremediation due to its capacity to degrade various environmental pollutants, including certain hydrocarbons. Its metabolic versatility allows it to adapt to diverse ecological niches, which is a key factor in its potential use for cleaning up contaminated environments. Overall, Pseudomonas chlororaphis stands out as a multi-faceted organism with significant implications for agriculture, environmental science, and biotechnology, making it a subject of ongoing research and interest in microbial ecology.

Taxonomy

Superkingdom: Bacteria

Phylum: Pseudomonadota

Class: Gammaproteobacteria

Order: Pseudomonadales

Family: Pseudomonadaceae

Genus: Pseudomonas

Species: Pseudomonas chlororaphis

NCBI ID

587753

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/014/524/625/GCA_014524625.1_ASM1452462v1

File for sequence-based predictions:
GCA_014524625.1_ASM1452462v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The bacterium Pseudomonas chlororaphis is primarily known for its role in agriculture as a biocontrol agent and plant growth promoter. However, its clinical implications are noteworthy, particularly in the context of infections and antimicrobial resistance. While Pseudomonas chlororaphis is not typically associated with human disease, it is closely related to the more pathogenic species Pseudomonas aeruginosa, which is a significant opportunistic pathogen in immunocompromised individuals. This relationship raises concerns about potential pathogenicity and the ability of Pseudomonas chlororaphis to acquire virulence factors under certain conditions. In terms of antimicrobial resistance, there is a growing body of evidence suggesting that environmental bacteria, including Pseudomonas chlororaphis, can harbor resistance genes that may be transferred to more pathogenic species. This poses a risk for the development of multidrug-resistant infections, particularly in hospital settings where antibiotic use is prevalent. Moreover, the organism's ability to produce secondary metabolites, such as antibiotics, has been explored for potential therapeutic applications. These metabolites may have implications in the development of new antimicrobial agents or as part of probiotic formulations aimed at enhancing human health. Overall, while Pseudomonas chlororaphis is not a primary pathogen, its ecological role and genetic capabilities warrant further investigation to fully understand its potential impact on human health and disease.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Pseudomonas chlororaphis has demonstrated significant potential in various industrial applications. One of the most notable areas is in biotechnology, where Pseudomonas chlororaphis is utilized for its ability to produce bioactive compounds such as antibiotics and plant growth-promoting substances. This organism is particularly effective in fermentation processes, where it can be harnessed to synthesize valuable metabolites that enhance agricultural productivity. In the realm of waste management, Pseudomonas chlororaphis plays a crucial role in the biodegradation of environmental pollutants. Its enzymatic activity allows it to break down complex organic compounds, making it a valuable asset in bioremediation efforts aimed at cleaning contaminated soils and water bodies. Furthermore, this microorganism is being explored for its potential in biofuel production. Through fermentation processes, Pseudomonas chlororaphis can convert biomass into biofuels, contributing to sustainable energy solutions. Its metabolic pathways are being studied to optimize the yield of biofuels from various organic substrates. In pharmaceutical development, the antibiotic properties of Pseudomonas chlororaphis are of particular interest. Researchers are investigating its ability to produce novel compounds that could lead to the development of new antimicrobial agents, addressing the growing concern of antibiotic resistance. Overall, Pseudomonas chlororaphis showcases a diverse range of applications across multiple industries, highlighting its importance in advancing both environmental sustainability and health-related innovations.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 8

LLM predicted phenotypes: 5

Phenotype	High-quality annotation	openai/gpt-3.5-turbo-0125	google/gemini-pro-1.5	anthropic/claude-3.5-sonnet	meta-llama/llama-3-8b-instruct:nitro	google/gemini-flash-1.5	meta-llama/llama-3-70b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	google/gemma-7b-it	openchat/openchat-7b	mistralai/mixtral-8x7b-instruct:nitro	openai/gpt-4	openai/gpt-4	anthropic/claude-3-haiku:beta	anthropic/claude-3-haiku:beta	openai/gpt-4o	openai/gpt-4o	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	mistralai/mistral-7b-instruct	mistralai/mistral-7b-instruct	google/gemini-pro	google/gemini-pro
Motility	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Gram staining	gram stain negative	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	N/A	false	false	false	true	false	true	false	true	false	false	false	false	true	true	false	false	false	false	false	false	false	false	true	true	false	false
Biofilm formation	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Animal pathogenicity	TRUE	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	true ✓	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false	true	true	false	false	true	true
Host association	TRUE	false ✗	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	false ✗	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Plant pathogenicity	FALSE	true ✗	true ✗	false ✓	false ✓	false ✓	true ✗	false ✓	true ✗	true ✗	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓
Spore formation	N/A	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false
Hemolysis	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	alpha	alpha	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓

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