Vibrio mimicus

General Information

Vibrio mimicus is a fascinating microorganism that has garnered significant attention in the field of microbiology due to its close resemblance to Vibrio cholerae, the causative agent of cholera. One of the most intriguing aspects of Vibrio mimicus is its ability to produce cholera-like symptoms, including severe diarrhea, which makes it an important subject of study for understanding gastrointestinal diseases. Vibrio mimicus is typically found in aquatic environments, particularly in brackish and marine waters. This environmental preference highlights its role in the ecology of waterborne pathogens and its potential impact on public health, especially in regions where water sanitation is a concern. Genetically, Vibrio mimicus shares many similarities with Vibrio cholerae, including the presence of virulence factors such as the cholera toxin gene (ctx). However, it also possesses unique genetic elements that distinguish it from its more infamous relative. This genetic overlap and divergence make Vibrio mimicus an excellent model for studying the evolution of pathogenicity and the genetic mechanisms underlying virulence. From a research perspective, Vibrio mimicus is valuable for its role in comparative studies with Vibrio cholerae. By examining the differences and similarities between these two species, scientists can gain insights into the molecular basis of virulence, host-pathogen interactions, and the development of potential treatments or preventive measures for cholera and other related diseases. In summary, Vibrio mimicus is a microorganism of significant interest due to its pathogenic potential, environmental niche, and genetic relationship with Vibrio cholerae. Its study not only enhances our understanding of microbial ecology and evolution but also has important implications for public health and disease management.

Vibrio mimicus is a fascinating marine bacterium that is primarily associated with aquatic environments, particularly in tropical and subtropical regions. This organism is notable for its ability to thrive in brackish waters, which makes it an important player in the ecology of coastal ecosystems. One of the most interesting aspects of V. mimicus is its pathogenic potential; it has been implicated in gastrointestinal illnesses in humans, particularly through the consumption of contaminated seafood. This characteristic makes it a subject of interest for researchers studying food safety and public health. The bacterium is closely related to Vibrio cholerae, the causative agent of cholera, and shares some genetic and phenotypic traits with it. However, V. mimicus is distinguished by its unique virulence factors and the specific conditions under which it can cause disease. Research into the genetic makeup of V. mimicus has revealed insights into its adaptability and survival mechanisms in fluctuating environmental conditions, which is crucial for understanding its role in marine ecosystems. Furthermore, V. mimicus has been studied for its potential in biotechnological applications, particularly in the field of aquaculture, where it can influence the health of marine organisms. Its ability to produce certain enzymes and metabolites may also have implications for bioremediation efforts in polluted marine environments. Overall, Vibrio mimicus serves as a valuable model organism for studying the interactions between marine bacteria and their environments, as well as their impacts on human health.

Taxonomy

Superkingdom: Bacteria

Phylum: Pseudomonadota

Class: Gammaproteobacteria

Order: Vibrionales

Family: Vibrionaceae

Genus: Vibrio

Species: Vibrio mimicus

NCBI ID

674

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/019/048/845/GCA_019048845.1_ASM1904884v1

File for sequence-based predictions:
GCA_019048845.1_ASM1904884v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Vibrio mimicus is a gram-negative bacterium that is primarily associated with gastrointestinal infections and is known to cause diarrheal diseases in humans. It is closely related to Vibrio cholerae, the causative agent of cholera, and shares some pathogenic characteristics, including the ability to produce enterotoxins that can lead to severe fluid loss and dehydration. Infections with Vibrio mimicus are often linked to the consumption of contaminated seafood, particularly raw or undercooked shellfish, which poses a significant risk in coastal regions where the organism is endemic. Clinical implications of Vibrio mimicus infections include the potential for acute gastroenteritis, characterized by symptoms such as diarrhea, abdominal cramps, nausea, and vomiting. In some cases, particularly in immunocompromised individuals, the infection can lead to more severe outcomes, including sepsis or wound infections following exposure to contaminated water. The organism exhibits antimicrobial resistance, which complicates treatment options. Resistance to commonly used antibiotics has been documented, making it essential for clinicians to perform susceptibility testing to guide effective therapy. The mechanisms of resistance may involve the acquisition of resistance genes through horizontal gene transfer, which is a common trait among many members of the Vibrio genus. In terms of immune evasion, Vibrio mimicus can modulate its surface structures and produce factors that inhibit the host's immune response, allowing it to persist in the gastrointestinal tract and evade clearance by the immune system. This ability to adapt and survive in hostile environments contributes to its pathogenicity. While Vibrio mimicus is primarily recognized for its role in foodborne illnesses, it has not been extensively studied for potential medical applications such as probiotics or vaccines. However, understanding its pathogenic mechanisms and interactions with the human host can provide insights into developing preventive measures against infections caused by this organism.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Vibrio mimicus is a halophilic bacterium commonly associated with marine environments and brackish waters. This microorganism thrives in areas with elevated salinity, often found in coastal regions, estuaries, and mangrove swamps. Its presence is particularly noted in the tropical and subtropical coastal waters, where it can be isolated from various aquatic organisms, including fish and shellfish. In these marine ecosystems, Vibrio mimicus plays a significant role as a decomposer, breaking down organic matter and contributing to nutrient cycling. It is also known for its potential pathogenicity, particularly in relation to seafood consumption, which highlights its role in the food web and its interactions with marine life. The bacterium exhibits symbiotic relationships with certain marine organisms, where it may provide benefits such as enhanced nutrient availability or protection against pathogens. Additionally, Vibrio mimicus has adapted to varying salinity levels, showcasing its resilience in fluctuating environmental conditions, which is crucial for its survival in dynamic coastal habitats. Overall, the ecological niche of Vibrio mimicus is characterized by its adaptability to saline environments, its role in nutrient cycling, and its interactions with both biotic and abiotic components of the marine biome.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Vibrio mimicus has shown potential in various industrial applications, particularly in the fields of biotechnology and waste management. This organism is known for its ability to thrive in marine environments, which makes it a candidate for processes involving biodegradation of organic pollutants in aquatic systems. Its enzymatic activity can facilitate the breakdown of complex organic compounds, contributing to the detoxification of contaminated water bodies. In the realm of biofuel production, Vibrio mimicus can be utilized in fermentation processes to convert biomass into bioethanol. The organism's metabolic pathways allow it to ferment sugars derived from marine biomass, potentially leading to sustainable energy solutions. Moreover, Vibrio mimicus has been studied for its role in pharmaceutical development. Its unique biochemical properties may lead to the discovery of novel compounds with antimicrobial or antifungal activities, which can be harnessed in drug formulation. Overall, the versatility of Vibrio mimicus in these applications highlights its significance in advancing sustainable practices and innovative solutions across multiple industries.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	google/gemini-pro-1.5	anthropic/claude-3.5-sonnet	google/gemma-7b-it	meta-llama/llama-3-70b-instruct:nitro	google/gemini-flash-1.5	mistralai/mixtral-8x7b-instruct:nitro	openai/gpt-4	openai/gpt-4	openai/gpt-4o	openai/gpt-4o	anthropic/claude-3-haiku:beta	mistralai/mistral-7b-instruct	meta-llama/llama-3-8b-instruct:nitro	google/gemini-pro	google/gemini-pro	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	perplexity/llama-3-sonar-small-32k-chat	perplexity/llama-3-sonar-small-32k-chat	openchat/openchat-7b	openchat/openchat-7b	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct
Motility	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Gram staining	gram stain negative	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓
Aerophilicity	N/A	facultatively anaerobic	facultatively anaerobic	N/A	N/A	N/A	facultatively anaerobic	facultatively anaerobic	facultatively anaerobic	facultatively anaerobic	facultatively anaerobic	N/A	N/A	N/A	N/A	N/A	facultatively anaerobic	facultatively anaerobic	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Biofilm formation	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Animal pathogenicity	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Biosafety level	biosafety level 2	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓
Health association	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Host association	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	N/A	beta	beta	alpha	beta	beta	N/A	beta	beta	beta	beta	beta	N/A	N/A	gamma	gamma	N/A	N/A	beta	beta	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	spirillum ✗	spirillum ✗

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